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1.
J Biomech ; 40(12): 2758-66, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17399721

RESUMO

Automotive side impacts are a leading cause of injuries to the pubic symphysis, yet the mechanisms of those injuries have not been clearly established. Previous mechanical testing of isolated symphyses revealed increased joint laxity following drop tower lateral impacts to isolated pelvic bone structures, which suggested that the joints were damaged by excessive stresses and/or deformations during the impact tests. In the present study, a finite element (FE) model of a female pelvis including a previously validated symphysis sub-model was developed from computed tomography data. The full pelvis model was validated against measured force-time impact responses from drop tower experiments and then used to study the biomechanical response of the symphysis during the experimental impacts. The FE models predicted that the joint underwent a combination of lateral compression, posterior bending, anterior/posterior and superior/inferior shear that exceeded normal physiological levels prior to the onset of bony fractures. Large strains occurred concurrently within the pubic ligaments. Removal of the contralateral constraints to better approximate the boundary conditions of a seated motor vehicle occupant reduced cortical stresses and deformations of the pubic symphysis; however, ligament strains, compressive and shear stresses in the interpubic disc, as well as posterior bending of the joint structure remained as potential sources of joint damage during automotive side impacts.


Assuntos
Acidentes de Trânsito , Simulação por Computador , Fraturas Ósseas/fisiopatologia , Modelos Biológicos , Pelve/fisiopatologia , Sínfise Pubiana/fisiopatologia , Força Compressiva , Feminino , Análise de Elementos Finitos , Fraturas Ósseas/patologia , Humanos , Pessoa de Meia-Idade , Pelve/patologia , Sínfise Pubiana/patologia
2.
J Bone Joint Surg Am ; 88(2): 261-6, 2006 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-16452735

RESUMO

BACKGROUND: Deep-vein thrombosis following skeletal trauma is an important yet poorly studied issue. The purpose of the present study was to evaluate the efficacy of two different strategies for prophylaxis against deep-vein thrombosis and pulmonary embolus following blunt skeletal trauma. METHODS: Two hundred and twenty-four inpatients were enrolled in a prospective, randomized study investigating venous thromboembolic disease following trauma. Two hundred patients completed the study, which compared two different regimens of prophylaxis. The patients in Group A received enoxaparin (30 mg, administered subcutaneously twice a day) starting twenty-four to forty-eight hours after blunt trauma. The patients in Group B were managed with pulsatile foot pumps at the time of admission combined with enoxaparin on a delayed basis. All patients were screened with magnetic resonance venography and ultrasonography before discharge. RESULTS: There were ninety-seven patients in Group A and 103 patients in Group B. Twenty-two patients (including thirteen in Group A and nine in Group B) had development of deep-vein thrombosis, with two (both in Group A) also having development of pulmonary embolism. The prevalence of deep-vein thrombosis was 11% for the whole series, 13.4% for Group A, and 8.7% for Group B; the difference between Groups A and B was not significant. There were eleven large or occlusive clots (prevalence, 11.3%) in Group A, compared with only three (prevalence, 2.9%) in Group B (p = 0.025). The prevalence of pulmonary embolism was 2.1% in Group A and 0% in Group B. Wound complications occurred in twenty-one patients in Group A, compared with twenty patients in Group B. Patients who had development of deep-vein thrombosis during the inpatient portion of the study required a mean of 7.4 units of blood during hospitalization, compared with 3.9 units of blood for those who did not (p < 0.05). CONCLUSIONS: Our results indicate that early mechanical prophylaxis with foot pumps and the addition of enoxaparin on a delayed basis is a very successful strategy for prophylaxis against venous thromboembolic disease following serious musculoskeletal injury. The prevalence of large or occlusive deep-vein thromboses among patients who had been managed with this protocol was significantly less than that among patients who had been managed with enoxaparin alone.


Assuntos
Anticoagulantes/uso terapêutico , Enoxaparina/uso terapêutico , Trombose Venosa/prevenção & controle , Adulto , Idoso , Idoso de 80 Anos ou mais , Método Duplo-Cego , Humanos , Pessoa de Meia-Idade , Procedimentos Ortopédicos , Estudos Prospectivos , Trombose Venosa/etiologia , Ferimentos não Penetrantes/complicações
3.
J Orthop Res ; 23(2): 359-66, 2005 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-15734249

