Detalhe da pesquisa
1.
Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13.
Cell
; 170(2): 249-259.e25, 2017 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28669536
2.
Development of 2nd generation aminomethyl spectinomycins that overcome native efflux in Mycobacterium abscessus.
Proc Natl Acad Sci U S A
; 121(2): e2314101120, 2024 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38165935
3.
Mistranslation-associated perturbations of proteostasis do not promote accumulation of amyloid beta and plaque deposition in aged mouse brain.
Cell Mol Life Sci
; 80(12): 378, 2023 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38010524
4.
Apramycin Overcomes the Inherent Lack of Antimicrobial Bactericidal Activity in Mycobacterium abscessus.
Antimicrob Agents Chemother
; 66(2): e0151021, 2022 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34930031
5.
Phenotype of Mrps5-Associated Phylogenetic Polymorphisms Is Intimately Linked to Mitoribosomal Misreading.
Int J Mol Sci
; 23(8)2022 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35457201
6.
Mitochondrial Mistranslation in Brain Provokes a Metabolic Response Which Mitigates the Age-Associated Decline in Mitochondrial Gene Expression.
Int J Mol Sci
; 22(5)2021 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33803109
7.
Treatment of Nontuberculous Mycobacterial Pulmonary Disease: An Official ATS/ERS/ESCMID/IDSA Clinical Practice Guideline.
Clin Infect Dis
; 71(4): 905-913, 2020 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32797222
8.
Treatment of Nontuberculous Mycobacterial Pulmonary Disease: An Official ATS/ERS/ESCMID/IDSA Clinical Practice Guideline.
Clin Infect Dis
; 71(4): e1-e36, 2020 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32628747
9.
Stereocontrolled Synthesis of (-)-Bactobolin A.
J Am Chem Soc
; 142(16): 7306-7311, 2020 04 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32285674
10.
Apralogs: Apramycin 5-O-Glycosides and Ethers with Improved Antibacterial Activity and Ribosomal Selectivity and Reduced Susceptibility to the Aminoacyltranserferase (3)-IV Resistance Determinant.
J Am Chem Soc
; 142(1): 530-544, 2020 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31790244
11.
HIV Coinfection Is Associated with Low-Fitness rpoB Variants in Rifampicin-Resistant Mycobacterium tuberculosis.
Antimicrob Agents Chemother
; 64(10)2020 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32718966
12.
Natural Polymorphisms in Mycobacterium tuberculosis Conferring Resistance to Delamanid in Drug-Naive Patients.
Antimicrob Agents Chemother
; 64(11)2020 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32868333
13.
Treatment of nontuberculous mycobacterial pulmonary disease: an official ATS/ERS/ESCMID/IDSA clinical practice guideline.
Eur Respir J
; 56(1)2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32636299
14.
Evaluation of standardized automated rapid antimicrobial susceptibility testing of Enterobacterales-containing blood cultures: a proof-of-principle study.
J Antimicrob Chemother
; 75(11): 3218-3229, 2020 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32766760
15.
Tentative breakpoints and areas of technical uncertainty for early reading automated disc diffusion for Enterobacterales.
J Antimicrob Chemother
; 75(6): 1495-1505, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32155259
16.
Mutant MRPS5 affects mitoribosomal accuracy and confers stress-related behavioral alterations.
EMBO Rep
; 19(11)2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30237157
17.
Design, Multigram Synthesis, and in Vitro and in Vivo Evaluation of Propylamycin: A Semisynthetic 4,5-Deoxystreptamine Class Aminoglycoside for the Treatment of Drug-Resistant Enterobacteriaceae and Other Gram-Negative Pathogens.
J Am Chem Soc
; 141(12): 5051-5061, 2019 03 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30793894
18.
Whole-Genome Sequencing for Drug Resistance Profile Prediction in Mycobacterium tuberculosis.
Antimicrob Agents Chemother
; 63(4)2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30718257
19.
In vitro activity of apramycin against multidrug-, carbapenem- and aminoglycoside-resistant Enterobacteriaceae and Acinetobacter baumannii.
J Antimicrob Chemother
; 74(4): 944-952, 2019 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30629184
20.
Acquired Resistance to Bedaquiline and Delamanid in Therapy for Tuberculosis.
N Engl J Med
; 373(20): 1986-8, 2015 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26559594