Detalhe da pesquisa
1.
Alternative splicing as a regulator of development and tissue identity.
Nat Rev Mol Cell Biol
; 18(7): 437-451, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28488700
2.
Genome-wide DNA methylation and transcriptomic analysis of liver tissues subjected to early ischemia/reperfusion injury upon human liver transplantation.
Ann Hepatol
; 29(4): 101506, 2024 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38710471
3.
Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis.
EMBO J
; 37(11)2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29764981
4.
An LMNA synonymous variant associated with severe dilated cardiomyopathy: Case report.
Am J Med Genet A
; 188(2): 600-605, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34652067
5.
Thioridazine reverts the phenotype in cellular and Drosophila models of amyotrophic lateral sclerosis by enhancing TDP-43 aggregate clearance.
Neurobiol Dis
; 160: 105515, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34571136
6.
OTC intron 4 variations mediate pathogenic splicing patterns caused by the c.386G>A mutation in humans and spfash mice, and govern susceptibility to RNA-based therapies.
Mol Med
; 27(1): 157, 2021 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34906067
7.
Alternative splicing and liver disease.
Ann Hepatol
; 26: 100534, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34547477
8.
Autoregulation of TDP-43 mRNA levels involves interplay between transcription, splicing, and alternative polyA site selection.
Genes Dev
; 26(15): 1679-84, 2012 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22855830
9.
Point mutations in the N-terminal domain of transactive response DNA-binding protein 43 kDa (TDP-43) compromise its stability, dimerization, and functions.
J Biol Chem
; 292(28): 11992-12006, 2017 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28566288
10.
TDP-43 loss of cellular function through aggregation requires additional structural determinants beyond its C-terminal Q/N prion-like domain.
Hum Mol Genet
; 24(1): 9-20, 2015 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25122661
11.
Glial TDP-43 regulates axon wrapping, GluRIIA clustering and fly motility by autonomous and non-autonomous mechanisms.
Hum Mol Genet
; 24(21): 6134-45, 2015 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26276811
12.
TDP-43: gumming up neurons through protein-protein and protein-RNA interactions.
Trends Biochem Sci
; 37(6): 237-47, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22534659
13.
From transcriptomic to protein level changes in TDP-43 and FUS loss-of-function cell models.
Biochim Biophys Acta
; 1849(12): 1398-410, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26514432
14.
Predominance of spliceosomal complex formation over polyadenylation site selection in TDP-43 autoregulation.
Nucleic Acids Res
; 42(5): 3362-71, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24369426
15.
Functional characterization of the common c.-32-13T>G mutation of GAA gene: identification of potential therapeutic agents.
Nucleic Acids Res
; 42(2): 1291-302, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24150945
16.
A Novel Pathogenic BRCA1 Splicing Variant Produces Partial Intron Retention in the Mature Messenger RNA.
Int J Mol Sci
; 17(12)2016 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28009814
17.
Evolutionarily conserved heterogeneous nuclear ribonucleoprotein (hnRNP) A/B proteins functionally interact with human and Drosophila TAR DNA-binding protein 43 (TDP-43).
J Biol Chem
; 289(10): 7121-7130, 2014 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24492607
18.
Absence of TDP-43 is difficult to digest.
EMBO J
; 35(2): 115-7, 2016 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26702101
19.
TDP-43 regulates its mRNA levels through a negative feedback loop.
EMBO J
; 30(2): 277-88, 2011 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-21131904
20.
Characterizing TDP-43 interaction with its RNA targets.
Nucleic Acids Res
; 41(9): 5062-74, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23519609