Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 4 de 4
Filtrar
1.
Br J Anaesth ; 116(1): 70-6, 2016 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-26675951

RESUMO

BACKGROUND: Partial nephrectomy is performed with the aim to preserve renal function. But the occurrence of postoperative acute kidney injury (AKI) can interfere with this goal. Our primary aim was to evaluate associations between pre-specified modifiable factors and estimated glomerular filtration rate after partial nephrectomy. Our secondary aims were to evaluate associations between pre-specified modifiable factors and both serum creatinine concentration and type of nephrectomy. METHODS: The records of 1955 patients who underwent partial nephrectomy were collected. Postoperative estimated glomerular filtration rate (eGFR) was used as the primary outcome measure. Twenty modifiable risk factors were studied. A repeated-measures linear model with autoregressive within-subject correlation structure was used. The interaction between all the factors and type of nephrectomy was also studied. RESULTS: A total of 1187 (61%) patients had no kidney injury, 647 (33%) had stage I, 80 (4%) had stage II, and 41 (2%) had stage III injury. The mean eGFR increased an estimated 0.83 (99.76% CI 0.79-0.88) ml min(-1) 1.73 m(-2) for a unit increase in baseline eGFR. Mean eGFR was 2.65 (99.76% CI: 0.13, 5.18) ml min(-1) 1.73 m(-2) lower in patients with hypertension. Mean eGFR decreased 0.42 (99.76% CI: 0.22, 0.62) ml min(-1) 1.73 m(-2) for a 10-minute longer in duration of procedure and decreased 2.09 (99.76% CI: 1.39, 2.80) ml min(-1) 1.73 m(-2) for a 10-minute longer in ischemia time. It was 3.53 (99.76% CI: 0.83, 6.23) ml min(-1) 1.73 m(-2) lower for patients who received warm ischemia as compared to cold ischemia. CONCLUSION: Potentially modifiable factors associated with AKI in the postoperative period were identified as baseline renal function, preoperative hypertension, longer duration of surgical time and ischaemia time, and warm ischaemia.


Assuntos
Injúria Renal Aguda/epidemiologia , Injúria Renal Aguda/fisiopatologia , Rim/fisiopatologia , Rim/cirurgia , Período Perioperatório , Complicações Pós-Operatórias/epidemiologia , Creatinina/sangue , Feminino , Taxa de Filtração Glomerular/fisiologia , Humanos , Hipertensão/epidemiologia , Testes de Função Renal/estatística & dados numéricos , Masculino , Pessoa de Meia-Idade , Nefrectomia , Fatores de Risco , Índice de Gravidade de Doença , Fatores de Tempo , Isquemia Quente/estatística & dados numéricos
2.
Br J Anaesth ; 117(5): 671, 2016 11.
Artigo em Inglês | MEDLINE | ID: mdl-27799187

Assuntos
Neoplasias , Humanos
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA