Stability indicating RP-HPLC method for simultaneous determination of piroxicam and ofloxacin in binary combination.

A simple and precise RP-HPLC method was developed for simultaneous determination of piroxicam and ofloxacin in pharmaceutical formulations and human serum. Optimum separations of piroxicam, ofloxacin and stress-induced degradation products were achieved by use of Hypersil BDS C8 column (250 x 4.6mm, 5 µm). The mobile phase was a mixture of acetonitrile: 0.012M K2HPO4: 0.008M sodium citrate (both buffers mixed and pH adjusted to 2.8) (50:25:25 v/v/v) delivered at flow rate of 1.5 mL min⁻¹ using DAD at 254 nm. Response was linear function of concentration over the ranges of 70-130 mg mL⁻¹ for piroxicam and ofloxacin (r² ≥ 0.999). The method efficiently separated the analytical peaks from degradation products with acceptable tailing and resolution. The developed method was successfully used for concurrent analysis of piroxicam and ofloxacin in pharmaceutical formulations, human serum and in vitro drug interaction studies.

Rubidium zinc trioxide perovskite materials for photovoltaic solar cell applications: A first principle calculations.

Perovskite materials are the well-known of solar cell applications and have excellent characteristics to study and explain the photocatalytic research. Exchange generalized gradient approximation (GGA) and Perdew-Burke-Ernzerhof-PBE correlation functionals and density functional theory (DFT)-based Cambridge Serial Total Energy Package (CASTEP) software are used to inspect the structural, electrical, mechanical, and the optical aspects of Zinc-based cubic perovskite RbZnO3. The compound is found to be in a stable cubic phase according to our study. The predicted elastic characteristics also satisfy the mechanical criterion for stability. Pugh's criterion indicates that RbZnO3 is brittle. The examination shows that the electronic band structure, RbZnO3 possesses an indirect bandgap (BG) that has 4.23eV. Findings of BG analysis agree with currently available evidence. Total and partial density of states (DOS) are used in the confirmation of degree of a localized electrons in special band. Optical transitions in compound are evaluated by adjusting damping ratio for the appropriate peaks of the notional dielectric functions. On one hand, the material is a semiconductor at absolute zero. On the other hand, the dielectric function's fictitious element dispersion illustrates the wide range of values for energy transparency. This substance might therefore be used in a solar cell to capture ultraviolet light.

Synergistic effects of ß-NaFeO2 ferrite nanoparticles for photocatalytic degradation, antibacterial, and antioxidant applications.

Here, synthesis and thorough characterization of ß-NaFeO2 nanoparticles utilizing a co-precipitation technique is presented. XRD analysis confirmed a hexagonal-phase structure of ß-NaFeO2. SEM revealed well-dispersed spherical nanoparticles with an average diameter of 45 nm. The FTIR spectrum analysis revealed weak adsorption bands at 1054 cm-1 suggested metal-metal bond stretching (Fe-Na). UV-Visible spectroscopy indicates a 4.4 eV optical band gap. Colloidal stability of ß-NaFeO2 was evidenced via Zeta potential (-28.5 mV) and Dynamic Light Scattering (DLS) measurements. BET analysis reveals a substantial 343.27 m2 g-1 surface area with mesoporous characteristics. Antioxidant analysis indicates efficacy comparable to standard antioxidants, while concentration-dependent antibacterial effects suggest enhanced efficacy against Gram-positive bacteria, particularly Streptococcus. The Photocatalytic activity of ß-NaFeO2 showed significant pollutant degradation (>90% efficiency), with increased degradation rates at higher nanoparticle concentrations, indicating potential for environmental remediation applications.

A dual-emitting Rhodamine B-encapsulated Zn-based MOF for the selective sensing of Chromium(VI).

A Rhodamine B-Zn-MOF composite (RhB-Zn-MOF) with dual emission intensity was synthesized through one pot synthesis by in-situ encapsulation of Rhodamine-B dye on a new Zn-MOF metal-organic framework [(Zn(OAc)2(4-BrIPh) (1,10-phenonthroline)(H2O)].H2O, (4-BrIPh = 4-Bromoisophthalic acid). The synthesized encapsulated material was characterized by elemental analysis, FTIR, UV-Visible spectroscopy, TGA, single crystal and powder X-ray diffraction and photoluminescence spectroscopy. The results showed that the synthesized composite, RhB-Zn-MOF could be used as an efficient probe for the selective sensing of Cr(VI) in the presence of Cr(III) as well as other metal ions.

