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Sci Rep ; 5: 12990, 2015 Aug 10.
Artigo em Inglês | MEDLINE | ID: mdl-26257370

RESUMO

Micronutrient deficiency is common in patients with HIV/AIDS, usually caused by mal-absorption and/or drug interactions. 25-hydroxyvitamin D is of fundamental importance for the homeostasis of musculoskeletal health. The current study aimed to evaluate the nutritional status of HIV-infected subjects in order to make their nutritional diagnoses, including their vitamin D blood levels, and to estimate their consumption of vitamin D. The study included 98 HIV-1-infected subjects, followed at University of São Paulo Medical School - HC-FMUSP. We performed a nutritional evaluation, along with the determination of patients' serum 25-hydroxyvitamin D and calcium concentration, biochemical analyses, and an anthropometric assessment. In the medical interview a 24-hour food recall was used (R24) to estimate daily calorie intake, macronutrients, calcium, and vitamin D. A high level of vitamin D deficiency was observed in our patients: 83.4% of them had levels below 30 ng/ml; they also presented an increased risk of cardiovascular disease, along with a high consumption of dietary fat. Factors related to the virus itself and to the use of antiretroviral drugs may have contributed for the low vitamin D levels seen in our HIV-1-infected patients.


Assuntos
Infecções por HIV/diagnóstico , Deficiência de Vitamina D/diagnóstico , Vitamina D/análogos & derivados , Adulto , Brasil , Cálcio/sangue , Doenças Cardiovasculares/etiologia , Estudos Transversais , Gorduras na Dieta , Feminino , Infecções por HIV/sangue , Infecções por HIV/complicações , Humanos , Entrevistas como Assunto , Masculino , Pessoa de Meia-Idade , Estado Nutricional , Sobrepeso , Fatores de Risco , Vitamina D/sangue , Deficiência de Vitamina D/complicações
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