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1.
Mitochondrial DNA B Resour ; 8(6): 699-703, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37383606

RESUMO

Here, the complete chloroplast genome sequence of Zingiber teres is described using MGI paired-end sequencing. The genome is 163,428 bp in length and contains a small single-copy region (SSC) of 15,782 bp, a large single-copy region (LSC) of 88,142 bp, and two inverted repeat (IR) regions of 29,752 bp. The overall GC content is 36.1%, and the GC content of the IR regions is 41.1%, which is higher than that of both the LSC region (33.8%) and SSC region (29.5%). The genome of Z. teres contains 133 complete genes, including 88 protein-coding genes (79 protein-coding gene species), 38 tRNA genes (28 tRNA species), and 8 rRNA genes (four rRNA species). Maximum likelihood phylogenetic analysis yielded a well-resolved tree of the genus Zingiber, and Z. teres and Zingiber mioga were sister species in this tree. The development of DNA barcodes could aid the identification of Zingiber species.

2.
PhytoKeys ; 157: 137-144, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32934452

RESUMO

A new species, Petrocosmea nanchuanensis Z.Y. Liu, Z.Y. Li & Z.J. Qiu from Mt. Jinfo at Banhe valley of Nanchuan District in Chongqing Municipality (China) is described and illustrated for the first time. Even though this new species is similar to Petrocosmea barbata, it has several significant morphological differences, which includes smaller leaves, repand leaf margin, densely appressed longer pubescences on both surfaces of leaves, larger flower with length of its lower lips about three times longer than that of the upper lips, oblong lower lip lobes, shorter pistil, ovate anthers and styles that are shortly pubescent or approximately glabrous above the middle. The distinct features of P. nanchuanensis and four relative species namely, P. barbata, P. longipedicellata, P. cavaleriei and P. xanthomaculata were also represented in depth. However, P. nanchuanensis is most closely related to P. barbata, based on molecular studies.

3.
Curr Pharm Des ; 25(24): 2677-2693, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31333102

RESUMO

BACKGROUND: Nanopharmaceuticals have rapidly emerged as a means to cure several diseases. There are numerous reports describing the development and application of nanopharmaceuticals. Here, we discussed nanoparticle synthesis and the mechanisms to scavenge free radicals. We also discuss their major properties and list several commercially available nanomedicines. RESULTS: Reactive oxygen and hydrogen species are formed during normal metabolism, and excessive reactive species can damage proteins, lipids, and DNA and cause disease. Plant- and microbe-based nanoparticles, which can protect tissues from free radical damage, have recently gained research momentum because they are inexpensive and safe. CONCLUSION: Synthetic and biocompatible nanoparticles exhibit antioxidant, antidiabetic, anti-inflammatory, and anticancer properties, which can be used to treat several diseases. Further studies are needed to investigate their sizes, dose-dependent activities, and mechanisms of action.


Assuntos
Sequestradores de Radicais Livres/farmacologia , Nanomedicina/tendências , Nanopartículas
4.
J Zhejiang Univ Sci B ; 19(2): 85-119, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29405039

RESUMO

The aim of this review was to explore the pharmacological activity of early tracheophytes (pteridophytes) as an alternative medicine for treating human ailments. As the first vascular plants, pteridophytes (aka, ferns and fern allies) are an ancient lineage, and human beings have been exploring and using taxa from this lineage for over 2000 years because of their beneficial properties. We have documented the medicinal uses of pteridophytes belonging to thirty different families. The lycophyte Selaginella sp. was shown in earlier studies to have multiple pharmacological activity, such as antioxidant, anti-inflammatory, anti-cancer, antidiabetic, antiviral, antimicrobial, and anti-Alzheimer properties. Among all the pteridophytes examined, taxa from the Pteridaceae, Polypodiaceae, and Adiantaceae exhibited significant medicinal activity. Based on our review, many pteridophytes have properties that could be used in alternative medicine for treatment of various human illnesses. Biotechnological tools can be used to preserve and even improve their bioactive molecules for the preparation of medicines against illness. Even though several studies have reported medicinal uses of ferns, the possible bioactive compounds of several pteridophytes have not been identified. Furthermore, their optimal dosage level and treatment strategies still need to be determined. Finally, the future direction of pteridophyte research is discussed.


Assuntos
Fitoterapia , Traqueófitas , Anti-Infecciosos/farmacologia , Anti-Inflamatórios/farmacologia , Antineoplásicos Fitogênicos/farmacologia , Antioxidantes/farmacologia , Humanos , Compostos Fitoquímicos/análise , Compostos Fitoquímicos/farmacologia , Extratos Vegetais/farmacologia , Traqueófitas/química
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