Effect of Cd on Structural, Spectral, Morphological and Dielectric Properties of Sr1-xCdxZn2Fe4O11 R-type Hexaferrites Synthesized via Sol-gel Technique.

Sol-gel method was used to prepare Sr1-xCdxZn2Fe4O11 (x = 0.00, 0.02, 0.06, 0.1) R-type hexaferrite. The synthesized materials were sintered at 850oC and desired phase was obtained. X-ray diffraction analysis confirms that R-type hexaferrite exists only as a single phase. Using the Scherer formula, crystallite size for all of the prepared samples was found to be in the range of 10.39-12.62 nm. Crystallite size (D), the lattice parameters (a, c), and the cell volume (Vcell), d-spacing, bulk density, X-ray density, porosity, dislocation density and micro strain were determined in structural analysis. Fourier transform infrared spectroscopy method was used to identify the metal-oxygen vibrations at different locations. FT-IR verifies the presence of the Fe-O stretching vibration band at 743 and 867 cm-1. The typical grain size in surface morphology investigation ranges from 0.56 to 0.82 µm. Dielectric response of ferrite ceramic samples replaced with Cd2+ was investigated in the frequency range of 1 MHz-3 GHz. The AC conductivity rises with an increase in frequency because they are proportional to one another. This increasing tendency is effectively described by the theory of Maxwell-Wagner and Koop. Q-values remain constant as frequency rises and behaves independently of frequency as long as frequency reaches 1.7 GHz. These types of materials are utilized in high-frequency applications including frequency filters and resonant circuits. All of the magnetic properties determined by analyzing the M - H loops, including saturation magnetization (Ms), retentivity (Mr), and coercivity (Hc), exhibit an increasing trend as the substitution of Cd2+ rises. Ms (49.76-56.38 emu/g), Mr (15.82-18.30 emu/g) and Hc range from 203.20 Oe to 215.80 Oe. Grain size decreases cause arise in coercivity, which is caused by an enhancement in magneto-crystalline anisotropy. Overall results suggest that Cd2+ replaced R-type hexagonal ferrites are a great resource for longitudinal recording media; they have the potential to be used in a wide variety of electronic applications, including resonant circuits and high-frequency filters, security, detecting and switching.

Investigation of ultra wide bandgap Flouro-perovskite materials RBeF3 (R[bond, double bond]K and Li) for smart window applications: A DFT study.

The human body is affected by ultraviolet radiation because it can penetrate and harm bodily cells. Although skin cancer and early aging are consequences of prolonged exposure to ultraviolet (UV) rays, sun rays signify immediate excessive exposure. In this context, some structural, optical, electrical, and mechanical properties of the beryllium-based cubic fluoro-perovskite RBeF3 (R[bond, double bond]K and Li) compounds are examined through the use of density functional theory (DFT) within generalized gradient approximation (GGA) using the Perdew-Burke-Ernzerhof (PBE) approximations (GGA-PBE). The compounds KBeF3 and LiBeF3 have space group 221-pm3m, and their lattice constants and volumes are (3.765, 3.566) Å and (53.380, 45.379) Å3, respectively, based on their structural properties. Computed results indicate that the compounds' bandgaps are 7.35 eV and 7.12 eV, respectively, with an indirect nature for KBeF3 and LiBeF3. The properties of the band structure indicate that both compounds are insulators. The bonding properties of these compounds, RBeF3, are a combination of covalent and ionic. Optical properties of the compounds are examined which reflect the light-matter interaction like reflectivity, conductivity, and absorption. These materials were likely very hard but brittle, based on a higher bulk modulus B from elastic features, the B/G ratio, Pugh's ratio, and Vickers hardness. The compound RBeF3, as determined by the findings, is used as a UV protection and reflection layer for car and room windows.

The synergistic triad of graphene quantum dots, polymer, and ferrites for the photodegradation of dyes in aqueous solution.

