Comparison of Hand Function Between Children With Type 1 Diabetes Mellitus and Children Without Type 1 Diabetes Mellitus.

PURPOSE: This study compared the hand function of children between the ages of 8 and 12 years with type 1 diabetes mellitus (T1DM) with that of children without diabetes. METHODS: The Modified Jebsen-Taylor Hand Function Test and the Purdue Pegboard Test were used to assess hand function. The Pediatric Quality of Life Inventory 4.0 was used for evaluating health-related quality of life. RESULTS: Duration of writing was found to be significantly longer on the dominant side of the T1DM group compared with the children without T1DM. The durations of card turning, moving large, light objects, and large, heavy objects on the nondominant side of the T1DM group were also found to be significantly longer than those in the children without T1DM. The total scale score of health-related quality of life was significantly lower in the T1DM group compared with the children without T1DM. CONCLUSIONS: T1DM affects hand function, particularly the dominant side for writing and nondominant side for card turning and moving large objects.

The Effects of Exercise Training on Physical Activity Level, Daily Living Activities, and Participation in Children with Hemophilia.

OBJECTIVE: Hemophilia is an uncommon disorder that is difficult to diagnose and manage. Effective movement and individual physiotherapy interventions can improve physical activity levels, quality of life, and participation in children with hemophilia. This study aimed to investigate the effects of individually planned exercise on joint health, functional level, pain, participation, and quality of life in children with hemophilia. MATERIALS AND METHODS: Twenty-nine children with hemophilia (aged 8-18 years) were randomized into either an exercise group with physiotherapists (n = 14) or a counseling home-exercise group (n = 15). Pain, range of motion, and strength were measured using a visual analog scale, goniometer, and digital dynamometer, respectively. Joint health, functional capacity, participation, quality of life, and physical activity were assessed using the Hemophilia Joint Health Status, 6-Minute Walk Test, Canadian Occupation Performance Measure, Pediatrics Quality of Life, and International Physical Activity Questionnaire, respectively. The exercises were planned individually according to the needs of both groups. Additionally, the exercise group performed the exercise with a physiotherapist. Interventions were performed 3 days/week for 8 weeks. RESULTS: The Hemophilia Joint Health Status, 6-Minute Walk Test, Canadian Occupation Performance Measure, International Physical Activity Questionnaire, muscle strength, and range of motion (elbow, knee, and ankle) were significantly improved in both groups (P < .05). Compared with the counseling home-exercise program group, the exercise group had better results in the 6-Minute Walk Test, muscle strength, and range of motion (knee and ankle flexion) (P < .05). No significant difference was found in pain and Pediatrics Quality of Life scores in both groups. CONCLUSION: Using individually planned exercise in children with hemophilia is an effective physiotherapy approach to improve physical activity, participation, functional level, and joint health.

Building a Lung and Ovarian Cancer Data Warehouse.

OBJECTIVES: Despite the collection of vast amounts of data by the healthcare sector, effective decision-making in medical practice is still challenging. Data warehousing technology can be applied for the collection and management of clinical data from various sources to provide meaningful insights for physicians and administrators. Cancer data are extremely complicated and massive; hence, a clinical data warehouse system can provide insights into prevention, diagnosis and treatment processes through the use of online analytical processing tools for the analysis of multi-dimensional data at different granularity levels. METHODS: In this study, a clinical data warehouse was developed for lung cancer data, which were kindly provided by the United States National Cancer Institute. Lung and ovarian cancer data were imported in specific formats and cleaned to remove errors and redundancies. SQL server integration services (SSIS) were used for the extract-transform-load (ETL) process. RESULTS: The design of the clinical data warehouse responds efficiently to all types of queries by adopting the fact constellation schema model. Various online analytical processing queries can be expressed using the proposed approach. CONCLUSIONS: This model succeeded in responding to complex queries, and the analysis of data is facilitated by using online analytical processing cubes and viewing multilevel data details.