Knowledge of Sexually Transmitted Infections amongst Pregnant Women Attending Antenatal Clinics in West Coast Region of The Gambia.

Sexually Transmitted Infections (STIs) during pregnancy remain a public health concern especially in developing countries including The Gambia. This study assessed the knowledge of STIs and its associated factors amongst pregnant women attending antenatal clinics in West Coast region of The Gambia. A descriptive cross-sectional study design was used. Two hundred and eighty pregnant women attending antenatal care in Brikama District Hospital, Brikama, and Bandung Maternity and Child Health Hospital, Bandung, who gave their consent, participated in this study. The instrument for data collection was an interviewer administered questionnaire. Data was analyzed using IBM SPSS for Windows, version 21.0. Level of significance was set at p < 0.05. All the respondents were aware of HIV/AIDS and their main source of information was from health care providers. However, most of them 263 (93.9%) had poor knowledge of STIs. Level of education (p < 0.001) and employment status (p = 0.001) had significant association with level of knowledge of STIs. This study also identified low level of education [AOR: 0.04 (95% CI: 0.01 - 0.35)], and unemployment [AOR: 21.97 (95% CI: 1.57 - 306.65)] as statistically significant predictors of low level of knowledge of STIs amongst the respondents. There is need for mass media campaigns and other public health measures aimed at increasing knowledge of STIs as this will herald effective intervention strategies towards the prevention of STIs.

Prevalence of sexually transmitted infections among pregnant women attending antenatal clinics in West Coast Region of The Gambia.

BACKGROUND: Sexually Transmitted Infections (STI) are the second most common cause of healthy life years lost by women in the 15 - 44 years age group in Africa. AIM/OBJECTIVE: To determine the prevalence of STIs among pregnant women attending antenatal care (ANC) clinics in the West Coast Region of The Gambia. MATERIALS AND METHODS: Blood, urine, and high vaginal swabs samples from 280 pregnant women attending ANC in Brikama District Hospital, Brikama, and Bandung Maternity and Child Health Hospital, Bandung were examined. Serum samples were tested for HIV using western blot technique and for syphilis using the Venereal Disease Research Laboratory (VDRL) test, and rapid plasma regimen. Candida albicans, Group B Streptococcus and Neisseria gonorrhoea were identified using Analytical Profile Index (API). Direct urine microscopy was used to identify C. albicans and Trichomonas vaginalis while Chlamydia trachomatis was identified using Direct Fluorescent Antibody (DFA) test. RESULTS: The overall prevalence of STIs was 53.6%. The pathogenic agents isolated were Candida albicans (31.8%), Streptococcus agalactiae (15.0%), Treponema pallidum (6.8%), HIV (5.7%), Trichomonas vaginalis (3.9%), Neisseria gonorrhoea (1.8%) and Chlamydia trachomatis (0.7%). STIs were more prevalent among women in the younger age group of 15 - 24 years (54.7%), unemployed (54.0%), Primipara (62.3%), and in the third trimester of pregnancy (72.7%). CONCLUSION: A high prevalence of STIs was found among pregnant women attending ANC in the West Coast region of The Gambia. Public health intervention programmes should be strengthened to promote the sexual and reproductive health of pregnant women in The Gambia.

Molecular Epidemiology of Group A Streptococcus Infections in The Gambia.

Molecular epidemiological data on Group A Streptococcus (GAS) infection in Africa is scarce. We characterized the emm-types and emm-clusters of 433 stored clinical GAS isolates from The Gambia collected between 2004 and 2018. To reduce the potential for strain mistyping, we used a newly published primer for emm-typing. There was considerable strain diversity, highlighting the need for vaccine development offering broad strain protection.