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1.
Phys Rev Lett ; 129(25): 252701, 2022 Dec 16.
Artigo em Inglês | MEDLINE | ID: mdl-36608219

RESUMO

We present an improved measurement of the carbon-nitrogen-oxygen (CNO) solar neutrino interaction rate at Earth obtained with the complete Borexino Phase-III dataset. The measured rate, R_{CNO}=6.7_{-0.8}^{+2.0} counts/(day×100 tonnes), allows us to exclude the absence of the CNO signal with about 7σ C.L. The correspondent CNO neutrino flux is 6.6_{-0.9}^{+2.0}×10^{8} cm^{-2} s^{-1}, taking into account the neutrino flavor conversion. We use the new CNO measurement to evaluate the C and N abundances in the Sun with respect to the H abundance for the first time with solar neutrinos. Our result of N_{CN}=(5.78_{-1.00}^{+1.86})×10^{-4} displays a ∼2σ tension with the "low-metallicity" spectroscopic photospheric measurements. Furthermore, our result used together with the ^{7}Be and ^{8}B solar neutrino fluxes, also measured by Borexino, permits us to disfavor at 3.1σ C.L. the "low-metallicity" standard solar model B16-AGSS09met as an alternative to the "high-metallicity" standard solar model B16-GS98.

2.
Phys Rev Lett ; 128(9): 091803, 2022 Mar 04.
Artigo em Inglês | MEDLINE | ID: mdl-35302807

RESUMO

We report the measurement of sub-MeV solar neutrinos through the use of their associated Cherenkov radiation, performed with the Borexino detector at the Laboratori Nazionali del Gran Sasso. The measurement is achieved using a novel technique that correlates individual photon hits of events to the known position of the Sun. In an energy window between 0.54 to 0.74 MeV, selected using the dominant scintillation light, we have measured 10 887_{-2103}^{+2386}(stat)±947(syst) (68% confidence interval) solar neutrinos out of 19 904 total events. This corresponds to a ^{7}Be neutrino interaction rate of 51.6_{-12.5}^{+13.9} counts/(day·100 ton), which is in agreement with the standard solar model predictions and the previous spectroscopic results of Borexino. The no-neutrino hypothesis can be excluded with >5σ confidence level. For the first time, we have demonstrated the possibility of utilizing the directional Cherenkov information for sub-MeV solar neutrinos, in a large-scale, high light yield liquid scintillator detector. This measurement provides an experimental proof of principle for future hybrid event reconstruction using both Cherenkov and scintillation signatures simultaneously.

3.
Langmuir ; 32(19): 4736-45, 2016 05 17.
Artigo em Inglês | MEDLINE | ID: mdl-27077328

RESUMO

We investigate the dynamics of a droplet on a planar substrate as the droplet volume changes dynamically due to liquid being pumped in or out through a pore. We adopt a diffuse-interface formulation which is appropriately modified to account for a localized inflow-outflow boundary condition (the pore) at the bottom of the droplet, hence allowing to dynamically control its volume, as the droplet moves on a flat substrate with a periodic chemical pattern. We find that the droplet undergoes a stick-slip motion as the volume is increased (fattening droplet) which can be monitored by tracking the droplet contact points. If we then switch over to outflow conditions (thinning droplet), the droplet follows a different path (i.e., the distance of the droplet midpoint from the pore location evolves differently), giving rise to a hysteretic behavior. By means of geometrical arguments, we are able to theoretically construct the full bifurcation diagram of the droplet equilibria (positions and droplet shapes) as the droplet volume is changed, finding excellent agreement with time-dependent computations of our diffuse-interface model.

4.
Phys Rev Lett ; 115(23): 231802, 2015 Dec 04.
Artigo em Inglês | MEDLINE | ID: mdl-26684111

RESUMO

Borexino is a liquid scintillation detector located deep underground at the Laboratori Nazionali del Gran Sasso (LNGS, Italy). Thanks to the unmatched radio purity of the scintillator, and to the well understood detector response at low energy, a new limit on the stability of the electron for decay into a neutrino and a single monoenergetic photon was obtained. This new bound, τ≥6.6×10^{28} yr at 90% C.L., is 2 orders of magnitude better than the previous limit.