RESUMO

Acetabular fractures are an especially problematic outcome of motor vehicle side impacts. While fracture type has been correlated with impact direction and femoral orientation, actual contact pressures in the hip joint have not been quantified for lateral loading conditions. In the present study, we used pressure sensitive film to measure contact areas and pressures in seven hip joints from four cadavers under quasi-static lateral loading through the greater trochanter. The aim was to quantify the interactions of the femoral head with the acetabulum associated with variations in femoral orientation. Three angles of hip flexion (80 degrees , 90 degrees , 100 degrees ) and hip abduction (-10 degrees , 0 degrees , 10 degrees ) were tested, producing nine test orientations for each joint. We observed that contact areas, pressures, and forces varied significantly with femoral orientation for the adducted hip. The principal locations of load transmission were in the anterior and posterior regions of the acetabulum. For the abducted femur, contact pressures were concentrated anteriorly, and with increased adduction, anterior contact pressures diminished while posterior and superior pressures increased. The movement of pressure sites was consistent with mechanisms of acetabular fractures described by Letournel and Judet and provides new data for validation of finite element models of the pelvis in side impact.


Assuntos
Acetábulo/fisiologia , Cabeça do Fêmur/fisiologia , Articulação do Quadril/fisiologia , Acetábulo/lesões , Idoso , Fenômenos Biomecânicos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Pressão
4.
J Bone Joint Surg Am ; 85(11): 2103-10, 2003 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-14630838

RESUMO

BACKGROUND: Studies on intramedullary nailing of humeral shaft fractures in the orthopaedic literature have shown mixed results. The purpose of this investigation was to document the clinical outcome and complications associated with the use of a new flexible, locking intramedullary nail that can be implanted in the humerus in either a retrograde or an antegrade manner without violating the rotator cuff mechanism or damaging the articular surface of the humeral head. METHODS: Fifty consecutive patients with fifty-one humeral shaft fractures were entered into our prospective clinical outcome study. The fracture was classified on the basis of the anatomic location and pattern. Implant positioning and fracture alignment were assessed postoperatively. Complications were recorded, and the time to union was measured. Shoulder function was evaluated with use of a combination of the Constant shoulder score, Short Form-36 (SF-36) clinical outcome data, range-of-motion measurements, and a subjective pain-rating scale. RESULTS: Forty-one patients with forty-two fractures had an adequate duration of clinical follow-up (a mean of twenty-two months) for analysis. Thirty-nine fractures healed, with a mean time to clinical union of twelve weeks (range, four to fifty weeks). Thirty-eight of the forty-two shoulders had minimal or no pain. Thirty-six shoulders had a full range of motion. The mean Constant shoulder score was 90 points. Four patients had five complications, which included two nonunions, two hardware failures, and one wound infection. All four patients had been managed with a 7.5-mm nail. A multivariate analysis demonstrated that an age of more than fifty years was associated with a lower Constant score and that the occurrence of a complication was associated with a lower physical component score on the SF-36. CONCLUSIONS: The flexible humeral nail allows both retrograde and antegrade implantation and static locking. Nail insertion can be accomplished without violating the rotator cuff or damaging the articular surface of the humeral head. Although the nail functioned well in most of our patients, the use of a small-diameter (7.5-mm) nail was associated with a higher complication rate. This implant should be used with caution in any patient with a medullary canal diameter of

Assuntos
Pinos Ortopédicos/efeitos adversos , Fixação Intramedular de Fraturas/instrumentação , Fraturas não Consolidadas/etiologia , Fraturas do Úmero/cirurgia , Falha de Prótese , Infecção da Ferida Cirúrgica/etiologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Resultado do Tratamento
5.
J Biomech ; 36(2): 219-27, 2003 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-12547359

RESUMO

Pelvic fractures resulting from automotive side impacts are associated with high mortality and morbidity, as well as substantial economic costs. Previous experimental studies have produced varying results regarding the tolerance of the pelvis to lateral force and compression. While bone mineral density (BMD) has been shown to correlate with fracture loads in the proximal femur, no such correlation has been established for the pelvis. Presently, we studied the relationships between total hip BMD and impact response parameters in lateral impacts of twelve isolated human pelves. The results indicated that total hip BMD significantly correlated with fracture force, Fmax, and maximum ring compression, Cmax, of the fractured pelves. These findings are evidence that BMD may be useful in assessing the risk of pelvic fracture in automotive side impacts. Poor correlation was observed between total hip BMD and maximum viscous response, (VC)max, energy at fracture, Epeak, and time to fracture, tpeak. Mean Fmax and calculated tolerances for Cmax and (VC)max were lower than those established in previous studies using full cadavers, likely a result of our removal of soft tissues from the pelves prior to impact.


