Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 2 de 2
Filtrar
Mais filtros

Base de dados
Ano de publicação
Tipo de documento
Intervalo de ano de publicação
1.
Int J Pediatr Otorhinolaryngol ; 50(1): 15-22, 1999 Oct 15.
Artigo em Inglês | MEDLINE | ID: mdl-10596882

RESUMO

The decision to prescribe antibiotics post-tonsillectomy still remains controversial. However, recent changing trends in the tonsillar tissue microflora have been widely reported, with Haemophilus influenzae, Staphylococcus aureus and anaerobic organisms all being implicated. All of the above are beta-lactamase producers and thus render lactamase prone antibiotics inactive. We compared two groups of children, one on Amoxycillin and clavulanic acid (a lactamase stable antibiotic with anaerobic cover) for 1 week post tonsillectomy--Group A (N = 44), and another group on no treatment--Group B (N = 34). We compared tonsillar core, surface and postoperative tonsillar fossae bacteriological profiles in the two groups. The tonsil core pathogens included H. influenzae (64%) of which 9.5% were beta-lactamase producers, Streptococcus viridans (55.9%), S. aureus (37%) of which 86% were beta-lactamase producers, and anaerobes which were found in 25% of samples. We found that there was considerably less morbidity in those children receiving postoperative antibiotics compared to those who did not, as judged by the amount of analgesia consumed (p = 0.379), time to resumption of normal diet (p = 0.0072) and pain analogue scores (p = 0.0006). We feel that treating children who have undergone tonsillectomy with amoxycillin and clavulanic acid significantly reduces postoperative morbidity.


Assuntos
Amoxicilina/uso terapêutico , Antibacterianos/uso terapêutico , Antibioticoprofilaxia/métodos , Infecções Bacterianas/prevenção & controle , Ácido Clavulânico/uso terapêutico , Penicilinas/uso terapêutico , Tonsilectomia/métodos , Criança , Pré-Escolar , Quimioterapia Combinada , Seguimentos , Humanos , Cuidados Pós-Operatórios , Estudos Prospectivos , beta-Lactamases/biossíntese
2.
Libyan J Med ; 2(3): 111, 2007 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-21503205
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA