Detalhe da pesquisa
1.
Dissection of a Down syndrome-associated trisomy to separate the gene dosage-dependent and -independent effects of an extra chromosome.
Hum Mol Genet
; 32(13): 2205-2218, 2023 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37014740
2.
Nrf2 amplifies oxidative stress via induction of Klf9.
Mol Cell
; 53(6): 916-928, 2014 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24613345
3.
Blockade of p38 kinase impedes the mobilization of protumorigenic myeloid populations to impact breast cancer metastasis.
Int J Cancer
; 147(8): 2279-2292, 2020 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32452014
4.
Internally ratiometric fluorescent sensors for evaluation of intracellular GTP levels and distribution.
Nat Methods
; 14(10): 1003-1009, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28869758
5.
TGF-ß signaling promotes tumor vasculature by enhancing the pericyte-endothelium association.
BMC Cancer
; 18(1): 670, 2018 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29921235
6.
A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers.
Cell Rep Med
; 5(3): 101434, 2024 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38387463
7.
WEE1 inhibition augments CDC7 (DDK) inhibitor-induced cell death in Ewing sarcoma by forcing premature mitotic entry and mitotic catastrophe.
Cancer Res Commun
; 2(6): 471-482, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36338546
8.
PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization.
Nat Med
; 8(10): 1145-52, 2002 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12244301
9.
Selective therapeutic strategy for p53-deficient cancer by targeting dysregulation in DNA repair.
Commun Biol
; 4(1): 862, 2021 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34253820
10.
TAK1 signaling regulates p53 through a mechanism involving ribosomal stress.
Sci Rep
; 10(1): 2517, 2020 02 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32054925
11.
Role of high-molecular weight tropomyosins in TGF-beta-mediated control of cell motility.
Int J Cancer
; 122(1): 78-90, 2008 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17721995
12.
Triplications of human chromosome 21 orthologous regions in mice result in expansion of megakaryocyte-erythroid progenitors and reduction of granulocyte-macrophage progenitors.
Oncotarget
; 9(4): 4773-4786, 2018 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29435140
13.
XBP1-KLF9 Axis Acts as a Molecular Rheostat to Control the Transition from Adaptive to Cytotoxic Unfolded Protein Response.
Cell Rep
; 25(1): 212-223.e4, 2018 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30282030
14.
A critical role of tropomyosins in TGF-beta regulation of the actin cytoskeleton and cell motility in epithelial cells.
Mol Biol Cell
; 15(10): 4682-94, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15317845
15.
Tumor-fibroblast interactions stimulate tumor vascularization by enhancing cytokine-driven production of MMP9 by tumor cells.
Oncotarget
; 8(22): 35592-35608, 2017 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28423685
16.
Tumor p38MAPK signaling enhances breast carcinoma vascularization and growth by promoting expression and deposition of pro-tumorigenic factors.
Oncotarget
; 8(37): 61969-61981, 2017 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28977919
17.
Silencing of the Tropomyosin-1 gene by DNA methylation alters tumor suppressor function of TGF-beta.
Oncogene
; 24(32): 5043-52, 2005 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-15897890
18.
Smad3-ATF3 signaling mediates TGF-beta suppression of genes encoding Phase II detoxifying proteins.
Free Radic Biol Med
; 38(3): 375-87, 2005 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15629866
19.
Truncating mutations in the ACVR2 gene attenuates activin signaling in prostate cancer cells.
Cancer Genet Cytogenet
; 163(2): 123-9, 2005 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16337854
20.
Integrin-ß5 and zyxin mediate formation of ventral stress fibers in response to transforming growth factor ß.
Cell Cycle
; 12(21): 3377-89, 2013 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24036928