Assuntos
Densidade Óssea/fisiologia , Fraturas Ósseas/fisiopatologia , Ossos Pélvicos/fisiopatologia , Suporte de Carga , Adulto , Idoso , Idoso de 80 Anos ou mais , Cadáver , Força Compressiva , Feminino , Fraturas Ósseas/etiologia , Fraturas Ósseas/prevenção & controle , Humanos , Técnicas In Vitro , Masculino , Pessoa de Meia-Idade , Ossos Pélvicos/lesões , Estatística como Assunto , Estresse Mecânico , Ferimentos não Penetrantes/complicações , Ferimentos não Penetrantes/prevenção & controle
6.
Am Surg ; 69(12): 1019-23; discussion 1023-4, 2003 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-14700284

RESUMO

This retrospective study reports outcomes, after early and delayed surgical stabilization of fractures of the pelvic ring, in terms of pulmonary complications, length of hospital stay, and cost of hospitalization. The hospital course of 151 patients admitted to an academic teaching hospital who sustained acute fractures of the pelvic ring between June 1996 and December 2000 was reviewed. Patient demographics, Injury Severity Score (ISS), timing of operative fixation, and the incidence of pulmonary complications were analyzed. Radiographs were reviewed and fractures classified according to the modified Tile system. Tile fracture types B and C patients who underwent fixation within 1 week of injury (n = 71) were compared to those in whom surgery was delayed (n = 28). Adjusting for the ISS, early-repair patients had a lower risk of pulmonary complications (RR = 0.49, 95% CI = 0.25-0.96), a reduced length of hospital stay (12.2 vs. 20.5 days; P = 0.0005), and overall reduced cost of care (57,084 dollars vs. 158,625 dollars; P = 0.0317). Pelvic ring fixation within the first week of injury results in significantly reduced incidence of pulmonary complication, hospital stay, and cost of care regardless of injury severity. The coordinated team approach to insure prompt resuscitation, stabilization, and operative fixation results in more optimal patient outcomes.


Assuntos
Fixação Interna de Fraturas/métodos , Fraturas Fechadas/cirurgia , Ossos Pélvicos/lesões , Adulto , Feminino , Fixação Interna de Fraturas/economia , Humanos , Escala de Gravidade do Ferimento , Tempo de Internação , Pneumopatias/prevenção & controle , Masculino , Complicações Pós-Operatórias/prevenção & controle , Estudos Retrospectivos , Fatores de Tempo , Resultado do Tratamento
7.
J Orthop Trauma ; 18(8): 552-8, 2004 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-15475852

RESUMO

OBJECTIVES: To report on the use of a new plating system in the treatment of high-energy tibial plateau fractures using minimally invasive stabilization techniques. DESIGN: Prospective, consecutive patient series. SETTING: University Level I trauma center. PATIENTS: Thirty-seven patients with 39 fractures of the tibial plateau were treated using specialty plates. All fractures were OTA class 41C. Ten of the fractures were open, including eight Gustilo and Anderson Type IIIA and two Type IIIB. Thirty-three patients with 34 fractures had follow-up of at least 12 months. INTERVENTION: Internal fixation with the Less Invasive Stabilization System (LISS, Synthes USA, Paoli, PA) using minimally invasive techniques. MAIN OUTCOME MANAGEMENT: To determine clinical outcome, time to union, fracture alignment, articular step-off, incidence of complications, Short Form-36 outcome scores, and Lysholm knee scores in patients with associated ligament injuries. RESULTS: All 34 of the fractures healed without additional surgical intervention or bone grafting. The mean follow-up in our series was 21 months, with a range of 12 to 38 months. Twenty-nine patients with 30 fractures had follow-up of greater than 1 year. The average time to radiographic callus was 6.1 weeks, and the average time to complete union was 15.6 weeks. The articular step-off average was 0.8 mm, with a range of 0 to 5 mm. The postoperative alignment demonstrated 1 patient with a malalignment of 5 degrees procurvatum and 1 patient with 4 degrees of valgus. There were two superficial wound infections and no cases of deep infection or osteomyelitis. CONCLUSIONS: The use of LISS plates appears to stabilize complex fractures of the tibial plateau with a low incidence of complications. The LISS system functioned well in maintaining alignment and obtaining union in these high-energy fractures.


