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1.
J Hand Surg Eur Vol ; 41(4): 380-5, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-26261228

RESUMO

UNLABELLED: The purpose of this study was to assess the lengths of the index and middle finger proximal interphalangeal joint ligaments and determine the relative changes in the collateral and accessory collateral ligament lengths at 0°, 45° and 90° flexion. We generated three-dimensional scans of 16 finger (eight index and eight middle) proximal interphalangeal joints to assess relative changes in ligament length. Significant changes were found between 45°-90° and 0°-90° for the ulnar collateral ligament of the index finger and both collateral ligaments of the middle finger between 45°-90° and 0°-90°. No significant changes in length were found for the radial collateral ligament of the index finger or the accessory collateral ligaments of the index and middle fingers. Overall, it was found that the collateral ligament length changed significantly, but there was no significant change in the accessory collateral ligaments. TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic IV.


Assuntos
Ligamentos Colaterais/fisiologia , Articulações dos Dedos/fisiologia , Processamento de Imagem Assistida por Computador , Imageamento Tridimensional , Lasers , Idoso , Idoso de 80 Anos ou mais , Cadáver , Feminino , Humanos , Masculino
2.
Bone Joint J ; 95-B(8): 1094-100, 2013 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-23908426

RESUMO

In Canada, Dupuytren's contracture is managed with partial fasciectomy or percutaneous needle aponeurotomy (PNA). Injectable collagenase will soon be available. The optimal management of Dupuytren's contracture is controversial and trade-offs exist between the different methods. Using a cost-utility analysis approach, our aim was to identify the most cost-effective form of treatment for managing Dupuytren's contracture it and the threshold at which collagenase is cost-effective. We developed an expected-value decision analysis model for Dupuytren's contracture affecting a single finger, comparing the cost-effectiveness of fasciectomy, aponeurotomy and collagenase from a societal perspective. Cost-effectiveness, one-way sensitivity and variability analyses were performed using standard thresholds for cost effective treatment ($50 000 to $100 000/QALY gained). Percutaneous needle aponeurotomy was the preferred strategy for managing contractures affecting a single finger. The cost-effectiveness of primary aponeurotomy improved when repeated to treat recurrence. Fasciectomy was not cost-effective. Collagenase was cost-effective relative to and preferred over aponeurotomy at $875 and $470 per course of treatment, respectively. In summary, our model supports the trend towards non-surgical interventions for managing Dupuytren's contracture affecting a single finger. Injectable collagenase will only be feasible in our publicly funded healthcare system if it costs significantly less than current United States pricing.


Assuntos
Contratura de Dupuytren/economia , Contratura de Dupuytren/terapia , Custos de Cuidados de Saúde/estatística & dados numéricos , Modelos Econométricos , Algoritmos , Canadá , Colagenases/administração & dosagem , Colagenases/economia , Colagenases/uso terapêutico , Análise Custo-Benefício , Técnicas de Apoio para a Decisão , Custos de Medicamentos/estatística & dados numéricos , Fasciotomia , Humanos , Injeções Intralesionais , Complicações Pós-Operatórias/economia , Anos de Vida Ajustados por Qualidade de Vida
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