Detalhe da pesquisa
1.
Engineering a therapeutic lectin by uncoupling mitogenicity from antiviral activity.
Cell
; 163(3): 746-58, 2015 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26496612
2.
Synthesis and Thermodynamic Evaluation of Sialyl-Tn MUC1 Glycopeptides Binding to Macrophage Galactose-Type Lectin.
Chembiochem
; : e202400391, 2024 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38877657
3.
Targeting osteoarthritis-associated galectins and an induced effector class by a ditopic bifunctional reagent: Impact of its glycan part on binding measured in the tissue context.
Bioorg Med Chem
; 75: 117068, 2022 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36327696
4.
The glycobiology of the CD system: a dictionary for translating marker designations into glycan/lectin structure and function.
Trends Biochem Sci
; 40(7): 360-76, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25981696
5.
Bioactive cell-like hybrids coassembled from (glyco)dendrimersomes with bacterial membranes.
Proc Natl Acad Sci U S A
; 113(9): E1134-41, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26884210
6.
Onion-like glycodendrimersomes from sequence-defined Janus glycodendrimers and influence of architecture on reactivity to a lectin.
Proc Natl Acad Sci U S A
; 113(5): 1162-7, 2016 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26787853
7.
Galectin-1 Couples Glycobiology to Inflammation in Osteoarthritis through the Activation of an NF-κB-Regulated Gene Network.
J Immunol
; 196(4): 1910-21, 2016 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26792806
8.
Unraveling functional significance of natural variations of a human galectin by glycodendrimersomes with programmable glycan surface.
Proc Natl Acad Sci U S A
; 112(18): 5585-90, 2015 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25902539
9.
Galectin-related protein: An integral member of the network of chicken galectins: 2. From expression profiling to its immunocyto- and histochemical localization and application as tool for ligand detection.
Biochim Biophys Acta
; 1860(10): 2298-312, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27283907
10.
Teaming up synthetic chemistry and histochemistry for activity screening in galectin-directed inhibitor design.
Histochem Cell Biol
; 147(2): 285-301, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-28013366
11.
Direct Enzymatic Branch-End Extension of Glycocluster-Presented Glycans: An Effective Strategy for Programming Glycan Bioactivity.
Chemistry
; 23(7): 1623-1633, 2017 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-28035776
12.
Bivalent O-glycoside mimetics with S/disulfide/Se substitutions and aromatic core: Synthesis, molecular modeling and inhibitory activity on biomedically relevant lectins in assays of increasing physiological relevance.
Bioorg Med Chem
; 25(12): 3158-3170, 2017 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28483453
13.
Studying the Structural Significance of Galectin Design by Playing a Modular Puzzle: Homodimer Generation from Human Tandem-Repeat-Type (Heterodimeric) Galectin-8 by Domain Shuffling.
Molecules
; 22(9)2017 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28925965
14.
Detection of Proteome Changes in Human Colon Cancer Induced by Cell Surface Binding of Growth-Inhibitory Human Galectin-4 Using Quantitative SILAC-Based Proteomics.
J Proteome Res
; 15(12): 4412-4422, 2016 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27801591
15.
Galectin-8 enhances adhesion of multiple myeloma cells to vascular endothelium and is an adverse prognostic factor.
Glycobiology
; 26(10): 1048-1058, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27287437
16.
Intra- and intermolecular interactions of human galectin-3: assessment by full-assignment-based NMR.
Glycobiology
; 26(8): 888-903, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26911284
17.
Functional interplay between ganglioside GM1 and cross-linking galectin-1 induces axon-like neuritogenesis via integrin-based signaling and TRPC5-dependent Ca²âº influx.
J Neurochem
; 136(3): 550-63, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26526326
18.
Merging carbohydrate chemistry with lectin histochemistry to study inhibition of lectin binding by glycoclusters in the natural tissue context.
Histochem Cell Biol
; 145(2): 185-99, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26553286
19.
From lectin structure to functional glycomics: principles of the sugar code.
Trends Biochem Sci
; 36(6): 298-313, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21458998
20.
Thermodynamic Switch in Binding of Adhesion/Growth Regulatory Human Galectin-3 to Tumor-Associated TF Antigen (CD176) and MUC1 Glycopeptides.
Biochemistry
; 54(29): 4462-74, 2015 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26129647