Detalhe da pesquisa
1.
Tuning sterol extraction kinetics yields a renal-sparing polyene antifungal.
Nature
; 623(7989): 1079-1085, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37938782
2.
Outcomes by Candida spp. in the ReSTORE Phase 3 trial of rezafungin versus caspofungin for candidemia and/or invasive candidiasis.
Antimicrob Agents Chemother
; 68(5): e0158423, 2024 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38526046
3.
Rezafungin (CD101) demonstrates potent in vitro activity against Aspergillus, including azole-resistant Aspergillus fumigatus isolates and cryptic species.
J Antimicrob Chemother
; 73(11): 3063-3067, 2018 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30032217
4.
Time-Kill Kinetics of Rezafungin (CD101) in Vagina-Simulative Medium for Fluconazole-Susceptible and Fluconazole-Resistant Candida albicans and Non-albicans Candida Species.
Infect Dis Obstet Gynecol
; 2018: 7040498, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29681727
5.
Pharmacological Basis of CD101 Efficacy: Exposure Shape Matters.
Antimicrob Agents Chemother
; 61(11)2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28848022
6.
In vitro activity of the novel echinocandin CD101 at pH 7 and 4 against Candida spp. isolates from patients with vulvovaginal candidiasis.
J Antimicrob Chemother
; 72(5): 1355-1358, 2017 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28158577
7.
CD101: a novel long-acting echinocandin.
Cell Microbiol
; 18(9): 1308-16, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27354115
8.
Characterization of In Vitro Resistance Development to the Novel Echinocandin CD101 in Candida Species.
Antimicrob Agents Chemother
; 60(10): 6100-7, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27480852
9.
Preclinical Evaluation of the Stability, Safety, and Efficacy of CD101, a Novel Echinocandin.
Antimicrob Agents Chemother
; 60(11): 6872-6879, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27620474
10.
Activity of tedizolid phosphate (TR-701) in murine models of infection with penicillin-resistant and penicillin-sensitive Streptococcus pneumoniae.
Antimicrob Agents Chemother
; 56(9): 4713-7, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22713339
11.
In vitro activity and microbiological efficacy of tedizolid (TR-700) against Gram-positive clinical isolates from a phase 2 study of oral tedizolid phosphate (TR-701) in patients with complicated skin and skin structure infections.
Antimicrob Agents Chemother
; 56(9): 4608-13, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22687509
12.
Platensimycin is a selective FabF inhibitor with potent antibiotic properties.
Nature
; 441(7091): 358-61, 2006 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-16710421
13.
Results of the surveillance of Tedizolid activity and resistance program: in vitro susceptibility of gram-positive pathogens collected in 2011 and 2012 from the United States and Europe.
Diagn Microbiol Infect Dis
; 81(2): 112-8, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25488274
14.
Comparative in vitro activities of ertapenem against aerobic and facultative bacterial pathogens from patients with complicated skin and skin structure infections.
Diagn Microbiol Infect Dis
; 43(2): 129-33, 2002 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12088620
15.
In vivo efficacy of a novel oxazolidinone compound in two mouse models of infection.
Antimicrob Agents Chemother
; 51(9): 3434-6, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17606686
16.
Efficacy of caspofungin in the treatment of esophageal candidiasis resistant to fluconazole.
J Acquir Immune Defic Syndr
; 31(2): 183-7, 2002 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12394797