5.
Phys Rev Lett ; 108(5): 051302, 2012 Feb 03.
Artigo em Inglês | MEDLINE | ID: mdl-22400925

RESUMO

We observed, for the first time, solar neutrinos in the 1.0-1.5 MeV energy range. We determined the rate of pep solar neutrino interactions in Borexino to be 3.1±0.6{stat}±0.3{syst} counts/(day·100 ton). Assuming the pep neutrino flux predicted by the standard solar model, we obtained a constraint on the CNO solar neutrino interaction rate of <7.9 counts/(day·100 ton) (95% C.L.). The absence of the solar neutrino signal is disfavored at 99.97% C.L., while the absence of the pep signal is disfavored at 98% C.L. The necessary sensitivity was achieved by adopting data analysis techniques for the rejection of cosmogenic {11}C, the dominant background in the 1-2 MeV region. Assuming the Mikheyev-Smirnov-Wolfenstein large mixing angle solution to solar neutrino oscillations, these values correspond to solar neutrino fluxes of (1.6±0.3)×10{8} cm{-2} s^{-1} and <7.7×10{8} cm{-2} s{-1} (95% C.L.), respectively, in agreement with both the high and low metallicity standard solar models. These results represent the first direct evidence of the pep neutrino signal and the strongest constraint of the CNO solar neutrino flux to date.

6.
Phys Rev Lett ; 107(14): 141302, 2011 Sep 30.
Artigo em Inglês | MEDLINE | ID: mdl-22107184

RESUMO

The rate of neutrino-electron elastic scattering interactions from 862 keV (7)Be solar neutrinos in Borexino is determined to be 46.0±1.5(stat)(-1.6)(+1.5)(syst) counts/(day·100 ton). This corresponds to a ν(e)-equivalent (7)Be solar neutrino flux of (3.10±0.15)×10(9) cm(-2) s(-1) and, under the assumption of ν(e) transition to other active neutrino flavours, yields an electron neutrino survival probability of 0.51±0.07 at 862 keV. The no flavor change hypothesis is ruled out at 5.0 σ. A global solar neutrino analysis with free fluxes determines Φ(pp)=6.06(-0.06)(+0.02)×10(10) cm(-2) s(-1) and Φ(CNO)<1.3×10(9) cm(-2) s(-1) (95% C.L.). These results significantly improve the precision with which the Mikheyev-Smirnov-Wolfenstein large mixing angle neutrino oscillation model is experimentally tested at low energy.

7.
J Phys Chem B ; 112(12): 3693-704, 2008 Mar 27.
Artigo em Inglês | MEDLINE | ID: mdl-18314970

RESUMO

Dynamics of water absorption from a saturated vapor and water desorption into dry air for Nafion 1100 EW ionomers have been measured for film thicknesses between 51 and 606 microm and at temperatures ranging from 30 to 90 degrees C. Water absorption and desorption exhibit two distinct non-Fickian characteristics: (1) desorption is 10 times faster than absorption and (2) the normalized mass change does not collapse to a single master curve when plotted against time normalized by membrane thickness squared, t/l2, for either absorption or desorption. Water desorption data were fit well by a model in which diffusion is rapid and interfacial mass transport resistance is the rate-limiting process for water loss. Water absorption is described by a two-stage process. At early times, interfacial mass transport controls water absorption, and at longer times, water absorption is controlled by the dynamics of polymer swelling and relaxation.

8.
Rev Sci Instrum ; 78(10): 103904, 2007 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-17979432

RESUMO

An instrument for measuring the creep response of a material maintained under a controlled environment of temperature and vapor pressure is described. The temperature range of the instrument is 20-250 degrees C while the range of vapor pressure is 0-1 atm. Data are presented for tests conducted on this instrument with Nafion, a perfluorinated ionomer developed by DuPont and used as a membrane in polymer exchange membrane fuel cells, over a range of temperature and water vapor pressure. The data are useful for predicting long-term creep behavior of the material in the fuel cell environment as well as providing insight to molecular level interactions in the material as a function of temperature and hydration. Measurements including dynamic and equilibrium strain due to water uptake as well as elastic modulus are described. The main features of the instrument are presented along with experimental methodology and analysis of results. The adaptation of the instrument to other mechanical tests is briefly described.


Assuntos
Ambiente Controlado , Teste de Materiais/instrumentação , Micromanipulação/instrumentação , Elasticidade , Desenho de Equipamento , Análise de Falha de Equipamento , Teste de Materiais/métodos , Mecânica , Micromanipulação/métodos , Pressão , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Manejo de Espécimes/instrumentação , Manejo de Espécimes/métodos , Temperatura , Resistência à Tração
9.
Hum Pathol ; 12(8): 735-8, 1981 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-7026411

RESUMO

Two patients with primary amyloidosis, each of whom had received a renal transplant for chronic renal failure, developed amyloid in their allografts. In one patient amyloid was present primarily in glomeruli and to a lesser extent in the interstitial tissue. This patient developed renal failure necessitating retransplantation. In the second patient amyloid was seen in the interstitium and interlobular blood vessels. Minimal amyloid was present in the glomeruli. This patient died of cardiac amyloidosis with good graft function at the time of death. Of the several patients recorded in the literature with amyloid in renal allografts, our first patient is the only one to exhibit glomerular amyloid and failure of the graft. Amyloid in areas other than the glomerulus does not appear to be incompatible with satisfactory graft function.


Assuntos
Amiloidose/terapia , Transplante de Rim , Amiloide/metabolismo , Amiloidose/complicações , Feminino , Sobrevivência de Enxerto , Humanos , Falência Renal Crônica/complicações , Glomérulos Renais/análise , Masculino , Pessoa de Meia-Idade
10.
Surg Clin North Am ; 59(3): 471-82, 1979 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-451798

RESUMO

This represents an attempt to briefly outline the type of blood bank and transfusion service we at Montrose Memorial Hospital have developed and utilized to supply our blood needs. Basically it is a system based on a fairly large list of known, pretested, and available donors who can be contacted quickly to supply blood upon demand. Only bare minimum stock supplies are maintained. The major problem is waste of blood, but Montrose experience continues to fall below the average for rural areas. Although the starting and maintaining of this walking blood bank was and is a complicated involved, and somewhat tedious process, we have been happy with the results and have been able to supply in an adequate fashion the blood requirements of an isolated yet extremely active population with a sophisticated medical community.


Assuntos
Bancos de Sangue/organização & administração , Hospitais com 100 a 299 Leitos , Número de Leitos em Hospital , Departamentos Hospitalares/organização & administração , Hospitais Comunitários , Bancos de Sangue/economia , Doadores de Sangue , Colorado , Hospitais Comunitários/economia , Humanos
11.
J Med Entomol ; 30(1): 20-6, 1993 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-8433327

RESUMO

Sixteen healthy cats were fed a 6-wk-old laboratory mouse that had died of experimentally induced Yersinia pestis infection (strain NM77-538), to simulate oral exposure to plague. The cats were closely monitored after ingestion. Physical exams were performed and vital signs were recorded daily. Plague antibody titers and cultures of blood, throat, and oral cavity were performed daily. Complete blood counts and biochemistry panels were performed every 3 d. Complete necropsies were performed on any cats that died. Cats exhibited one of three responses following ingestion of one plague-infected mouse; they either died (6/16 or 38%), developed transient illness and recovered (7/16 or 44%) or showed no signs of illness (3/16 or 19%). A continual fever greater > 40 degrees C was associated with a poor prognosis. The highest antibody titers developed in the group that shed the plague bacillus over an extended period of time. Blood, throat, and oral cavity cultures were positive in 100% of the fatal cases. Throat cultures were positive in 75% of the exposed cats. In contrast to other carnivores, cats infected with Y. pestis exhibit bubo formation and pneumonic lesions similar to those seen in people with plague. Because of the potential transmission of Y. pestis from cats to people, development of a plague vaccine for cats may be warranted.


