Detalhe da pesquisa
1.
In Vitro: Cytotoxicity, Apoptosis and Ameliorative Potential of Lawsonia inermis Extract in Human Lung, Colon and Liver Cancer Cell Line.
Cancer Invest
; 38(8-9): 476-485, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-32845783
2.
Evaluation of interconversion pharmacokinetics of 16α-hydroxycleroda-3,13(14)Z-dien-15,16-olide - a novel HMG-CoA reductase inhibitor and its acid metabolite using multi-compartmental pharmacokinetic model in mice.
Xenobiotica
; 49(4): 474-483, 2019 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-29565234
3.
Pharmacokinetics, Metabolism, and Partial Biodistribution of "Pincer Therapeutic" Nitazoxanide in Mice following Pulmonary Delivery of Inhalable Particles.
Mol Pharm
; 14(4): 1204-1211, 2017 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28263078
4.
Simultaneous quantitation of acetylsalicylic acid and clopidogrel along with their metabolites in human plasma using liquid chromatography tandem mass spectrometry.
Biomed Chromatogr
; 30(3): 466-73, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26230053
5.
Metabolic profiling of a novel antithrombotic compound, S002-333 and enantiomers: metabolic stability, species comparison and in vitro-in vivo extrapolation.
Biopharm Drug Dispos
; 37(4): 185-99, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26477787
6.
Dithiocarbamate-thiourea hybrids useful as vaginal microbicides also show reverse transcriptase inhibition: design, synthesis, docking and pharmacokinetic studies.
Bioorg Med Chem Lett
; 25(4): 881-6, 2015 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25592712
7.
Pharmacokinetics and tissue distribution study of novel potent antiplatelet agent S007-867 in mice using HPLC-MS/MS.
Xenobiotica
; 45(6): 530-7, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25837690
8.
Synthesis and evaluation of new 3-phenylcoumarin derivatives as potential antidepressant agents.
Bioorg Med Chem Lett
; 24(20): 4876-80, 2014 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25239852
9.
Design and synthesis of substituted morpholin/piperidin-1-yl-carbamodithioates as promising vaginal microbicides with spermicidal potential.
Bioorg Med Chem Lett
; 24(24): 5782-5786, 2014 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25453819
10.
Discovery, SAR and mechanistic studies of quinazolinone-based acetamide derivatives in experimental visceral leishmaniasis.
Eur J Med Chem
; 257: 115524, 2023 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37290183
11.
Antileishmanial assessment of isoxazole derivatives against L. donovani.
RSC Med Chem
; 11(9): 1053-1062, 2020 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33479698
12.
Anti-ageing and anti-Parkinsonian effects of natural flavonol, tambulin from Zanthoxyllum aramatum promotes longevity in Caenorhabditis elegans.
Exp Gerontol
; 120: 50-61, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30825547
13.
Liquid chromatography-tandem mass spectrometry based method development and validation of S016-1271 (LR8P), a novel cationic antimicrobial peptide for its application to pharmacokinetic studies.
J Pharm Biomed Anal
; 169: 116-126, 2019 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30851514
14.
In-vitro metabolism, CYP profiling and metabolite identification of E- and Z- guggulsterone, a potent hypolipidmic agent.
J Pharm Biomed Anal
; 160: 202-211, 2018 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30099292
15.
Shatavarin IV elicits lifespan extension and alleviates Parkinsonism in Caenorhabditis elegans.
Free Radic Res
; 51(11-12): 954-969, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29069955
16.
Bioflavonoid hesperetin overcome bicalutamide induced toxicity by co-delivery in novel SNEDDS formulations: Optimization, in vivo evaluation and uptake mechanism.
Mater Sci Eng C Mater Biol Appl
; 71: 954-964, 2017 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27987794
17.
Biological evaluation of novel curcumin-pyrazole-mannich derivative active against drug-resistant Mycobacterium tuberculosis.
Future Microbiol
; 12: 1349-1362, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29035081
18.
Assessment of in vitro metabolic stability, plasma protein binding, and pharmacokinetics of E- and Z-guggulsterone in rat.
Drug Test Anal
; 8(9): 966-75, 2016 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26608935
19.
Assessement of the pharmacokinetics, tissue distribution and excretion studies of a novel antiplatelet agent S007-867, following administration to rats.
Drug Test Anal
; 8(7): 723-9, 2016 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26147430
20.
Amphotericin-B entrapped lecithin/chitosan nanoparticles for prolonged ocular application.
Int J Biol Macromol
; 72: 1451-8, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25453292