Assuntos
Fixação de Fratura/métodos , Fraturas da Tíbia/cirurgia , Adulto , Idoso , Idoso de 80 Anos ou mais , Parafusos Ósseos , Desenho de Equipamento , Feminino , Fixação de Fratura/instrumentação , Humanos , Masculino , Pessoa de Meia-Idade , Procedimentos Cirúrgicos Minimamente Invasivos/instrumentação , Procedimentos Cirúrgicos Minimamente Invasivos/métodos , Estudos Prospectivos , Fraturas da Tíbia/classificação , Centros de Traumatologia , Resultado do Tratamento
8.
J Orthop Trauma ; 17(6): 406-10, 2003 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-12843724

RESUMO

OBJECTIVE: To study the incidence and nature of pelvic fractures in rapidly fatal automobile accidents. DESIGN: Retrospective. SETTING: County Medical Examiner's Office. PATIENTS: The files of 255 consecutive motor vehicle accident fatalities examined at the Jefferson County Coroner/Medical Examiner's office (study period 1996-1998) were reviewed. We correlated this information with our previous findings, derived from a review of 392 such cases (study period 1994-1996). RESULTS: Approximately 25% of decedents involved in rapidly fatal automobile accidents sustained pelvic fractures. In 93% of the cases, postmortem radiographs were available and suitable for scoring according to the Orthopaedic Trauma Association nomenclature. The distribution of pelvic fractures by type was type A, 16%; type B, 32%; and type C, 52%, with the most common pelvic fracture being type C1 (26%). Additionally, pedestrians and motorcyclists were twice as likely to sustain a pelvic fracture, and the severity of pelvic fracture type seemed to correlate with increasing speed of the automobile. No correlation between drug use or direction of impact and incidence or type of pelvic fracture was observed. Compared with published studies on survivors of automobile accidents, our data suggest that pelvic injuries may tend to be more severe in victims who do not survive to hospitalization. CONCLUSIONS: Our data indicate that current estimates about the mortality of pelvic fractures may be faulty due to exclusion of victims who fail to survive to hospitalization. This series suggests that an appreciation of the full spectrum of pelvic ring disruptions requires collaboration between orthopaedic surgeons and forensic pathologists.


Assuntos
Acidentes de Trânsito , Fraturas Ósseas/classificação , Ossos Pélvicos/lesões , Acidentes de Trânsito/mortalidade , Acidentes de Trânsito/estatística & dados numéricos , Adulto , Alabama/epidemiologia , Fraturas Ósseas/diagnóstico por imagem , Humanos , Incidência , Pessoa de Meia-Idade , Radiografia , Estudos Retrospectivos
9.
Arthroscopy ; 19(6): 626-31, 2003.
Artigo em Inglês | MEDLINE | ID: mdl-12861201

RESUMO

PURPOSE: This study documents short-term clinical outcomes in patients with knee dislocations after blunt trauma and evaluates the compass knee hinge (CKH) external fixator for their treatment. TYPE OF STUDY: Nonrandomized prospective functional outcome study. METHODS: Forty patients with 43 knee dislocations were evaluated. Twelve knees underwent ligament reconstruction followed by placement of a CKH; this was group A. Group B included 27 knees that underwent the same treatment and rehabilitation protocol except that an external brace was used rather than a CKH. RESULTS: Thirty-six patients with 39 knee dislocations underwent follow-up ranging from 14 to 41 months (mean, 24). Four patients with 4 knee dislocations were lost to follow-up (1 group A, 3 group B). Group A underwent 27 knee ligament procedures with 2 (7%) failures based on clinical examination. Group B underwent 102 ligament procedures with 30 (29%) failures (P <.05). Anterior cruciate ligament (ACL) reconstruction revealed that 7 group A patients experienced 1 (14%) failure and 25 Group B patients experienced 7 (28%) failures. Posterior cruciate ligament (PCL) reconstruction in 7 group A patients included no failures, and 20 PCL reconstructions in group B included 1 failure. Reconstruction of the posterolateral corner (PLC) yielded no failures in 2 group A patients and 5 (25%) of 20 in group B. Repair of 8 PLCs in group A yielded 1 (12.5%) failure and 26 PLC repairs in group B had 14 (54%; P =.05). SF-36 data revealed low mean values with no significant differences between groups with current enrollment. CONCLUSIONS: Knee dislocation after blunt trauma requires aggressive surgical treatment and physical therapy. In the short-term evaluation, the CKH allows aggressive physical therapy without placing repaired or reconstructed ligaments under high stresses that can result in failure.


