Detalhe da pesquisa
1.
BCI-215, a Dual-Specificity Phosphatase Inhibitor, Reduces UVB-Induced Pigmentation in Human Skin by Activating Mitogen-Activated Protein Kinase Pathways.
Molecules
; 27(17)2022 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36080217
2.
Antioxidative and anti-inflammatory activity of psiguadial B and its halogenated analogues as potential neuroprotective agents.
Bioorg Chem
; 113: 105027, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34098398
3.
Asymmetric Total Synthesis of (+)-(3E)-Pinnatifidenyne via Abnormally Regioselective Pd(0)-Catalyzed Endocyclization.
J Org Chem
; 83(4): 1997-2005, 2018 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29327583
4.
Conformation-Enabled Total Syntheses of Ohmyungsamycinsâ A and B and Structural Revision of Ohmyungsamycinâ B.
Angew Chem Int Ed Engl
; 57(12): 3069-3073, 2018 03 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29380472
5.
Asymmetric synthesis of vinylogous ß-amino acids and their incorporation into mixed backbone oligomers.
Org Biomol Chem
; 15(15): 3255-3264, 2017 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28346549
6.
Identification of a novel circadian clock modulator controlling BMAL1 expression through a ROR/REV-ERB-response element-dependent mechanism.
Biochem Biophys Res Commun
; 469(3): 580-6, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26692477
7.
Identification and Structural Analysis of New Nrf2 Activators by Mechanism-Based Chemical Transformation of 15-Deoxy-Δ12, 14 -PGJ2.
Chembiochem
; 17(20): 1900-1904, 2016 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27453569
8.
Divergent synthetic route to new cyclopenta[c]pyran iridoids: syntheses of jatamanin A, F, G and J, gastrolactone and nepetalactone.
Org Biomol Chem
; 14(4): 1244-51, 2016 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26647357
9.
Diastereoselective Total Synthesis of (-)-Galiellalactone.
J Org Chem
; 80(24): 12193-200, 2015 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26544529
10.
Identification of small molecule inhibitors of the STAT3 signaling pathway: Insights into their structural features and mode of action.
Bioorg Med Chem Lett
; 25(22): 5444-8, 2015 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26392052
11.
Fine tuning of 4,6-bisphenyl-2-(3-alkoxyanilino)pyrimidine focusing on the activity-sensitive aminoalkoxy moiety for a therapeutically useful inhibitor of receptor for advanced glycation end products (RAGE).
Bioorg Med Chem
; 23(3): 579-87, 2015 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25533401
12.
Design and synthesis of a macrosphelide A-biotin chimera.
Org Biomol Chem
; 12(36): 7127-35, 2014 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25098405
13.
Photocatalytic intermolecular bromonitroalkylation of styrenes: synthesis of cyclopropylamine derivatives and their evaluation as LSD1 inhibitors.
RSC Adv
; 14(2): 831-835, 2024 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38174236
14.
Degrader-Antibody Conjugates: Emerging New Modality.
J Med Chem
; 66(1): 140-148, 2023 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36580273
15.
Thio(seleno)cyano-difluoroalkylation of Alkenes Using Visible-Light Photocatalysis.
Org Lett
; 25(19): 3564-3567, 2023 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37155717
16.
A bioisosteric approach to the discovery of novel N-aryl-N'-[4-(aryloxy)cyclohexyl]squaramide-based activators of eukaryotic initiation factor 2 alpha (eIF2α) phosphorylation.
Eur J Med Chem
; 239: 114501, 2022 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35716517
17.
Design, synthesis and insight into the structure-activity relationship of 1,3-disubstituted indazoles as novel HIF-1 inhibitors.
Bioorg Med Chem Lett
; 21(21): 6297-300, 2011 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21937231
18.
Targeting the Nuclear Receptor-Binding SET Domain Family of Histone Lysine Methyltransferases for Cancer Therapy: Recent Progress and Perspectives.
J Med Chem
; 64(20): 14913-14929, 2021 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34488340
19.
Physical and Functional Analysis of the Putative Rpn13 Inhibitor RA190.
Cell Chem Biol
; 27(11): 1371-1382.e6, 2020 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32857985
20.
Targeting Peroxisome Proliferator-Activated Receptor Delta (PPARδ): A Medicinal Chemistry Perspective.
J Med Chem
; 63(18): 10109-10134, 2020 09 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32539376