Pesquisa | Portal de Pesquisa da BVS

1.

Designer proteins to trigger cell death.

Fairbrother, Wayne J; Ashkenazi, Avi.

Cell ; 157(7): 1506-8, 2014 Jun 19.

Artigo em Inglês | MEDLINE | ID: mdl-24949963

2.

Regulated cell death: signaling and mechanisms.

Ashkenazi, Avi; Salvesen, Guy.

Annu Rev Cell Dev Biol ; 30: 337-56, 2014.

Artigo em Inglês | MEDLINE | ID: mdl-25150011

3.

NEMO and RIP1 control cell fate in response to extensive DNA damage via TNF-α feedforward signaling.

Biton, Sharon; Ashkenazi, Avi.

Cell ; 145(1): 92-103, 2011 Apr 01.

Artigo em Inglês | MEDLINE | ID: mdl-21458669

4.

Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate.

Chang, Tsun-Kai; Lawrence, David A; Lu, Min; Tan, Jenille; Harnoss, Jonathan M; Marsters, Scot A; Liu, Peter; Sandoval, Wendy; Martin, Scott E; Ashkenazi, Avi.

Mol Cell ; 71(4): 629-636.e5, 2018 08 16.

Artigo em Inglês | MEDLINE | ID: mdl-30118681

5.

Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling.

Jin, Zhaoyu; Li, Yun; Pitti, Robert; Lawrence, David; Pham, Victoria C; Lill, Jennie R; Ashkenazi, Avi.

Cell ; 137(4): 721-35, 2009 May 15.

Artigo em Inglês | MEDLINE | ID: mdl-19427028

6.

E-cadherin couples death receptors to the cytoskeleton to regulate apoptosis.

Lu, Min; Marsters, Scot; Ye, Xiaofen; Luis, Elizabeth; Gonzalez, Lino; Ashkenazi, Avi.

Mol Cell ; 54(6): 987-998, 2014 Jun 19.

Artigo em Inglês | MEDLINE | ID: mdl-24882208

7.

Disruption of IRE1α through its kinase domain attenuates multiple myeloma.

Harnoss, Jonathan M; Le Thomas, Adrien; Shemorry, Anna; Marsters, Scot A; Lawrence, David A; Lu, Min; Chen, Yung-Chia Ariel; Qing, Jing; Totpal, Klara; Kan, David; Segal, Ehud; Merchant, Mark; Reichelt, Mike; Ackerly Wallweber, Heidi; Wang, Weiru; Clark, Kevin; Kaufman, Susan; Beresini, Maureen H; Laing, Steven T; Sandoval, Wendy; Lorenzo, Maria; Wu, Jiansheng; Ly, Justin; De Bruyn, Tom; Heidersbach, Amy; Haley, Benjamin; Gogineni, Alvin; Weimer, Robby M; Lee, Dong; Braun, Marie-Gabrielle; Rudolph, Joachim; VanWyngarden, Michael J; Sherbenou, Daniel W; Gomez-Bougie, Patricia; Amiot, Martine; Acosta-Alvear, Diego; Walter, Peter; Ashkenazi, Avi.

Proc Natl Acad Sci U S A ; 116(33): 16420-16429, 2019 08 13.

Artigo em Inglês | MEDLINE | ID: mdl-31371506

8.

Death receptor signal transducers: nodes of coordination in immune signaling networks.

Wilson, Nicholas S; Dixit, Vishva; Ashkenazi, Avi.

Nat Immunol ; 10(4): 348-55, 2009 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-19295631

9.

Snapshot: caspases.

Salvesen, Guy S; Ashkenazi, Avi.

Cell ; 147(2): 476-476.e1, 2011 Oct 14.

Artigo em Inglês | MEDLINE | ID: mdl-22000022

10.

Is SIRT2 required for necroptosis?

Newton, Kim; Hildebrand, Joanne M; Shen, Zhirong; Rodriguez, Diego; Alvarez-Diaz, Silvia; Petersen, Sean; Shah, Saumil; Dugger, Debra L; Huang, Chunzi; Auwerx, Johan; Vandenabeele, Peter; Green, Douglas R; Ashkenazi, Avi; Dixit, Vishva M; Kaiser, William J; Strasser, Andreas; Degterev, Alexei; Silke, John.

Nature ; 506(7489): E4-6, 2014 Feb 27.

Artigo em Inglês | MEDLINE | ID: mdl-24572428

11.

TRAF2 Sets a threshold for extrinsic apoptosis by tagging caspase-8 with a ubiquitin shutoff timer.

Gonzalvez, Francois; Lawrence, David; Yang, Becky; Yee, Sharon; Pitti, Robert; Marsters, Scot; Pham, Victoria C; Stephan, Jean-Philippe; Lill, Jennie; Ashkenazi, Avi.

Mol Cell ; 48(6): 888-99, 2012 Dec 28.

Artigo em Inglês | MEDLINE | ID: mdl-23142077

12.

UNCovering the molecular machinery of dependence receptor signaling.

Bagri, Anil; Ashkenazi, Avi.

Mol Cell ; 40(6): 851-3, 2010 Dec 22.

Artigo em Inglês | MEDLINE | ID: mdl-21172648

13.

Uncovering a Dual Regulatory Role for Caspases During Endoplasmic Reticulum Stress-induced Cell Death.

Anania, Veronica G; Yu, Kebing; Gnad, Florian; Pferdehirt, Rebecca R; Li, Han; Ma, Taylur P; Jeon, Diana; Fortelny, Nikolaus; Forrest, William; Ashkenazi, Avi; Overall, Christopher M; Lill, Jennie R.

Mol Cell Proteomics ; 15(7): 2293-307, 2016 07.

Artigo em Inglês | MEDLINE | ID: mdl-27125827

14.

Enhancing the antitumor efficacy of a cell-surface death ligand by covalent membrane display.

Nair, Pradeep M; Flores, Heather; Gogineni, Alvin; Marsters, Scot; Lawrence, David A; Kelley, Robert F; Ngu, Hai; Sagolla, Meredith; Komuves, Laszlo; Bourgon, Richard; Settleman, Jeffrey; Ashkenazi, Avi.

Proc Natl Acad Sci U S A ; 112(18): 5679-84, 2015 May 05.

Artigo em Inglês | MEDLINE | ID: mdl-25902490

15.

Hemicrania continua may respond to repetitive sphenopalatine ganglion block: A case report.

Androulakis, X Michelle; Krebs, Kaitlin A; Ashkenazi, Avi.

Headache ; 56(3): 573-9, 2016 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-26926875

16.

The Sphenopalatine Ganglion: Anatomy, Pathophysiology, and Therapeutic Targeting in Headache.

Robbins, Matthew S; Robertson, Carrie E; Kaplan, Eugene; Ailani, Jessica; Charleston, Larry; Kuruvilla, Deena; Blumenfeld, Andrew; Berliner, Randall; Rosen, Noah L; Duarte, Robert; Vidwan, Jaskiran; Halker, Rashmi B; Gill, Nicole; Ashkenazi, Avi.

Headache ; 56(2): 240-58, 2016 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-26615983

17.

Inflammasome-dependent and -independent IL-18 production mediates immunity to the ISCOMATRIX adjuvant.

Wilson, Nicholas S; Duewell, Peter; Yang, Becky; Li, Yun; Marsters, Scot; Koernig, Sandra; Latz, Eicke; Maraskovsky, Eugene; Morelli, Adriana Baz; Schnurr, Max; Ashkenazi, Avi.

J Immunol ; 192(7): 3259-68, 2014 Apr 01.

Artigo em Inglês | MEDLINE | ID: mdl-24610009

18.

Trigger point injections for headache disorders: expert consensus methodology and narrative review.

Robbins, Matthew S; Kuruvilla, Deena; Blumenfeld, Andrew; Charleston, Larry; Sorrell, Michael; Robertson, Carrie E; Grosberg, Brian M; Bender, Steven D; Napchan, Uri; Ashkenazi, Avi.

Headache ; 54(9): 1441-59, 2014 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-25168295

19.

Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL.

Wagner, Klaus W; Punnoose, Elizabeth A; Januario, Thomas; Lawrence, David A; Pitti, Robert M; Lancaster, Kate; Lee, Dori; von Goetz, Melissa; Yee, Sharon Fong; Totpal, Klara; Huw, Ling; Katta, Viswanatham; Cavet, Guy; Hymowitz, Sarah G; Amler, Lukas; Ashkenazi, Avi.

Nat Med ; 13(9): 1070-7, 2007 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-17767167

20.

Host genetic background impacts modulation of the TLR4 pathway by RON in tissue-associated macrophages.

Chaudhuri, Amitabha; Wilson, Nicholas S; Yang, Becky; Paler Martinez, Andres; Liu, Jinfeng; Zhu, Catherine; Bricker, Nicole; Couto, Suzana; Modrusan, Zora; French, Dorothy; Cupp, James; Ashkenazi, Avi.

Immunol Cell Biol ; 91(7): 451-60, 2013 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-23817579

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