This work aimed to investigate photocatalytic properties of GQDs@PEG@Mg-ZnFe2O4 nanocomposite, composed of graphene quantum dots (GQDs), polyethylene glycol (PEG), and Mg-ZnFe2O4, for the degradation of methylene blue (MB) and crystal violet (CV). This nanocomposite was synthesized using facile ultrasonics-assisted methodology. XRD analysis confirmed the formation of the spinel structure of the Mg-ZnFe2O4 in the nanocomposite, whereas the presence of GQDs and PEG was confirmed by Fourier transform infrared spectroscopy. Scanning electron microscopy (SEM) revealed a reduction in agglomeration and particle size in the ternary nanocomposite. The GQDs@PEG@Mg-ZnFe2O4 nanocomposite demonstrates a remarkable degradation efficiency of 98 % for CV and MB dyes in the presence of sunlight in 120 min, indicating its potential as an efficient photocatalyst. Vibrating sample magnetometer (VSM) analysis confirmed the superparamagnetic behavior of the GQDs@PEG@Mg-ZnFe2O4 nanocomposite which enables magnetic recovery of the photocatalyst after the degradation process. Overall, this study emphasizes the utilization of an environmentally friendly approach to effectively eliminate organic pollutants from wastewater, addressing a crucial environmental concern.

Investigation of structural, electronic, mechanical, & optical characteristics of Ra based-cubic hydrides RbRaX3 (X= F and cl) perovskite materials for solar cell applications: First principle study.

Perovskite materials are considered the gateway of various physical applications to meet the production and consumption of energy and medical fields. Density Functional Theory (DFT) becomes the most important field in the modern era to investigate perovskite materials for various physical properties. DFT nowadays is used to explore the perovskite materials for a lot of applications like photocatalytic, optoelectronic, and photovoltaics. We discussed radium based cubic hydrides RbRaX3 (while X = F & Cl) perovskite material's electrical, optical, elastic, & physical characteristics with the help of DFT-based CASTEP code with PBE exchange-correlation efficient of GGA. The RbRaF3 & RbRaCl3 have three-dimensional nature by means of space group 221 (Pm3 m). According to electronic characteristics, the direct bandgap of RbRaF3 RbRaCl3 are 3.18eV and 2.209eV, respectively. Both compounds are brittle in nature via Poisson's ratio & Pugh's criteria. Thus, our novel RbRaX3 (X = F and Cl) compounds have excellent applications for solar cell and medical areas.

Shape-control growth of 2D-In2Se3 with out-of-plane ferroelectricity by chemical vapor deposition.

For potential applications in ferroelectric switching and piezoelectric nano-generator devices, the promising ferroelectric properties of two dimensional (2D) layered In2Se3 attracted much attention. In the present study, 2D In2Se3 flakes down to monolayers are grown by the chemical vapor deposition (CVD) technique on a mica substrate with their structural, optical and ferroelectric properties being studied. The effect of growth parameters (time of growth and Ar flow rate) on the shape and size of the deposited flakes was studied. The optical microscopy study revealed that the flake changed from a circular shape to a sharp face triangle as the Ar flow rate and growth time increased. Raman spectroscopy and high-resolution scanning transmission electron microscopy (HR-STEM) studies revealed that the flakes were of α and ß phases, each of which has a hexagonal crystal structure. Strong second harmonic generation (SHG) was observed from α-In2Se3, demonstrating its non-centrosymmetric structure. The piezo-force microscopic (PFM) study showed the presence of out of plane (OOP) ferroelectricity with no in plane (IP) ferroelectricity in CVD grown α-In2Se3 indicating its vertically confined piezoresponse, which was tuned by the applied electric bias and the flake thickness. The present result of shape-controlled growth of In2Se3 with OOP ferroelectricity would open new pathways in the field of 2D ferroelectric switching devices.

Reversible Tuning of Ferromagnetism and Resistive Switching in ZnO/Cu Thin Films.

Systematic magnetic, electronic, and electrical studies on the Cu0.04Zn0.96O/Ga0.01Zn0.99O cell structure grown on (001) sapphire by the pulsed laser deposition technique show that the Cu multivalent (CuM+) ions modulate magnetic and resistive states of the cells. The magnetic moment is found to be reduced by ∼30% during the high resistance state (HRS) to low resistance state (LRS) switching. X-ray photoelectron spectroscopy results reveals an increase of the Cu+/Cu2+ oxidation state ratio (which has been determined by the relative positions of the Fermi level and the Cu acceptor level) during the HRS to LRS transition. This decreases the effective spin-polarized Cu2+-Vö-Cu+ channels and thus the magnetic moment. A conduction mechanism involving the formation of conductive filaments from the coupling of the CuM+ ions and Vö has been suggested.