Detalhe da pesquisa
1.
Structure-activity study of oncocin: On-resin guanidinylation and incorporation of homoarginine, 4-hydroxyproline or 4,4-difluoroproline residues.
Bioorg Chem
; 141: 106876, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37797458
2.
Selected strategies to fight pathogenic bacteria.
J Enzyme Inhib Med Chem
; 38(1): 2155816, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36629427
3.
Evaluation of 1H-Triazole-1-[N,N'-Bis(tert-butoxycarbonyl)]carboxamidine in Solution-Phase and On-Resin Guanidinylation.
J Org Chem
; 86(21): 14371-14380, 2021 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34661410
4.
Peptide/ß-Peptoid Hybrids with Ultrashort PEG-Like Moieties: Effects on Hydrophobicity, Antibacterial Activity and Hemolytic Properties.
Int J Mol Sci
; 22(13)2021 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34208826
5.
Discovery of Novel Non-Steroidal Cytochrome P450 17A1 Inhibitors as Potential Prostate Cancer Agents.
Int J Mol Sci
; 21(14)2020 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32660148
6.
Silver carbene complexes: An emerging class of anticancer agents.
Drug Dev Res
; 80(2): 188-199, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30387164
7.
Peptide/Peptoid Hybrid Oligomers: The Influence of Hydrophobicity and Relative Side-Chain Length on Antibacterial Activity and Cell Selectivity.
Molecules
; 24(24)2019 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31817108
8.
Polymyxins with Potent Antibacterial Activity against Colistin-Resistant Pathogens: Fine-Tuning Hydrophobicity with Unnatural Amino Acids.
J Med Chem
; 67(2): 1370-1383, 2024 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38169430
9.
Studies of antibacterial activity (in vitro and in vivo) and mode of action for des-acyl tridecaptins (DATs).
Eur J Med Chem
; 265: 116097, 2024 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38157595
10.
[18F]FDG and [18F]FLT positron emission tomography imaging following treatment with belinostat in human ovary cancer xenografts in mice.
BMC Cancer
; 13: 168, 2013 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23548101
11.
Non-steroidal CYP17A1 Inhibitors: Discovery and Assessment.
J Med Chem
; 66(10): 6542-6566, 2023 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37191389
12.
Antimicrobial Peptides Incorporating Halogenated Marine-Derived Amino Acid Substituents.
ACS Med Chem Lett
; 14(6): 802-809, 2023 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37312845
13.
Exploring the Potential of Sulfur Moieties in Compounds Inhibiting Steroidogenesis.
Biomolecules
; 13(9)2023 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37759751
14.
Inhibitors of human histone deacetylase with potent activity against the African trypanosome Trypanosoma brucei.
Bioorg Med Chem Lett
; 22(5): 1886-90, 2012 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22326398
15.
Prediction of drug efficacy for cancer treatment based on comparative analysis of chemosensitivity and gene expression data.
Bioorg Med Chem
; 20(1): 167-76, 2012 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22154557
16.
Synthesis and Structure-Activity Relationships of Novel Non-Steroidal CYP17A1 Inhibitors as Potential Prostate Cancer Agents.
Biomolecules
; 12(2)2022 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35204665
17.
Imitation of ß-lactam binding enables broad-spectrum metallo-ß-lactamase inhibitors.
Nat Chem
; 14(1): 15-24, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34903857
18.
Structural Basis of Metallo-ß-lactamase Inhibition by N-Sulfamoylpyrrole-2-carboxylates.
ACS Infect Dis
; 7(6): 1809-1817, 2021 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34003651
19.
Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase.
BMC Cancer
; 10: 677, 2010 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-21144000
20.
Alternating Cationic-Hydrophobic Peptide/Peptoid Hybrids: Influence of Hydrophobicity on Antibacterial Activity and Cell Selectivity.
ChemMedChem
; 15(24): 2544-2561, 2020 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33029927