Detalhe da pesquisa
1.
Molecular Basis of Assembly and Activation of Complement Component C1 in Complex with Immunoglobulin G1 and Antigen.
Mol Cell
; 63(1): 135-45, 2016 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27320199
2.
Staphylococcal protein A inhibits complement activation by interfering with IgG hexamer formation.
Proc Natl Acad Sci U S A
; 118(7)2021 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33563762
3.
C1q binding to surface-bound IgG is stabilized by C1r2s2 proteases.
Proc Natl Acad Sci U S A
; 118(26)2021 06 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34155115
4.
Complement alone drives efficacy of a chimeric antigonococcal monoclonal antibody.
PLoS Biol
; 17(6): e3000323, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31216278
5.
Bypassing Phase Variation of Lipooligosaccharide (LOS): Using Heptose 1 Glycan Mutants To Establish Widespread Efficacy of Gonococcal Anti-LOS Monoclonal Antibody 2C7.
Infect Immun
; 88(2)2020 01 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31818965
6.
Unraveling the Macromolecular Pathways of IgG Oligomerization and Complement Activation on Antigenic Surfaces.
Nano Lett
; 19(7): 4787-4796, 2019 07 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31184907
7.
CD20 and CD37 antibodies synergize to activate complement by Fc-mediated clustering.
Haematologica
; 104(9): 1841-1852, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30792198
8.
A Novel Platform for the Potentiation of Therapeutic Antibodies Based on Antigen-Dependent Formation of IgG Hexamers at the Cell Surface.
PLoS Biol
; 14(1): e1002344, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26736041
9.
Monoclonal Antibodies against Epidermal Growth Factor Receptor Acquire an Ability To Kill Tumor Cells through Complement Activation by Mutations That Selectively Facilitate the Hexamerization of IgG on Opsonized Cells.
J Immunol
; 198(4): 1585-1594, 2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28062698
10.
Antibodies That Efficiently Form Hexamers upon Antigen Binding Can Induce Complement-Dependent Cytotoxicity under Complement-Limiting Conditions.
J Immunol
; 197(5): 1762-75, 2016 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27474078
11.
Type I CD20 Antibodies Recruit the B Cell Receptor for Complement-Dependent Lysis of Malignant B Cells.
J Immunol
; 197(12): 4829-4837, 2016 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27807190
12.
Hexamerization-enhanced CD20 antibody mediates complement-dependent cytotoxicity in serum genetically deficient in C9.
Clin Immunol
; 181: 24-28, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28578024
13.
A Complement-Optimized EGFR Antibody Improves Cytotoxic Functions of Polymorphonuclear Cells against Tumor Cells.
J Immunol
; 195(10): 5077-87, 2015 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26475927
14.
Ibrutinib interferes with the cell-mediated anti-tumor activities of therapeutic CD20 antibodies: implications for combination therapy.
Haematologica
; 100(1): 77-86, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25344523
15.
Complement in antibody-based tumor therapy.
Crit Rev Immunol
; 34(3): 199-214, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24941073
16.
Exhaustion of cytotoxic effector systems may limit monoclonal antibody-based immunotherapy in cancer patients.
J Immunol
; 188(7): 3532-41, 2012 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22368276
17.
Loss of CD20 and bound CD20 antibody from opsonized B cells occurs more rapidly because of trogocytosis mediated by Fc receptor-expressing effector cells than direct internalization by the B cells.
J Immunol
; 187(6): 3438-47, 2011 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21841127
18.
Fc receptor but not complement binding is important in antibody protection against HIV.
Nature
; 449(7158): 101-4, 2007 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-17805298
19.
Promoting Fc-Fc interactions between anti-capsular antibodies provides strong immune protection against Streptococcus pneumoniae.
Elife
; 122023 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36947116
20.
Penetration of antibody-opsonized cells by the membrane attack complex of complement promotes Ca(2+) influx and induces streamers.
Eur J Immunol
; 41(8): 2436-46, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21674476