Detalhe da pesquisa
1.
In vitro production of infectious Plasmodium falciparum sporozoites.
Nature
; 612(7940): 534-539, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36477528
2.
Two chemoattenuated PfSPZ malaria vaccines induce sterile hepatic immunity.
Nature
; 595(7866): 289-294, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34194041
3.
Knockout of Anopheles stephensi immune gene LRIM1 by CRISPR-Cas9 reveals its unexpected role in reproduction and vector competence.
PLoS Pathog
; 17(11): e1009770, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34784388
4.
Sterile protection against human malaria by chemoattenuated PfSPZ vaccine.
Nature
; 542(7642): 445-449, 2017 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28199305
5.
Diagnostic performance and comparison of ultrasensitive and conventional rapid diagnostic test, thick blood smear and quantitative PCR for detection of low-density Plasmodium falciparum infections during a controlled human malaria infection study in Equatorial Guinea.
Malar J
; 21(1): 99, 2022 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35331251
6.
Multidose Priming and Delayed Boosting Improve Plasmodium falciparum Sporozoite Vaccine Efficacy Against Heterologous P. falciparum Controlled Human Malaria Infection.
Clin Infect Dis
; 73(7): e2424-e2435, 2021 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32920641
7.
Transient knockdown of Anopheles stephensi LRIM1 using RNAi increases Plasmodium falciparum sporozoite salivary gland infections.
Malar J
; 20(1): 284, 2021 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34174879
8.
Incidence of Plasmodium falciparum malaria infection in 6-month to 45-year-olds on selected areas of Bioko Island, Equatorial Guinea.
Malar J
; 20(1): 322, 2021 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34284778
9.
Serologic Markers of Previous Malaria Exposure and Functional Antibodies Inhibiting Parasite Growth Are Associated With Parasite Kinetics Following a Plasmodium falciparum Controlled Human Infection.
Clin Infect Dis
; 70(12): 2544-2552, 2020 06 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31402382
10.
Safety, Tolerability, and Immunogenicity of Plasmodium falciparum Sporozoite Vaccine Administered by Direct Venous Inoculation to Infants and Young Children: Findings From an Age De-escalation, Dose-Escalation, Double-blind, Randomized Controlled Study in Western Kenya.
Clin Infect Dis
; 71(4): 1063-1071, 2020 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31555824
11.
Increase of Dose Associated With Decrease in Protection Against Controlled Human Malaria Infection by PfSPZ Vaccine in Tanzanian Adults.
Clin Infect Dis
; 71(11): 2849-2857, 2020 12 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-31782768
12.
Attenuated PfSPZ Vaccine induces strain-transcending T cells and durable protection against heterologous controlled human malaria infection.
Proc Natl Acad Sci U S A
; 114(10): 2711-2716, 2017 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28223498
13.
Is Saglin a mosquito salivary gland receptor for Plasmodium falciparum?
Malar J
; 18(1): 2, 2019 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30602380
14.
Impact of malaria preexposure on antiparasite cellular and humoral immune responses after controlled human malaria infection.
Infect Immun
; 83(5): 2185-96, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25776749
15.
Robust, reproducible, industrialized, standard membrane feeding assay for assessing the transmission blocking activity of vaccines and drugs against Plasmodium falciparum.
Malar J
; 14: 150, 2015 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25890243
16.
Lessons learnt from the first controlled human malaria infection study conducted in Nairobi, Kenya.
Malar J
; 14: 182, 2015 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25927522
17.
Direct venous inoculation of Plasmodium falciparum sporozoites for controlled human malaria infection: a dose-finding trial in two centres.
Malar J
; 14: 117, 2015 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25889522
18.
Controlled human malaria infection by intramuscular and direct venous inoculation of cryopreserved Plasmodium falciparum sporozoites in malaria-naïve volunteers: effect of injection volume and dose on infectivity rates.
Malar J
; 14: 306, 2015 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26245196
19.
A paradigm for Africa-centric vaccine development in Equatorial Guinea.
Trends Parasitol
; 40(5): 362-366, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38582683
20.
Safety and protective efficacy of PfSPZ Vaccine administered to HIV-negative and -positive Tanzanian adults.
J Clin Invest
; 134(6)2024 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38194272