Detalhe da pesquisa
1.
A novel human cellular model of CDA IV enables comprehensive analysis revealing the molecular basis of the disease phenotype.
Blood
; 141(25): 3039-3054, 2023 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37084386
2.
Association of DDX5/p68 protein with the upstream erythroid enhancer element (EHS1) of the gene encoding the KLF1 transcription factor.
J Biol Chem
; 299(12): 105489, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38000658
3.
Patients with hypercortisolemic Cushing disease possess a distinct class of hematopoietic progenitor cells leading to erythrocytosis.
Haematologica
; 108(4): 1053-1067, 2023 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35861015
4.
Neomorphic effects of the neonatal anemia (Nan-Eklf) mutation contribute to deficits throughout development.
Development
; 144(3): 430-440, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28143845
5.
KLF1/EKLF expression in acute leukemia is correlated with chromosomal abnormalities.
Blood Cells Mol Dis
; 83: 102434, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32311573
6.
Genetic disarray follows mutant KLF1-E325K expression in a congenital dyserythropoietic anemia patient.
Haematologica
; 104(12): 2372-2380, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30872368
7.
Promiscuous DNA-binding of a mutant zinc finger protein corrupts the transcriptome and diminishes cell viability.
Nucleic Acids Res
; 45(3): 1130-1143, 2017 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28180284
8.
EKLF/KLF1-regulated cell cycle exit is essential for erythroblast enucleation.
Blood
; 128(12): 1631-41, 2016 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27480112
9.
Krüppeling erythropoiesis: an unexpected broad spectrum of human red blood cell disorders due to KLF1 variants.
Blood
; 127(15): 1856-62, 2016 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26903544
10.
A Systems Approach Identifies Essential FOXO3 Functions at Key Steps of Terminal Erythropoiesis.
PLoS Genet
; 11(10): e1005526, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26452208
11.
Orchestration of late events in erythropoiesis by KLF1/EKLF.
Curr Opin Hematol
; 24(3): 183-190, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28157724
12.
Extrinsic and intrinsic control by EKLF (KLF1) within a specialized erythroid niche.
Development
; 141(11): 2245-54, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24866116
13.
A master erythroid regulator gets its own GPS.
Blood
; 135(25): 2209-2210, 2020 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32556132
14.
Transcription factor EKLF (KLF1) recruitment of the histone chaperone HIRA is essential for ß-globin gene expression.
Proc Natl Acad Sci U S A
; 111(37): 13337-42, 2014 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-25197097
15.
Transcriptional activity of erythroid Kruppel-like factor (EKLF/KLF1) modulated by PIAS3 (protein inhibitor of activated STAT3).
J Biol Chem
; 290(15): 9929-40, 2015 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25713074
16.
KLF1: when less is more.
Blood
; 124(5): 672-3, 2014 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-25082863
17.
Structural and functional characterization of an atypical activation domain in erythroid Kruppel-like factor (EKLF).
Proc Natl Acad Sci U S A
; 108(26): 10484-9, 2011 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21670263
18.
Functional interactions between erythroid Krüppel-like factor (EKLF/KLF1) and protein phosphatase PPM1B/PP2Cß.
J Biol Chem
; 287(19): 15193-204, 2012 May 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-22393050
19.
T-cell acute leukemia 1 (TAL1) regulation of erythropoietin receptor and association with excessive erythrocytosis.
J Biol Chem
; 287(44): 36720-31, 2012 Oct 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-22982397
20.
Erythroid transcription factor EKLF/KLF1 mutation causing congenital dyserythropoietic anemia type IV in a patient of Taiwanese origin: review of all reported cases and development of a clinical diagnostic paradigm.
Blood Cells Mol Dis
; 51(2): 71-5, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23522491