Detalhe da pesquisa
1.
CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition.
Nature
; 604(7907): 749-756, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35444283
2.
Discovery of an Orally Bioavailable and Selective PKMYT1 Inhibitor, RP-6306.
J Med Chem
; 65(15): 10251-10284, 2022 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35880755
3.
The CIP2A-TOPBP1 axis safeguards chromosome stability and is a synthetic lethal target for BRCA-mutated cancer.
Nat Cancer
; 2(12): 1357-1371, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35121901
4.
Characterization of Functionally Associated miRNAs in Glioblastoma and their Engineering into Artificial Clusters for Gene Therapy.
J Vis Exp
; (152)2019 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31633695
5.
MicroRNAs in Brain Cancer: Look at the Forest, Not at the Tree.
J Exp Neurosci
; 13: 1179069519839693, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30956527
6.
Engineering, delivery, and biological validation of artificial microRNA clusters for gene therapy applications.
Nat Protoc
; 14(12): 3538-3553, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31748752
7.
The functional synergism of microRNA clustering provides therapeutically relevant epigenetic interference in glioblastoma.
Nat Commun
; 10(1): 442, 2019 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30683859
8.
Arming an Oncolytic Herpes Simplex Virus Type 1 with a Single-chain Fragment Variable Antibody against PD-1 for Experimental Glioblastoma Therapy.
Clin Cancer Res
; 25(1): 290-299, 2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30279232
9.
Development of a Function-Blocking Antibody Against Fibulin-3 as a Targeted Reagent for Glioblastoma.
Clin Cancer Res
; 24(4): 821-833, 2018 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29146721
10.
Correction: Arming an Oncolytic Herpes Simplex Virus Type 1 with a Single-chain Fragment Variable Antibody against PD-1 for Experimental Glioblastoma Therapy.
Clin Cancer Res
; 26(3): 758, 2020 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32014888