Detalhe da pesquisa
1.
A Phase I/II trial comparing autologous dendritic cell vaccine pulsed either with personalized peptides (PEP-DC) or with tumor lysate (OC-DC) in patients with advanced high-grade ovarian serous carcinoma.
J Transl Med
; 17(1): 391, 2019 11 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31771601
2.
Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells.
Nature
; 475(7355): 226-30, 2011 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-21753853
3.
Immunotherapy for ovarian cancer: recent advances and perspectives.
Curr Opin Oncol
; 26(5): 492-500, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25036883
4.
A Phase I vaccine trial using dendritic cells pulsed with autologous oxidized lysate for recurrent ovarian cancer.
J Transl Med
; 11: 149, 2013 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-23777306
5.
Development and Optimization of a GMP-Compliant Manufacturing Process for a Personalized Tumor Lysate Dendritic Cell Vaccine.
Vaccines (Basel)
; 8(1)2020 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31947581
6.
Personalized Dendritic Cell Vaccines-Recent Breakthroughs and Encouraging Clinical Results.
Front Immunol
; 10: 766, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31031762
7.
A Phase Ib Study of the Combination of Personalized Autologous Dendritic Cell Vaccine, Aspirin, and Standard of Care Adjuvant Chemotherapy Followed by Nivolumab for Resected Pancreatic Adenocarcinoma-A Proof of Antigen Discovery Feasibility in Three Patients.
Front Immunol
; 10: 1832, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31440238
8.
Activation of Notch1 signaling is required for beta-catenin-mediated human primary melanoma progression.
J Clin Invest
; 115(11): 3166-76, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16239965
9.
Role of vascular leukocytes in ovarian cancer neovascularization.
Adv Exp Med Biol
; 622: 273-80, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18546635
10.
Notch1 signaling promotes primary melanoma progression by activating mitogen-activated protein kinase/phosphatidylinositol 3-kinase-Akt pathways and up-regulating N-cadherin expression.
Cancer Res
; 66(8): 4182-90, 2006 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16618740
11.
Inhibition of endothelial cell proliferation by Notch1 signaling is mediated by repressing MAPK and PI3K/Akt pathways and requires MAML1.
FASEB J
; 20(7): 1009-11, 2006 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-16571776
12.
Local endothelial complement activation reverses endothelial quiescence, enabling t-cell homing, and tumor control during t-cell immunotherapy.
Oncoimmunology
; 6(9): e1326442, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28932632
13.
Potential approaches for more successful dendritic cell-based immunotherapy.
Expert Opin Biol Ther
; 15(4): 569-82, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25553913
14.
Ionizing radiation selectively reduces skin regulatory T cells and alters immune function.
PLoS One
; 9(6): e100800, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24959865
15.
Effect of solar particle event radiation on gastrointestinal tract bacterial translocation and immune activation.
Radiat Res
; 175(4): 485-92, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21294608
16.
Active Notch1 confers a transformed phenotype to primary human melanocytes.
Cancer Res
; 69(13): 5312-20, 2009 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19549918
17.
Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy.
Nat Med
; 14(1): 28-36, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18157142