RESUMO
A 23 year old man, expert in karate, complained of sudden movements of right hip during "circular kicks", followed by persistent pain. Arthrography showed synovial plication in joint at upper border femoral neck, with a tongue-like projection from upper recess extending to head/neck junction and provoking bone erosion visible on standard images. Recovery followed resection of the fold. This is probably the first case of this type to be published. The lesion recalls the internal synovial plica of knee but differs from "frenula capsulae" and does not appear to have been described by anatomists. As in the knee it is probably an embryonic relic.
Assuntos
Articulação do Quadril/diagnóstico por imagem , Osteólise/etiologia , Membrana Sinovial/diagnóstico por imagem , Adulto , Humanos , Masculino , Osteólise/diagnóstico por imagem , Radiografia , Membrana Sinovial/embriologiaRESUMO
Two new SH-CH3-containing drugs have been studied as penicillamine-like agents. Pyrithioxine--retrospectively compared to a D-penicillamine series--was associated with fewer side effect-related withdrawals (14 vs 39) but with more non-responses and withdrawals for relapse. A review of the literature shows that thiopronine and D-penicillamine have a similar "score" of side effects and good responses. More extensively-controlled trials are needed for a better assessment of these new drugs.
Assuntos
Aminoácidos Sulfúricos/uso terapêutico , Artrite Reumatoide/tratamento farmacológico , Penicilamina/uso terapêutico , Piridinas/uso terapêutico , Piritioxina/uso terapêutico , Tiopronina/uso terapêutico , Adulto , Idoso , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-IdadeAssuntos
Aminoácidos Sulfúricos/uso terapêutico , Artrite Reumatoide/tratamento farmacológico , Penicilamina/uso terapêutico , Piridinas/uso terapêutico , Piritioxina/uso terapêutico , Tiopronina/uso terapêutico , Humanos , Penicilamina/efeitos adversos , Piritioxina/efeitos adversos , Compostos de Sulfidrila/uso terapêuticoRESUMO
The authors present their own series of 70 rheumatoidpolyarthritis cases treated with pyrithioxine during one year or more except in the case of failure or intolerance. The following results were observed after one year: 54 percent showed positive results, 34 percent showed no results or dubious ones, and there was 13 percent of discontinuance because of intolerance. Modifications of the posology and methods of administering are proposed, and the role of pyrithioxine, as a basic treatment for rheumatoid polyarthritis, is discussed.
Assuntos
Artrite Reumatoide/tratamento farmacológico , Piridinas/uso terapêutico , Piritioxina/uso terapêutico , Adulto , Idoso , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Piritioxina/administração & dosagem , Piritioxina/efeitos adversosRESUMO
After presenting two personal observations, the authors underline the fact that the neurological manifestations of Behçet's disease are more frequent than they were supposed to be. Their symptoms are overly manifold but have in common constant abnormality in the cerebrospinal fluid when an attack occurs. The affection is a very serious one demanding an early and well established diagnosis only to be obtained thanks to a clinical examination. Corticosteroïd therapy (1 mg/kg per day) either alone or associated with immuno-suppressive therapy may check the attack. Preventing relapses implies a non-stop treatment. Immuno-suppressive therapy seems to be the most efficient one.
Assuntos
Síndrome de Behçet/complicações , Doenças do Sistema Nervoso Central/etiologia , Corticosteroides/uso terapêutico , Adulto , Síndrome de Behçet/diagnóstico , Síndrome de Behçet/tratamento farmacológico , Feminino , Humanos , Imunossupressores/uso terapêutico , MasculinoRESUMO
The authors report three observations of patients having suffered from arthralgias as an aftermath of intestinal by-pass for treatment of refractory obesity. They remind the main troubles cropping up after such surgical treatment and refer to the data already existing in the literature dealing with articular manifestations. They think this pathology is in keeping with arthritis already reported in inflammatory colitis and they suggest a similar pathogeny.