RESUMO
A new Daphniphyllum alkaloid daphnicyclidin L (1), containing a rare cyclopentadienyl anion, which is stabilized as a zwitterion by an internal iminium counterion, was isolated from the stem barks of Daphniphyllum macropodum Miq., together with four known alkaloids: daphnicyclidin D (2), daphnicyclidin H (3), deoxyyuzurimine (4), and yuzurimine (5). The structures were elucidated on the basis of spectroscopic data. The configuration of 1 was elucidated by single-crystal X-ray diffraction crystallography.
Assuntos
Ciclopentanos/química , Magnoliopsida/metabolismo , Extratos Vegetais/química , Compostos Policíclicos/química , Alcaloides/química , Ânions , Cristalografia por Raios X , Etanol/química , Espectroscopia de Ressonância Magnética , Modelos Químicos , Modelos Moleculares , Nitrogênio/química , Plantas Medicinais/metabolismo , Espectrometria de Massas por Ionização por Electrospray , Espectrofotometria , Temperatura , Difração de Raios XRESUMO
OBJECTIVE: To study the chemical constituents of Bauhinia championii. METHOD: Compounds were isolated from the ethanolic extract of B. championii by silica gel column Chromatography, and their structures were elucidated by spectral analyses. RESULT: Five compounds were isolated and elucidated as 2,4,6-trimethoxyphenol 1-O-beta-D-(6'-O-galloyl)-glucopyranoside (1), (+/-)-lyoniresinol (2), daucosterol (3), beta-sitosterol (4) and gallic acid (5). CONCLUSION: Compounds 1-4 were isolated from B. championii for the first time.