Pesquisa | Portal de Pesquisa da BVS

1.

AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias.

Sykes, Stephen M; Lane, Steven W; Bullinger, Lars; Kalaitzidis, Demetrios; Yusuf, Rushdia; Saez, Borja; Ferraro, Francesca; Mercier, Francois; Singh, Harshabad; Brumme, Kristina M; Acharya, Sanket S; Scholl, Claudia; Schöll, Claudia; Tothova, Zuzana; Attar, Eyal C; Fröhling, Stefan; DePinho, Ronald A; Armstrong, Scott A; Gilliland, D Gary; Scadden, David T.

Cell ; 146(5): 697-708, 2011 Sep 02.

Artigo em Inglês | MEDLINE | ID: mdl-21884932

2.

Ivosidenib induces deep durable remissions in patients with newly diagnosed IDH1-mutant acute myeloid leukemia.

Roboz, Gail J; DiNardo, Courtney D; Stein, Eytan M; de Botton, Stéphane; Mims, Alice S; Prince, Gabrielle T; Altman, Jessica K; Arellano, Martha L; Donnellan, Will; Erba, Harry P; Mannis, Gabriel N; Pollyea, Daniel A; Stein, Anthony S; Uy, Geoffrey L; Watts, Justin M; Fathi, Amir T; Kantarjian, Hagop M; Tallman, Martin S; Choe, Sung; Dai, David; Fan, Bin; Wang, Hongfang; Zhang, Vickie; Yen, Katharine E; Kapsalis, Stephanie M; Hickman, Denice; Liu, Hua; Agresta, Samuel V; Wu, Bin; Attar, Eyal C; Stone, Richard M.

Blood ; 135(7): 463-471, 2020 02 13.

Artigo em Inglês | MEDLINE | ID: mdl-31841594

3.

Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML.

DiNardo, Courtney D; Stein, Eytan M; de Botton, Stéphane; Roboz, Gail J; Altman, Jessica K; Mims, Alice S; Swords, Ronan; Collins, Robert H; Mannis, Gabriel N; Pollyea, Daniel A; Donnellan, Will; Fathi, Amir T; Pigneux, Arnaud; Erba, Harry P; Prince, Gabrielle T; Stein, Anthony S; Uy, Geoffrey L; Foran, James M; Traer, Elie; Stuart, Robert K; Arellano, Martha L; Slack, James L; Sekeres, Mikkael A; Willekens, Christophe; Choe, Sung; Wang, Hongfang; Zhang, Vickie; Yen, Katharine E; Kapsalis, Stephanie M; Yang, Hua; Dai, David; Fan, Bin; Goldwasser, Meredith; Liu, Hua; Agresta, Sam; Wu, Bin; Attar, Eyal C; Tallman, Martin S; Stone, Richard M; Kantarjian, Hagop M.

N Engl J Med ; 378(25): 2386-2398, 2018 Jun 21.

Artigo em Inglês | MEDLINE | ID: mdl-29860938

4.

Molecular remission and response patterns in patients with mutant-IDH2 acute myeloid leukemia treated with enasidenib.

Stein, Eytan M; DiNardo, Courtney D; Fathi, Amir T; Pollyea, Daniel A; Stone, Richard M; Altman, Jessica K; Roboz, Gail J; Patel, Manish R; Collins, Robert; Flinn, Ian W; Sekeres, Mikkael A; Stein, Anthony S; Kantarjian, Hagop M; Levine, Ross L; Vyas, Paresh; MacBeth, Kyle J; Tosolini, Alessandra; VanOostendorp, Jason; Xu, Qiang; Gupta, Ira; Lila, Thomas; Risueno, Alberto; Yen, Katharine E; Wu, Bin; Attar, Eyal C; Tallman, Martin S; de Botton, Stéphane.

Blood ; 133(7): 676-687, 2019 02 14.

Artigo em Inglês | MEDLINE | ID: mdl-30510081

5.

A phase 1 study of the antibody-drug conjugate brentuximab vedotin with re-induction chemotherapy in patients with CD30-expressing relapsed/refractory acute myeloid leukemia.

Narayan, Rupa; Blonquist, Traci M; Emadi, Ashkan; Hasserjian, Robert P; Burke, Meghan; Lescinskas, Christopher; Neuberg, Donna S; Brunner, Andrew M; Hobbs, Gabriela; Hock, Hanno; McAfee, Steven L; Chen, Yi-Bin; Attar, Eyal; Graubert, Timothy A; Bertoli, Christina; Moran, Jenna A; Bergeron, Meghan K; Foster, Julia E; Ramos, Aura Y; Som, Tina T; Vartanian, Megan K; Story, Jennifer L; McGregor, Kristin; Macrae, Molly; Behnan, Tanya; Wey, Margaret C; Rae, Jessica; Preffer, Frederic I; Lesho, Patricia; Duong, Vu H; Mann, Mason L; Ballen, Karen K; Connolly, Christine; Amrein, Philip C; Fathi, Amir T.

