Detalhe da pesquisa
1.
TGS1 impacts snRNA 3'-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration.
Nucleic Acids Res
; 50(21): 12400-12424, 2022 11 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35947650
2.
Intimate functional interactions between TGS1 and the Smn complex revealed by an analysis of the Drosophila eye development.
PLoS Genet
; 16(5): e1008815, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32453722
3.
WDR79/TCAB1 plays a conserved role in the control of locomotion and ameliorates phenotypic defects in SMA models.
Neurobiol Dis
; 105: 42-50, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28502804
4.
The S-adenosylmethionine analog sinefungin inhibits the trimethylguanosine synthase TGS1 to promote telomerase activity and telomere lengthening.
FEBS Lett
; 596(1): 42-52, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34817067
5.
Loss of Human TGS1 Hypermethylase Promotes Increased Telomerase RNA and Telomere Elongation.
Cell Rep
; 30(5): 1358-1372.e5, 2020 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32023455