Detalhe da pesquisa
1.
Somatic CAG expansion in Huntington's disease is dependent on the MLH3 endonuclease domain, which can be excluded via splice redirection.
Nucleic Acids Res
; 49(7): 3907-3918, 2021 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33751106
2.
Promotion of somatic CAG repeat expansion by Fan1 knock-out in Huntington's disease knock-in mice is blocked by Mlh1 knock-out.
Hum Mol Genet
; 29(18): 3044-3053, 2020 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32876667
3.
Patterns of CAG repeat instability in the central nervous system and periphery in Huntington's disease and in spinocerebellar ataxia type 1.
Hum Mol Genet
; 29(15): 2551-2567, 2020 08 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32761094
4.
Histone deacetylase knockouts modify transcription, CAG instability and nuclear pathology in Huntington disease mice.
Elife
; 92020 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32990597