Cancer ; 126(6): 1264-1273, 2020 03 15.

Artigo em Inglês | MEDLINE | ID: mdl-31860140

6.

Isocitrate dehydrogenase 1 and 2 mutations, 2-hydroxyglutarate levels, and response to standard chemotherapy for patients with newly diagnosed acute myeloid leukemia.

Brunner, Andrew M; Neuberg, Donna S; Wander, Seth A; Sadrzadeh, Hossein; Ballen, Karen K; Amrein, Philip C; Attar, Eyal; Hobbs, Gabriela S; Chen, Yi-Bin; Perry, Ashley; Connolly, Christine; Joseph, Christelle; Burke, Meghan; Ramos, Aura; Galinsky, Ilene; Yen, Katharine; Yang, Hua; Straley, Kimberly; Agresta, Sam; Adamia, Sophia; Borger, Darrell R; Iafrate, Anthony; Graubert, Timothy A; Stone, Richard M; Fathi, Amir T.

Cancer ; 125(4): 541-549, 2019 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-30422308

7.

A phase I study of lenalidomide plus chemotherapy with mitoxantrone, etoposide, and cytarabine for the reinduction of patients with acute myeloid leukemia.

DeAngelo, Daniel J; Brunner, Andrew M; Werner, Lillian; Avigan, David; Fathi, Amir T; Sperling, Adam S; Washington, Abigail; Stroopinsky, Dina; Rosenblatt, Jacalyn; McMasters, Malgorzata; Luptakova, Katarina; Wadleigh, Martha; Steensma, David P; Hobbs, Gabriela S; Attar, Eyal C; Amrein, Philip C; Ebert, Benjamin L; Stone, Richard M; Ballen, Karen K.

Am J Hematol ; 93(2): 254-261, 2018 02.

Artigo em Inglês | MEDLINE | ID: mdl-29119643

8.

Phase I study of the aurora A kinase inhibitor alisertib with induction chemotherapy in patients with acute myeloid leukemia.

Fathi, Amir T; Wander, Seth A; Blonquist, Traci M; Brunner, Andrew M; Amrein, Philip C; Supko, Jeffrey; Hermance, Nicole M; Manning, Amity L; Sadrzadeh, Hossein; Ballen, Karen K; Attar, Eyal C; Graubert, Timothy A; Hobbs, Gabriela; Joseph, Christelle; Perry, Ashley M; Burke, Meghan; Silver, Regina; Foster, Julia; Bergeron, Meghan; Ramos, Aura Y; Som, Tina T; Fishman, Kaitlyn M; McGregor, Kristin L; Connolly, Christine; Neuberg, Donna S; Chen, Yi-Bin.

Haematologica ; 102(4): 719-727, 2017 04.

Artigo em Inglês | MEDLINE | ID: mdl-28034990

9.

Phase 2 study of intensified chemotherapy and allogeneic hematopoietic stem cell transplantation for older patients with acute lymphoblastic leukemia.

Fathi, Amir T; DeAngelo, Daniel J; Stevenson, Kristen E; Kolitz, Jonathan E; Asch, Julie D; Amrein, Philip C; Attar, Eyal C; Steensma, David P; Wadleigh, Martha; Foster, Julia; Connolly, Christine; Galinsky, Ilene; Devoe, Craig E; Stone, Richard M; Neuberg, Donna S; Ballen, Karen K.

Cancer ; 122(15): 2379-88, 2016 Aug 01.

Artigo em Inglês | MEDLINE | ID: mdl-27171984

10.

Health care utilization and end-of-life care for older patients with acute myeloid leukemia.

El-Jawahri, Areej R; Abel, Gregory A; Steensma, David P; LeBlanc, Thomas W; Fathi, Amir T; Graubert, Timothy A; DeAngelo, Daniel J; Wadleigh, Martha; Ballen, Karen K; Foster, Julia E; Attar, Eyal C; Amrein, Philip C; Brunner, Andrew M; Stone, Richard M; Temel, Jennifer S.

Cancer ; 121(16): 2840-8, 2015 Aug 15.

Artigo em Inglês | MEDLINE | ID: mdl-25926135

11.

Phase I study of urate oxidase in the reduction of acute graft-versus-host disease after myeloablative allogeneic stem cell transplantation.

Yeh, Albert C; Brunner, Andrew M; Spitzer, Thomas R; Chen, Yi-Bin; Coughlin, Erin; McAfee, Steven; Ballen, Karen; Attar, Eyal; Caron, Martin; Preffer, Frederic I; Yeap, Beow Y; Dey, Bimalangshu R.

Biol Blood Marrow Transplant ; 20(5): 730-4, 2014 May.

Artigo em Inglês | MEDLINE | ID: mdl-24530972

12.

Arsenic trioxide during consolidation for patients with previously untreated low/intermediate risk acute promyelocytic leukaemia may eliminate the need for maintenance therapy.

