Detalhe da pesquisa
1.
5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology.
Cell
; 172(4): 719-730.e14, 2018 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29398112
2.
Venom-inspired somatostatin receptor 4 (SSTR4) agonists as new drug leads for peripheral pain conditions.
bioRxiv
; 2024 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38746149
3.
Ligand selectivity hotspots in serotonin GPCRs.
Trends Pharmacol Sci
; 44(12): 978-990, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37914598
4.
(S)-2-Mercaptohistidine: A First Selective Orthosteric GluK3 Antagonist.
ACS Chem Neurosci
; 13(10): 1580-1587, 2022 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35475632
5.
Somatostatin venom analogs evolved by fish-hunting cone snails: From prey capture behavior to identifying drug leads.
Sci Adv
; 8(12): eabk1410, 2022 03 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35319982
6.
Curses or Cures: A Review of the Numerous Benefits Versus the Biosecurity Concerns of Conotoxin Research.
Biomedicines
; 8(8)2020 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32708023
7.
Identification and Structure-Activity Relationship Study of Imidazo[1,2-a]pyridine-3-amines as First Selective Inhibitors of Excitatory Amino Acid Transporter Subtype 3 (EAAT3).
ACS Chem Neurosci
; 10(10): 4414-4429, 2019 10 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31573179
8.
Design and Synthesis of 2,3- trans-Proline Analogues as Ligands for Ionotropic Glutamate Receptors and Excitatory Amino Acid Transporters.
ACS Chem Neurosci
; 10(6): 2989-3007, 2019 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31124660
9.
The importance of the excitatory amino acid transporter 3 (EAAT3).
Neurochem Int
; 98: 4-18, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27233497
10.
ß-Sulfonamido Functionalized Aspartate Analogues as Excitatory Amino Acid Transporter Inhibitors: Distinct Subtype Selectivity Profiles Arising from Subtle Structural Differences.
J Med Chem
; 59(19): 8771-8786, 2016 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-27636002
11.
Identification of a New Class of Selective Excitatory Amino Acid Transporter Subtype 1 (EAAT1) Inhibitors Followed by a Structure-Activity Relationship Study.
J Med Chem
; 59(19): 8757-8770, 2016 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-27626828
12.
New 4-Functionalized Glutamate Analogues Are Selective Agonists at Metabotropic Glutamate Receptor Subtype 2 or Selective Agonists at Metabotropic Glutamate Receptor Group III.
J Med Chem
; 59(3): 914-24, 2016 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26814576
13.
New Insight into the Structure-Activity Relationships of the Selective Excitatory Amino Acid Transporter Subtypeâ 1 (EAAT1) Inhibitors UCPH-101 and UCPH-102.
ChemMedChem
; 11(4): 382-402, 2016 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26757239
14.
Bioavailability Studies and inâ vitro Profiling of the Selective Excitatory Amino Acid Transporter Subtypeâ 1 (EAAT1) Inhibitor UCPH-102.
ChemMedChem
; 11(4): 403-19, 2016 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26797816
15.
Excitatory amino acid transporters: recent insights into molecular mechanisms, novel modes of modulation and new therapeutic possibilities.
Curr Opin Pharmacol
; 20: 116-23, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25466154