Detalhe da pesquisa
1.
Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome.
PLoS Genet
; 17(1): e1009224, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33417599
2.
Titration-based normalization of antibody amount improves consistency of ChIP-seq experiments.
BMC Genomics
; 24(1): 171, 2023 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37016279
3.
The landscape of metabolic brain alterations in Alzheimer's disease.
Alzheimers Dement
; 2022 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35829654
4.
Epigenomic features related to microglia are associated with attenuated effect of APOE ε4 on Alzheimer's disease risk in humans.
Alzheimers Dement
; 18(4): 688-699, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34482628
5.
Whole genome sequencing-based copy number variations reveal novel pathways and targets in Alzheimer's disease.
Alzheimers Dement
; 18(10): 1846-1867, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34918867
6.
Latent trait modeling of tau neuropathology in progressive supranuclear palsy.
Acta Neuropathol
; 141(5): 667-680, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33635380
7.
Integrative functional genomic analysis of intron retention in human and mouse brain with Alzheimer's disease.
Alzheimers Dement
; 17(6): 984-1004, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33480174
8.
EPIGENOMIC FEATURES RELATED TO MICROGLIA ARE ASSOCIATED WITH ATTENUATED EFFECT OF APOE ε4 ON ALZHEIMER'S DISEASE RISK IN HUMANS.
Alzheimers Dement
; 16(Suppl 2)2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34393677
9.
MAPT haplotype-stratified GWAS reveals differential association for AD risk variants.
Alzheimers Dement
; 16(7): 983-1002, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32400971
10.
Genome-wide transcriptome analysis identifies novel dysregulated genes implicated in Alzheimer's pathology.
Alzheimers Dement
; 16(9): 1213-1223, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32755048
11.
Tau and apolipoprotein E modulate cerebrovascular tight junction integrity independent of cerebral amyloid angiopathy in Alzheimer's disease.
Alzheimers Dement
; 16(10): 1372-1383, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32827351
12.
Divergent brain gene expression patterns associate with distinct cell-specific tau neuropathology traits in progressive supranuclear palsy.
Acta Neuropathol
; 136(5): 709-727, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30136084
13.
Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases.
Alzheimers Dement
; 14(3): 352-366, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29107053
14.
Systems biology approach to late-onset Alzheimer's disease genome-wide association study identifies novel candidate genes validated using brain expression data and Caenorhabditis elegans experiments.
Alzheimers Dement
; 13(10): 1133-1142, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28242297
15.
A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression.
Alzheimers Dement
; 13(6): 663-673, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-27939925
16.
Gene expression, methylation and neuropathology correlations at progressive supranuclear palsy risk loci.
Acta Neuropathol
; 132(2): 197-211, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27115769
17.
MAPT haplotype H1G is associated with increased risk of dementia with Lewy bodies.
Alzheimers Dement
; 12(12): 1297-1304, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27287057
18.
Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants.
PLoS Genet
; 8(6): e1002707, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22685416
19.
Evaluation of memory endophenotypes for association with CLU, CR1, and PICALM variants in black and white subjects.
Alzheimers Dement
; 10(2): 205-13, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23643458
20.
Bridging the Gap: Multi-Omics Profiling of Brain Tissue in Alzheimer's Disease and Older Controls in Multi-Ethnic Populations.
bioRxiv
; 2024 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38659743