Assuntos
Ligamento Cruzado Anterior/cirurgia , Artroplastia , Fixadores Externos , Luxação do Joelho/cirurgia , Ligamento Cruzado Posterior/cirurgia , Acidentes de Trânsito , Adolescente , Adulto , Idoso , Lesões do Ligamento Cruzado Anterior , Feminino , Seguimentos , Humanos , Luxação do Joelho/reabilitação , Masculino , Pessoa de Meia-Idade , Traumatismo Múltiplo/reabilitação , Traumatismo Múltiplo/cirurgia , Ligamento Cruzado Posterior/lesões , Estudos Prospectivos , Estudos Retrospectivos , Resultado do Tratamento , Ferimentos não Penetrantes/cirurgia
10.
Arthroscopy ; 18(8): 835-9, 2002 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-12368779

RESUMO

PURPOSE: The purpose of this study was to determine the prevalence of heterotopic ossification following knee dislocation. TYPE OF STUDY: Prospective clinical evaluation and a retrospective chart review. METHODS: This study evaluated 57 knees in 55 patients who sustained high-energy blunt trauma with resultant knee dislocations. Radiographs were reviewed by 2 of the authors (J.P.S., T.C.W.), and the incidence of heterotopic ossification (HO) was documented. Additionally, patients were classified regarding the degree of HO on a scale from 0 to 4. One is punctate calcification, 2 is HO involving less than 50% of the joint space; 3 is HO involving more than 50%; and 4 is ankylosis of the joint. RESULTS: Thirteen patients with 15 knee dislocations developed HO. The incidence of HO was 26%. Seven knees demonstrated severe HO (grade 3 or 4) which represented an incidence of 12% of all knee dislocations. Injury severity score for both groups was 18, documenting that the patients in this study represent multiple trauma patients. There was no significant difference in the incidence of HO based on mechanism of injury with the current number enrolled in the study. However, 60% (3 of 5) of patients involved in a motor vehicle versus pedestrian accident developed HO. There was a significant increase in the incidence of arthrofibrosis in patients with severe HO (P <.05). Patients with significant HO had a mean flexion of 97 degrees, compared with flexion of 117 degrees in patients with no or mild HO. This difference was borderline significant (P =.058). There was no difference between the groups in mean extension. There was a significant increase in knee HO in patients with HO at another anatomic site (P =.01). CONCLUSIONS: HO is a common problem following knee dislocation. Of the 7 knees with severe HO, 5 developed HO medially, 4 developed HO posteriorly, 3 developed HO laterally, and only 1 had involvement anteriorly. A similar distribution was present in the patients with mild HO, with posterior and medial ossification being the most common. Five of the 7 severe HO cases involved at least 3 of the 4 sides (anterior, posterior, medial, or lateral) of the knee. Patients were evaluated for the presence of head injury and any relationship to the development of HO around the knee. There was no increased incidence of HO around the knee in our 10 patients with severe head injuries when compared with those with no head injury. There was also no increased incidence of HO in knee dislocations associated with periarticular fractures.


Assuntos
Luxações Articulares/epidemiologia , Traumatismos do Joelho/epidemiologia , Ossificação Heterotópica/epidemiologia , Ferimentos não Penetrantes/epidemiologia , Adolescente , Adulto , Comorbidade , Feminino , Humanos , Escala de Gravidade do Ferimento , Masculino , Pessoa de Meia-Idade , Ossificação Heterotópica/classificação , Prevalência , Estudos Prospectivos , Fatores de Risco
11.
Injury ; 41 Suppl 2: S90-3, 2010 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-21144937

RESUMO

OBJECTIVE: To measure the amount of fat presented to the right heart during reaming and nail placement using two different reamer systems. DESIGN: Prospective, randomized clinical trial. SETTING: University-based Level I Trauma Center. PATIENTS: 20 patients with femur fractures. INTERVENTION: Patients with femur fractures were treated with intramedullary nailing using either reamer-irrigator-aspirator or a conventional reamer. MAIN OUTCOME MEASURE: four-chamber trans-esophageal echocardiogram was used to quantify the amount of fat presented to the right atrium. RESULTS: There were 2 female and 18 male patients enrolled, 10 in each group. There was no significant difference (p = 0.10) between reaming systems on the opening reamer, which was expected since both trial limbs used the same opening reamer. However, during the first pass of the reamer, the RIA showed a nearly-significant decrease in the volume of fat in the right atrium (p = 0.06). During passage of the nail, there was a significant difference with Group B having less fat embolus than Group A (p = 0.01). The power of this study is 0.81. The mean ISS was not significantly different between the two groups, nor was the sex, age or race. There was one death from cardiac complications in a patient who showed no fat during any phase of the procedure. This patient had significant mitral and aortic regurgitation pre-operatively. There was one patient with clinical fat embolism syndrome and one patient with a nonunion. CONCLUSIONS: There is a statistically significant difference in the amount of fat presented to the lungs using a RIA versus conventional reamer.


Assuntos
Embolia Gordurosa/diagnóstico , Fraturas do Fêmur/cirurgia , Fixação Intramedular de Fraturas/métodos , Cardiopatias/etiologia , Coleta de Tecidos e Órgãos/efeitos adversos , Adulto , Idoso , Medula Óssea , Eletrocardiografia , Embolia Gordurosa/etiologia , Feminino , Fixação Intramedular de Fraturas/instrumentação , Cardiopatias/diagnóstico , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Irrigação Terapêutica/instrumentação , Irrigação Terapêutica/métodos , Coleta de Tecidos e Órgãos/instrumentação , Centros de Traumatologia , Adulto Jovem
12.
J Orthop Trauma ; 23(8): 552-7, 2009 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-19704269

RESUMO

OBJECTIVES: To evaluate the impact of negative pressure wound therapy (NPWT) after severe open fractures on deep infection. DESIGN: Prospective randomized study. SETTING: Academic level I trauma center. PATIENTS/PARTICIPANTS: Fifty-nine patients with 63 severe high-energy open fractures were enrolled in this study, with data available on 58 patients with 62 open fractures. INTERVENTION: Twenty-three patients with 25 fractures randomized to the control group and underwent initial irrigation and debridement followed by standard fine mesh gauze dressing, with repeat irrigation and debridement every 48-72 hours until wound closure. Thirty-five patients randomized to the NPWT group and had identical treatment except that NPWT was applied to the wounds between irrigation and debridement procedures until closure. MAIN OUTCOME MEASUREMENTS: The presence or absence of deep wound infection or osteomyelitis, wound dehiscence, and fracture union were primary outcome measures. RESULTS AND CONCLUSIONS: Control patients developed 2 acute infections (8%) and 5 delayed infections (20%), for a total of 7 deep infections (28%), whereas NPWT patients developed 0 acute infections, 2 delayed infections (5.4%), for a total of 2 deep infections (5.4%). There is a significant difference between the groups for total infections (P = 0.024). The relative risk ratio is 0.199 (95% confidence interval: 0.045-0.874), suggesting that patients treated with NPWT were only one-fifth as likely to have an infection compared with patients randomized to the control group. NPWT represents a promising new therapy for severe open fractures after high-energy trauma.


Assuntos
Antibacterianos/administração & dosagem , Desbridamento/efeitos adversos , Fraturas Expostas/complicações , Fraturas Expostas/cirurgia , Tratamento de Ferimentos com Pressão Negativa/instrumentação , Tratamento de Ferimentos com Pressão Negativa/métodos , Infecção dos Ferimentos/etiologia , Infecção dos Ferimentos/prevenção & controle , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Terapia Combinada , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Resultado do Tratamento , Adulto Jovem
13.
Ann Biomed Eng ; 34(9): 1452-62, 2006 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-16897423

RESUMO

Three-dimensional finite element (FE) models of human pubic symphyses were constructed from computed tomography image data of one male and one female cadaver pelvis. The pubic bones, interpubic fibrocartilaginous disc and four pubic ligaments were segmented semi-automatically and meshed with hexahedral elements using automatic mesh generation schemes. A two-term viscoelastic Prony series, determined by curve fitting results of compressive creep experiments, was used to model the rate-dependent effects of the interpubic disc and the pubic ligaments. Three-parameter Mooney-Rivlin material coefficients were calculated for the discs using a heuristic FE approach based on average experimental joint compression data. Similarly, a transversely isotropic hyperelastic material model was applied to the ligaments to capture average tensile responses. Linear elastic isotropic properties were assigned to bone. The applicability of the resulting models was tested in bending simulations in four directions and in tensile tests of varying load rates. The model-predicted results correlated reasonably with the joint bending stiffnesses and rate-dependent tensile responses measured in experiments, supporting the validity of the estimated material coefficients and overall modeling approach. This study represents an important and necessary step in the eventual development of biofidelic pelvis models to investigate symphysis response under high-energy impact conditions, such as motor vehicle collisions.


Assuntos
Análise de Elementos Finitos , Modelos Biológicos , Sínfise Pubiana , Suporte de Carga , Acidentes de Trânsito , Força Compressiva , Elasticidade , Humanos , Imageamento Tridimensional/métodos , Vértebras Lombares/lesões , Sínfise Pubiana/lesões , Fraturas da Coluna Vertebral , Estresse Mecânico , Resistência à Tração
14.
J Trauma ; 60(6): 1301-6, 2006 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-16766975

