Detalhe da pesquisa
1.
Understanding nucleotide-regulated FtsZ filament dynamics and the monomer assembly switch with large-scale atomistic simulations.
Biophys J
; 107(9): 2164-76, 2014 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-25418101
2.
Cyclostreptin derivatives specifically target cellular tubulin and further map the paclitaxel site.
Biochemistry
; 51(1): 329-41, 2012 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22148836
3.
[Should we add antiplatelet therapy to oral anticoagulation in patients with atrial fibrillation and vascular disease? Review of available evidence]. / Debe añadirse terapia antiagregante plaquetaria a la anticoagulación oral en los pacientes con fibrilación auricular y enfermedad vascular? Revisión de la evidencia disponible.
Arch Cardiol Mex
; 82(3): 248-51, 2012.
Artigo
em Espanhol
| MEDLINE | ID: mdl-23021363
4.
Modulation of microtubule interprotofilament interactions by modified taxanes.
Biophys J
; 101(12): 2970-80, 2011 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22208196
5.
Optimization of taxane binding to microtubules: binding affinity dissection and incremental construction of a high-affinity analog of paclitaxel.
Chem Biol
; 15(6): 573-85, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18559268
6.
Probing FtsZ and tubulin with C8-substituted GTP analogs reveals differences in their nucleotide binding sites.
Chem Biol
; 15(2): 189-99, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18291323
7.
Energetics and geometry of FtsZ polymers: nucleated self-assembly of single protofilaments.
Biophys J
; 94(5): 1796-806, 2008 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18024502
8.
Large scale purification of brain tubulin with the modified Weisenberg procedure.
Methods Mol Med
; 137: 17-28, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-18085219
9.
A Polymerization-Associated Structural Switch in FtsZ That Enables Treadmilling of Model Filaments.
mBio
; 8(3)2017 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28465423
10.
Triazolopyrimidines Are Microtubule-Stabilizing Agents that Bind the Vinca Inhibitor Site of Tubulin.
Cell Chem Biol
; 24(6): 737-750.e6, 2017 Jun 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28579361
11.
Polymerization of nucleotide-free, GDP- and GTP-bound cell division protein FtsZ: GDP makes the difference.
FEBS Lett
; 569(1-3): 43-8, 2004 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-15225606
12.
Endowing indole-based tubulin inhibitors with an anchor for derivatization: highly potent 3-substituted indolephenstatins and indoleisocombretastatins.
J Med Chem
; 56(7): 2813-27, 2013 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-23470139
13.
Septin C-terminal domain interactions: implications for filament stability and assembly.
Cell Biochem Biophys
; 62(2): 317-28, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22001952
14.
Insights into the interaction of discodermolide and docetaxel with tubulin. Mapping the binding sites of microtubule-stabilizing agents by using an integrated NMR and computational approach.
ACS Chem Biol
; 6(8): 789-99, 2011 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-21539341
15.
3-Hydroxyphenylpropionate and phenylpropionate are synergistic activators of the MhpR transcriptional regulator from Escherichia coli.
J Biol Chem
; 284(32): 21218-28, 2009 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-19520845
16.
The bound conformation of microtubule-stabilizing agents: NMR insights into the bioactive 3D structure of discodermolide and dictyostatin.
Chemistry
; 14(25): 7557-69, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18449868
17.
¿Debe añadirse terapia antiagregante plaquetaria a la anticoagulación oral en los pacientes con fibrilación auricular y enfermedad vascular? Revisión de la evidencia disponible / Should we add antiplatelet therapy to oral anticoagulation in patients with atrial fibrillation and vascular disease? Review of available evidence
Arch. cardiol. Méx
; 82(3): 248-251, jul.-sept. 2012. tab
Artigo
em Espanhol
| LILACS | ID: lil-685340
18.
The interactions of cell division protein FtsZ with guanine nucleotides.
J Biol Chem
; 282(52): 37515-28, 2007 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-17977836
19.
Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites.
Nat Chem Biol
; 3(2): 117-25, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17206139
20.
NMR determination of the bioactive conformation of peloruside A bound to microtubules.
J Am Chem Soc
; 128(27): 8757-65, 2006 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-16819869