Detalhe da pesquisa
1.
Quinolone derivatives containing strained spirocycle as orally active glycogen synthase kinase 3ß (GSK-3ß) inhibitors for type 2 diabetics.
Bioorg Med Chem
; 20(3): 1188-200, 2012 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22261023
2.
Discovery of BMS-986235/LAR-1219: A Potent Formyl Peptide Receptor 2 (FPR2) Selective Agonist for the Prevention of Heart Failure.
J Med Chem
; 63(17): 9003-9019, 2020 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32407089
3.
Synthesis and antibacterial activity of novel pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid derivatives carrying the 3-cyclopropylaminomethyl-4-substituted-1-pyrrolidinyl group as a C-10 substituent.
J Med Chem
; 51(11): 3238-49, 2008 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-18457383
4.
Synthesis and antibacterial activity of 1-(2-fluorovinyl)-7-substituted-4-quinolone-3-carboxylic acid derivatives, conformationally restricted analogues of fleroxacin.
J Med Chem
; 48(9): 3194-202, 2005 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-15857125
5.
Synthesis and antibacterial activity of the 4-quinolone-3-carboxylic acid derivatives having a trifluoromethyl group as a novel N-1 substituent.
J Med Chem
; 48(9): 3443-6, 2005 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-15857152
6.
Synthesis and structure-activity relationship studies of highly potent novel oxazolidinone antibacterials.
J Med Chem
; 51(20): 6558-62, 2008 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-18826297