RESUMO

PURPOSE: To evaluate the use of negative pressure wound therapy (NPWT) to augment healing of surgical incisions and hematomas after high-energy trauma. MATERIALS: This study is a prospective randomized evaluation of NPWT in trauma patients, randomizing patients with draining hematomas to either a pressure dressing (group A) or a VAC (group B). Additionally, patients with calcaneus, pilon, and high-energy tibial plateau fractures were randomized to either a standard postoperative dressing or a VAC over the sutures. RESULTS: There were 44 patients randomized into the hematoma study. Group A drained a mean of 3.1 days, compared with only 1.6 days for group B. This difference was significant (p=0.03). The infection rate for group A was 16%, compared with 8% in group B. An additional 44 patients have been randomized into the fracture study. Again, a significant difference (p=0.02) was present when comparing drainage in group A (4.8 days) and group B (1.8 days). No significant difference was present at current enrollment for infection or wound breakdown. DISCUSSION: NPWT has been used on many complex traumatic wounds. Potential mechanisms of action include angiogenesis, increased blood flow, and decreased interstitial fluid. This ongoing randomized study has demonstrated decreased drainage and improved wound healing following both hematomas and severe fractures.


Assuntos
Bandagens , Fraturas Ósseas/cirurgia , Hematoma/terapia , Deiscência da Ferida Operatória/prevenção & controle , Infecção da Ferida Cirúrgica/prevenção & controle , Adulto , Idoso , Idoso de 80 Anos ou mais , Drenagem , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Cuidados Pós-Operatórios , Estudos Prospectivos , Vácuo , Cicatrização
15.
Injury ; 36(3): 380-6, 2005 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-15710154

RESUMO

The purpose of this review is to examine current orthopaedic treatment of gunshot wounds. Surgeons are increasingly confronted by gunshot wounds that occur in both military and civilian settings. Much of the published work has been from military settings. In the United States, low-energy gunshot wounds are very common, and their incidence is increasing elsewhere in the world. Current treatment and its rationale is reviewed and a systematic approach to the assessment and treatment of these injuries is offered, taking into account the entirety of the injury, rather than simply the velocity of the missile.


Assuntos
Procedimentos Ortopédicos/métodos , Ferimentos por Arma de Fogo/cirurgia , Vasos Sanguíneos/lesões , Desbridamento/métodos , Corpos Estranhos/cirurgia , Fraturas Ósseas/etiologia , Fraturas Ósseas/cirurgia , Humanos , Articulações/lesões , Articulações/cirurgia , Traumatismos dos Nervos Periféricos , Fatores de Risco , Infecção dos Ferimentos/terapia
16.
Injury ; 36(3): 373-9, 2005 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-15710153

RESUMO

The purpose of this paper is to review the literature on ballistics and to sort through the plethora of myth and popular opinion. The trauma surgeon is increasingly faced with gunshot wounds. Knowledge of ballistics is important to help in assessing the patterns of wounds that are seen. There are many factors that affect the flight of a bullet to its target. Many of these factors also affect the behaviour of the bullet after it strikes the target. It is primarily these factors that interest the surgeon.


Assuntos
Balística Forense , Ferimentos por Arma de Fogo/cirurgia , Armas de Fogo , Humanos , Escala de Gravidade do Ferimento , Cinética
17.
Ann Biomed Eng ; 33(2): 248-54, 2005 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-15771279

RESUMO

Pelvic fractures continue to be a source of morbidity and mortality for occupants in motor vehicle side impacts, especially among women. Previous studies have produced fracture tolerances for the female pelvis, yet the roles of soft tissues and bone quality remain unclear. Presently, we studied the influence of trochanteric soft tissue thickness (T) and total hip bone mineral density (BMD) on pelvic fracture of 10 female human pelves subject to lateral impact centered over the greater trochanter. Multiple impacts of increasing severity were performed and impact force, energy, impulse, compression, and viscous criteria were quantified. BMD and T were found to be additive predictors of the fracture force. For a given BMD, the force to fracture was significantly higher than that found previously using isolated pelvic bones. Impulse was found to positively correlate with T; however, maximum compression, viscous criterion, and energy to fracture were independent of BMD and T. The force tolerance at 25% probability of fracture found presently (3.16 kN) is substantially below previously reported values. The results suggest that the trochanteric soft tissue thickness and total hip BMD have a significant bearing on fracture outcome for the female pelvis in automotive side impact.


Assuntos
Acidentes de Trânsito , Densidade Óssea , Tecido Conjuntivo/fisiologia , Fraturas Ósseas/fisiopatologia , Ossos Pélvicos/lesões , Ossos Pélvicos/fisiopatologia , Ferimentos não Penetrantes/fisiopatologia , Idoso , Idoso de 80 Anos ou mais , Cadáver , Força Compressiva , Feminino , Fêmur/lesões , Fêmur/fisiopatologia , Fraturas Ósseas/etiologia , Humanos , Técnicas In Vitro , Pessoa de Meia-Idade , Estimulação Física/métodos , Estresse Mecânico , Ferimentos não Penetrantes/complicações
18.
Ann Thorac Surg ; 79(2): e19-20, 2005 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-15680800

RESUMO

The traditional incision for bilateral sequential lung transplantation is the bilateral anterolateral transsternal thoracotomy with approximation of the sternal fragments with interrupted stainless steel wire loops; this technique may be associated with an unacceptable incidence of postoperative sternal disruption causing chronic pain and deformity. Approximation of the sternal ends was achieved with peristernal cables that passed behind the sternum two intercostal spaces above and below the sternal division, which were then passed through metal sleeves in front of the sternum, the cables tensioned, and the sleeves then crimped. Forty-seven patients underwent sternal closure with this method, and satisfactory bone union occurred in all patients. Six patients underwent removal of the peristernal cables: 1 for infection (with satisfactory bone union after the removal of the cables), 3 for cosmetic reasons, 1 during the performance of a median sternotomy for an aortic valve replacement, and 1 in a patient who requested removal before commencing participation in football. This technique of peristernal cable approximation of sternal ends has successfully eliminated the problem of sternal disruption associated with this incision and is a useful alternative for preventing this complication after bilateral lung transplantation.


Assuntos
Transplante de Pulmão/métodos , Esterno/cirurgia , Toracotomia/instrumentação , Toracotomia/métodos , Corpos Estranhos/etiologia , Corpos Estranhos/cirurgia , Humanos , Próteses e Implantes/efeitos adversos , Infecção da Ferida Cirúrgica/etiologia , Infecção da Ferida Cirúrgica/prevenção & controle
19.
Clin Orthop Relat Res ; (419): 46-50, 2004 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-15021130

RESUMO

Humerus fractures comprise 5% to 8% of all fractures. Nonunions are uncommon, but when they occur, they present a challenge to the orthopaedic surgeon and often are debilitating to patients. There are risk factors that may predispose patients to nonunion. Many methods of treating these nonunions have been described with varying degrees of success. We review the literature concerning the treatment of proximal, midshaft, and distal humeral nonunions and describe our treatment protocol based on the literature.


Assuntos
Transplante Ósseo/métodos , Fixação Interna de Fraturas/métodos , Fraturas não Consolidadas/cirurgia , Fraturas do Úmero/cirurgia , Transplante Ósseo/efeitos adversos , Feminino , Fixação Interna de Fraturas/efeitos adversos , Fixação Intramedular de Fraturas/efeitos adversos , Fixação Intramedular de Fraturas/métodos , Consolidação da Fratura/fisiologia , Fraturas não Consolidadas/diagnóstico por imagem , Fraturas não Consolidadas/epidemiologia , Humanos , Fraturas do Úmero/complicações , Fraturas do Úmero/diagnóstico por imagem , Incidência , Escala de Gravidade do Ferimento , Masculino , Complicações Pós-Operatórias , Prognóstico , Radiografia , Recuperação de Função Fisiológica , Medição de Risco , Resultado do Tratamento , Lesões no Cotovelo
20.
Clin Orthop Relat Res ; (399): 110-8, 2002 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-12011699

RESUMO

Fixation of femoral neck fractures is associated with a higher incidence of complications than any other fracture. The rates of nonunion and avascular necrosis with open reduction and internal fixation continue to be unacceptably high. These complications are the main reason for resorting to primary endoprosthetic replacement of the femoral head in the presence of displaced fractures in elderly patients. However, with the increasing life span of the patients with these prostheses, late complications of endoprosthetic replacement of the femoral head are becoming significant. With these complications, it may be argued that the most cost-effective solution to the femoral neck fracture in the majority of patients is open reduction and internal fixation, with elective conversion, when necessary, to total hip arthroplasty in patients who have a complication. Because the literature does not contain a systematic review of reasons for failure of internal fixation, the authors will attempt to review the common means of failure of internal fixation in young and older patients in an attempt to better understand and prevent these complications.


Assuntos
Fraturas do Colo Femoral/cirurgia , Fixação Interna de Fraturas/efeitos adversos , Adulto , Distribuição por Idade , Idoso , Parafusos Ósseos , Feminino , Fraturas do Colo Femoral/diagnóstico por imagem , Seguimentos , Fixação Interna de Fraturas/métodos , Consolidação da Fratura/fisiologia , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Radiografia , Reoperação , Fatores de Risco , Falha de Tratamento
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