Detalhe da pesquisa
1.
Functional characterization of a VEGF-A-targeting Anticalin, prototype of a novel therapeutic human protein class.
Angiogenesis
; 19(1): 79-94, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26650228
2.
Endotrophin, a Key Marker and Driver for Fibroinflammatory Disease.
Endocr Rev
; 2023 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38091968
3.
A highly selective humanized DDR1 mAb reverses immune exclusion by disrupting collagen fiber alignment in breast cancer.
J Immunother Cancer
; 11(6)2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37328286
4.
Neutrophil-derived leukotriene B4 is required for inflammatory arthritis.
J Exp Med
; 203(4): 837-42, 2006 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-16567388
5.
A novel role of prostaglandin E2 in neuropathic pain: blockade of microglial migration in the spinal cord.
Glia
; 59(2): 208-18, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21125641
6.
Microsomal prostaglandin E synthase-2 is not essential for in vivo prostaglandin E2 biosynthesis.
Prostaglandins Other Lipid Mediat
; 88(3-4): 73-81, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19010439
7.
Microsomal prostaglandin E synthase-1 is the central switch during immune-induced pyresis.
Nat Neurosci
; 6(11): 1137-8, 2003 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-14566340
8.
Sustained plasma hepcidin suppression and iron elevation by Anticalin-derived hepcidin antagonist in cynomolgus monkey.
Br J Pharmacol
; 175(7): 1054-1065, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29329501
9.
The role of prostaglandin E2 receptors in the pathogenesis of rheumatoid arthritis.
J Clin Invest
; 110(5): 651-8, 2002 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-12208866
10.
Deletion of the P2X7 nucleotide receptor reveals its regulatory roles in bone formation and resorption.
Mol Endocrinol
; 17(7): 1356-67, 2003 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12677010
11.
Inhibition of IL-1beta-dependent prostaglandin E2 release by antisense microsomal prostaglandin E synthase 1 oligonucleotides in A549 cells.
Mol Cell Endocrinol
; 205(1-2): 151-7, 2003 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-12890577
12.
First-in-human phase I study of PRS-050 (Angiocal), an Anticalin targeting and antagonizing VEGF-A, in patients with advanced solid tumors.
PLoS One
; 8(12): e83232, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24349470
13.
Evolution of anti-CD20 monoclonal antibody therapeutics in oncology.
MAbs
; 2(1): 14-9, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20081379
14.
The impact of microsomal prostaglandin e synthase 1 on blood pressure is determined by genetic background.
Hypertension
; 55(2): 531-8, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20065147
15.
Distinct expression profiles of Notch-1 protein in human solid tumors: Implications for development of targeted therapeutic monoclonal antibodies.
Biologics
; 4: 163-71, 2010 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-20631820
16.
Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors.
PLoS One
; 5(2): e9094, 2010 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-20161710
17.
Predominance of cyclooxygenase 1 over cyclooxygenase 2 in the generation of proinflammatory prostaglandins in autoantibody-driven K/BxN serum-transfer arthritis.
Arthritis Rheum
; 58(5): 1354-65, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18438856
18.
Prostacyclin antagonism reduces pain and inflammation in rodent models of hyperalgesia and chronic arthritis.
J Pharmacol Exp Ther
; 319(3): 1043-50, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16973887
19.
Prostaglandin E2 protects lower airways against bronchoconstriction.
Am J Physiol Lung Cell Mol Physiol
; 290(1): L105-13, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16113047
20.
COX-2-derived prostacyclin protects against bleomycin-induced pulmonary fibrosis.
Am J Physiol Lung Cell Mol Physiol
; 291(2): L144-56, 2006 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16473862