Crown heights in the permanent teeth of 45,X and 45,X/46,XX females.

OBJECTIVE: Previous results regarding human sex chromosome aneuploidies have shown that the X and Y chromosomes affect tooth size and morphology. This study looked for the effect of sex chromosome deficiency on permanent tooth crown heights. MATERIALS AND METHODS: The material, from the Finnish KVANTTI Research Project, consisted of 97 45,X females and 15 45,X/46,XX females. The controls were 32 sisters and 28 mothers of the 45,X females, eight sisters and two mothers of the 45,X/46,XX females and 35 female population controls. Crown heights of all the available teeth except third molars on both sides of the jaws were measured from panoramic radiographs with a digital calliper according to the defined procedure. RESULTS: The tooth crown heights were significantly smaller in the 45,X females than in the female population controls, except for the incisors and one canine in the maxilla, whereas the tooth crown heights of the 45,X/46,XX females were close to those of the normal control females. The differences between the 45,X and 45,X/46,XX females were statistically significant, excluding the upper incisor area and a few teeth in the mandible. CONCLUSIONS: The effect of the sex chromosome deficiency on permanent tooth crown height is due to the magnitude of lacking sex chromosome material. The present results regarding the 45,X females are parallel to previous findings in Turner patients regarding reduced mesiodistal and labiolingual dimensions and tooth crown heights in the permanent dentition.

Root lengths in the permanent teeth of 45,X females.

OBJECTIVE: Studies in permanent and deciduous tooth crowns and permanent tooth roots in individuals with sex chromosome anomalies and in their relatives have given proof that the X chromosome affects enamel formation, root length and crown and root morphology. The present research studies the effects of sex chromosome deficiency on the development of permanent tooth root. MATERIALS AND METHODS: This research investigated tooth root lengths in a group of 97 45,X females. As controls there were 32 sisters and 28 mothers of the 45,X females, 45 female and 42 male population controls and 15 45,X/46,XX females from the KVANTTI research project. Tooth root lengths on both sides of the jaws were measured from panoramic radiographs in each acceptable instance. RESULTS: The results showed significantly shorter tooth root lengths in the 45,X females than in the female and male controls in all teeth measured, whereas in the female relatives tooth root lengths were shifted towards the aneuploids in relation to that in the general population. The tooth root lengths in the 45,X females differed more from those found in their sisters than in their mothers. CONCLUSIONS: These results with the large pure sample size of the whole dentitions in patients with monosomy X confirm the earlier findings of short tooth roots in 45,X females. The fact that in most instances there were no significant differences in tooth root lengths between 45,X and 45,X/46,XX females comes close to the earlier findings regarding mesio-distal tooth crown sizes.