1.
Org Lett
; 22(14): 5685-5689, 2020 Jul 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32603130
RESUMO
The combination of SmI2 and the conjugate base of triethylurea (TEU-) has been shown to favor the cyclization of unsaturated halides over direct reduction to a much greater extent than other SmI2-based reductants. Aryl, heteroaryl, and alkyl halides (X = Br, Cl, F) readily undergo heterocyclization and carbocyclization in the presence of SmI2/TEU-.