RESUMO
Primary cutaneous diffuse large B-cell lymphoma, leg type (DLBCLLT) is a rare, intermediately aggressive form of primary cutaneous B-cell lymphoma (CBCL) that is characterized by the presence of large round cells on histopathology. Clinically, patients present with red-brown nodules on the distal legs. The prognosis is less favorable than other types of CBCLs, with a 5-year survival rate of 50%. We present a case of primary cutaneous DLBCLLT in a 74-year-old woman. A comprehensive review of cutaneous T-cell lymphoma and CBCL also is provided, along with a discussion of the T-cell and B-cell forms of pseudolymphoma.
Assuntos
Linfoma Difuso de Grandes Células B/tratamento farmacológico , Linfoma Difuso de Grandes Células B/patologia , Idoso , Feminino , Humanos , Perna (Membro)/patologia , Linfoma Difuso de Grandes Células B/diagnóstico , PrognósticoRESUMO
Fibrofolliculoma and trichodiscoma are adnexal tumors that arise from or around hair follicles and are two of the many characteristic features of Birt-Hogg-Dubé (BHD) syndrome. Fibrofolliculoma and other hair follicle hamartomas can be differentiated from their clinically indistinct counterparts (eg, trichodiscomas, trichoadenomas) by histologic and staining comparison. We report a rare case of a 54-year-old man who presented with a subcutaneous papule on the abdomen that was histologically proven to have features of both a solitary fibrofolliculoma and trichodiscoma.
Assuntos
Fibroma/diagnóstico , Folículo Piloso , Hamartoma/diagnóstico , Neoplasias Primárias Múltiplas/diagnóstico , Neoplasias Cutâneas/diagnóstico , Abdome , Diagnóstico Diferencial , Fibroma/complicações , Fibroma/patologia , Hamartoma/complicações , Hamartoma/patologia , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias Primárias Múltiplas/complicações , Neoplasias Primárias Múltiplas/patologia , Neoplasias Cutâneas/complicações , Neoplasias Cutâneas/patologiaAssuntos
Bimatoprost/efeitos adversos , Hiperpigmentação/induzido quimicamente , Iris/efeitos dos fármacos , Administração Tópica , Anti-Hipertensivos/administração & dosagem , Anti-Hipertensivos/efeitos adversos , Bimatoprost/administração & dosagem , Pestanas/efeitos dos fármacos , Feminino , Humanos , Pessoa de Meia-Idade , Soluções OftálmicasRESUMO
BACKGROUND: Epidermal nevus syndrome is a multi-system disease with a wide spectrum of clinical presentation. Numerous specialists may be required to address its extra cutaneous manifestations. MAIN OBSERVATIONS: We report a severe case of epidermal nevus syndrome involving the oral cavity, pharynx, and central nervous system in addition to disfiguring skin lesions. CONCLUSIONS: Dermatologists are in a unique position to first render the diagnosis of epidermal nevus syndrome for young patients and ensure appropriate follow-up.