A Review on Anti-urease Potential of Coumarins.

Coumarins, a heterocyclic benzo-α-pyrones and naturally occurring ring structure that possess significant pharmacological properties, have attracted the attention of researchers and medicinal chemists to reveal the suitability of both natural and synthetic coumarins as drugs. Many compounds have been synthesized utilizing the basic coumarin structure. The diverse synthetic methods resulted in the synthesis of important coumarin derivatives that offer a wide range of biological properties as antimicrobial, anticancer, anti-inflammatory, antioxidant, antidiabetic and antidepressant that make them potential drug candidates. With a particular interest in ulcers, coumarins have shown potential inhibition against urease enzyme. In recent years, scientists have emphasized the anti-urease activity of coumarins due to their low toxicity. The aim of this review is to compile data from recent research about anti-urease activities of coumarins and structure-activity relationship studies of the coumarin ring structure. Investigation of different structural substitutions in coumarin rings may help researchers to design new compounds with strong and effective anti- urease abilities.

High-yield synthesis of silver nanowires for transparent conducting PET films.

Silver nanowires (AgNWs) with ultrahigh purity and high yield were successfully synthesized by employing a modified facile polyol method using PVP as a capping and stabilizing agent. The reaction was carried out at a moderate temperature of 160 °C under mild stirring for about 3 h. The prepared AgNWs exhibited parallel alignment on a large scale and were characterized by UV-vis spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), and PL spectroscopy. The luminescent AgNWs exhibited red emission, which was accredited to deep holes. The SEM results confirmed the formation of AgNWs of 3.3 to 4.7 µm in length with an average diameter of about 86 nm, that is, the aspect ratio values of the AgNWs exceeded 45. An ink consisting of hydroxyethyl cellulose (HEC) and AgNWs was transferred to polyethylene terephthalate (PET) films by simple mechanical pressing. The PET films retained transparency and flexibility after the ink coating. The maximum transmittance value of as-prepared PET films in the visible region was estimated to be about 92.5% with a sheet resistance value of ca. 20 Ω/sq. This makes the films a potential substitute to commonly used expensive indium tin oxide (ITO) in the field of flexible optoelectronics.