Assuntos
Doenças do Gato/etiologia , Peste/transmissão , Zoonoses , Animais , Anticorpos Antibacterianos/biossíntese , Doenças do Gato/imunologia , Gatos , Peste/etiologia , Peste/imunologia , Yersinia pestis/imunologia , Yersinia pestis/isolamento & purificação
12.
Mutat Res ; 148(1-2): 135-49, 1985.
Artigo em Inglês | MEDLINE | ID: mdl-3969078

RESUMO

We report that we are unable to repeat consistently the results published by Ansari et al. (1980) using antibodies to detect mutations in lactate dehydrogenase-C (LDH-C, previously called LDH-X) directly in sperm of mice exposed to the mutagen procarbazine. The approach made use of the interspecies differences in the antigenic sites between the LDH-C of the rat and mouse in sperm. The visualization of mutations in mouse LDH-C was based on the detection of alterations in antigenic sites of mouse LDH-C such that mouse sperm would bind the antibody that was specific for rat LDH-C (presumptive mutants); the antibody was termed specific when it immunofluorescently labeled rat sperm but not mouse sperm. The original work reported increases in the frequency of occurrence of mouse sperm that would bind rat-specific antibody from mice treated with procarbazine as compared control mice; a single absorbed antiserum was used throughout the experiments. In this study, we found that there is too much variation in the frequency of mouse sperm that react with rabbit antibodies to purified rat LDH-C for the system to be useful in mutagenesis studies. The fundamental criterion of antibody specificity was maintained as in the original work. The frequency of labeled mouse sperm depended on the absorption of the antibody on mouse proteins, indicating that the factors denoting a presumptive mutant were associated with the mouse proteins. In some experiments, the frequency of labeled mouse sperm was higher among sperm from procarbazine-treated mice than among sperm from control mice. This increase, however, was not consistently reproducible. After extensive absorption of the antibody on mouse proteins, no presumptive mutants were observed in sperm from treated and control animals; these antibodies continued to immunofluorescently label rat sperm. The absence of presumptive mutants with highly absorbed antibody suggests that natural variation between species may not be appropriate as markers for the detection of mutations without a thorough knowledge of the number of independent events at the DNA level required to produce a change in antigenic recognition.


Assuntos
L-Lactato Desidrogenase/imunologia , Mutação , Animais , Especificidade de Anticorpos , Reações Cruzadas , Isoenzimas , L-Lactato Desidrogenase/genética , L-Lactato Desidrogenase/isolamento & purificação , Masculino , Camundongos , Espermatozoides/enzimologia , Temperatura
13.
J Environ Radioact ; 138: 444-6, 2014 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-24725806

RESUMO

The decays of (214)Po into (210)Pb and of (212)Po into (208)Pb tagged by the previous decays from (214)Bi and (212)Bi have been studied inserting quartz vials inside the Counting Test Facility (CTF) at the underground laboratory in Gran Sasso (LNGS). We find that the mean lifetime of (214)Po is (236.00 ± 0.42(stat) ± 0.15(syst)) µs and that of (212)Po is (425.1 ± 0.9(stat) ± 1.2(syst)) ns. Our results are compatible with previous measurements, have a much better signal to background ratio, and reduce the overall uncertainties.


Assuntos
Radioisótopos de Chumbo/análise , Polônio/análise , Poluentes Radioativos/análise , Partículas alfa , Meia-Vida , Laboratórios , Monitoramento de Radiação
15.
Phys Rev Lett ; 101(9): 091302, 2008 Aug 29.
Artigo em Inglês | MEDLINE | ID: mdl-18851600

RESUMO

We report the direct measurement of the 7Be solar neutrino signal rate performed with the Borexino detector at the Laboratori Nazionali del Gran Sasso. The interaction rate of the 0.862 MeV 7Be neutrinos is 49+/-3stat+/-4syst counts/(day.100 ton). The hypothesis of no oscillation for 7Be solar neutrinos is inconsistent with our measurement at the 4sigma C.L. Our result is the first direct measurement of the survival probability for solar nu(e) in the transition region between matter-enhanced and vacuum-driven oscillations. The measurement improves the experimental determination of the flux of 7Be, pp, and CNO solar nu(e), and the limit on the effective neutrino magnetic moment using solar neutrinos.

16.
Appl Opt ; 26(2): 343-50, 1987 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-20454135

RESUMO

The design and performance of several dispersive spectrometers for reflection absorption infrared spectroscopy are presented. Sources of noise and their control are discussed in detail. Individual component selection for the spectrometers is discussed with particular attention paid to optimizing sensitivity for surface measurements. These efforts culminated in an ellipsometric spectrometer with a sensitivity of <0.01% absorption and capable of following transients with a temporal resolution of 10 ms.

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