Detalhe da pesquisa
1.
Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease.
J Biol Chem
; 299(12): 105382, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37866628
2.
Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2.
bioRxiv
; 2024 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38798634
3.
Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM.
PLoS One
; 19(2): e0293548, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38359047
4.
Discovery of a Potent and Selective Naphthyridine-Based Chemical Probe for Casein Kinase 2.
ACS Med Chem Lett
; 14(4): 432-441, 2023 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37077385
5.
Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis.
Sci Rep
; 13(1): 6118, 2023 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37059819
6.
Fused Tetrahydroquinolines Are Interfering with Your Assay.
J Med Chem
; 66(21): 14434-14446, 2023 11 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37874947
7.
PROTAC Linkerology Leads to an Optimized Bivalent Chemical Degrader of Polycomb Repressive Complex 2 (PRC2) Components.
ACS Chem Biol
; 18(3): 494-507, 2023 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36877831
8.
Development of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic strategy for Alzheimer's disease.
bioRxiv
; 2023 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37292860
9.
Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin-dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology.
Elife
; 122023 07 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37490324
10.
Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology.
bioRxiv
; 2023 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37162893
11.
Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM.
bioRxiv
; 2023 Jul 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37547005