Coutre, Steven E; Othus, Megan; Powell, Bayard; Willman, Cheryl L; Stock, Wendy; Paietta, Elisabeth; Levitan, Denise; Wetzler, Meir; Attar, Eyal C; Altman, Jessica K; Gore, Steven D; Maher, Tracy; Kopecky, Kenneth J; Tallman, Martin S; Larson, Richard A; Appelbaum, Frederick R.

Br J Haematol ; 165(4): 497-503, 2014 May.

Artigo em Inglês | MEDLINE | ID: mdl-24528179

13.

Get out--and stay out.

Attar, Eyal C.

Blood ; 119(17): 3869-70, 2012 Apr 26.

Artigo em Inglês | MEDLINE | ID: mdl-22538491

14.

Prospective serial evaluation of 2-hydroxyglutarate, during treatment of newly diagnosed acute myeloid leukemia, to assess disease activity and therapeutic response.

Fathi, Amir T; Sadrzadeh, Hossein; Borger, Darrell R; Ballen, Karen K; Amrein, Philip C; Attar, Eyal C; Foster, Julia; Burke, Meghan; Lopez, Hector U; Matulis, Christina R; Edmonds, Katherine M; Iafrate, A John; Straley, Kimberly S; Yen, Katharine E; Agresta, Samuel; Schenkein, David P; Hill, Cedric; Emadi, Ashkan; Neuberg, Donna S; Stone, Richard M; Chen, Yi-Bin.

Blood ; 120(23): 4649-52, 2012 Nov 29.

Artigo em Inglês | MEDLINE | ID: mdl-23074281

15.

Engraftment syndrome after allogeneic hematopoietic cell transplantation in adults.

Omer, Aazim K; Kim, Haesook T; Yalamarti, Bhargavi; McAfee, Steven L; Dey, Bimalangshu R; Ballen, Karen K; Attar, Eyal; Chen, Yi-Bin; Spitzer, Thomas R.

Am J Hematol ; 89(7): 698-705, 2014 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-24668776

16.

Identification of RPS14 as a 5q- syndrome gene by RNA interference screen.

Ebert, Benjamin L; Pretz, Jennifer; Bosco, Jocelyn; Chang, Cindy Y; Tamayo, Pablo; Galili, Naomi; Raza, Azra; Root, David E; Attar, Eyal; Ellis, Steven R; Golub, Todd R.

Nature ; 451(7176): 335-9, 2008 Jan 17.

Artigo em Inglês | MEDLINE | ID: mdl-18202658

17.

Risk factors for invasive fungal disease after allogeneic hematopoietic stem cell transplantation: a single center experience.

Omer, Aazim K; Ziakas, Panayiotis D; Anagnostou, Theodora; Coughlin, Erin; Kourkoumpetis, Themistoklis; McAfee, Steven L; Dey, Bimalangshu R; Attar, Eyal; Chen, Yi-Bin; Spitzer, Thomas R; Mylonakis, Eleftherios; Ballen, Karen K.

Biol Blood Marrow Transplant ; 19(8): 1190-6, 2013 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-23747459

18.

Busulfan dose intensity and outcomes in reduced-intensity allogeneic peripheral blood stem cell transplantation for myelodysplastic syndrome or acute myeloid leukemia.

Chen, Yi-Bin; Coughlin, Erin; Kennedy, Kevin F; Alyea, Edwin P; Armand, Philippe; Attar, Eyal C; Ballen, Karen K; Cutler, Corey; Dey, Bimalangshu R; Koreth, John; McAfee, Steven L; Spitzer, Thomas R; Antin, Joseph H; Soiffer, Robert J; Ho, Vincent T.

Biol Blood Marrow Transplant ; 19(6): 981-7, 2013 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-23562738

19.

Coordinate loss of a microRNA and protein-coding gene cooperate in the pathogenesis of 5q- syndrome.

Kumar, Madhu S; Narla, Anupama; Nonami, Atsushi; Mullally, Ann; Dimitrova, Nadya; Ball, Brian; McAuley, J Randall; Poveromo, Luke; Kutok, Jeffrey L; Galili, Naomi; Raza, Azra; Attar, Eyal; Gilliland, D Gary; Jacks, Tyler; Ebert, Benjamin L.

Blood ; 118(17): 4666-73, 2011 Oct 27.

Artigo em Inglês | MEDLINE | ID: mdl-21873545

20.

Myelodysplastic syndromes: clinical practice guidelines in oncology.

Greenberg, Peter L; Attar, Eyal; Bennett, John M; Bloomfield, Clara D; Borate, Uma; De Castro, Carlos M; Deeg, H Joachim; Frankfurt, Olga; Gaensler, Karin; Garcia-Manero, Guillermo; Gore, Steven D; Head, David; Komrokji, Rami; Maness, Lori J; Millenson, Michael; O'Donnell, Margaret R; Shami, Paul J; Stein, Brady L; Stone, Richard M; Thompson, James E; Westervelt, Peter; Wheeler, Benton; Shead, Dorothy A; Naganuma, Maoko.

J Natl Compr Canc Netw ; 11(7): 838-74, 2013 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-23847220

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