Detalhe da pesquisa
1.
Capturing the Binuclear Copper State of Peptidylglycine Monooxygenase Using a Peptidyl-Homocysteine Lure.
J Am Chem Soc
; 146(8): 5074-5080, 2024 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38363651
2.
Peptide Selenocysteine Substitutions Reveal Direct Substrate-Enzyme Interactions at Auxiliary Clusters in Radical S-Adenosyl-l-methionine Maturases.
J Am Chem Soc
; 145(18): 10167-10177, 2023 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37104670
3.
Pre-Steady-State Reactivity of Peptidylglycine Monooxygenase Implicates Ascorbate in Substrate Triggering of the Active Conformer.
Biochemistry
; 61(8): 665-677, 2022 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35380039
4.
The copper chaperone CCS facilitates copper binding to MEK1/2 to promote kinase activation.
J Biol Chem
; 297(6): 101314, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34715128
5.
The binuclear cluster of [FeFe] hydrogenase is formed with sulfur donated by cysteine of an [Fe(Cys)(CO)2(CN)] organometallic precursor.
Proc Natl Acad Sci U S A
; 116(42): 20850-20855, 2019 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31570604
6.
Ripping and stitching with copper.
Nat Chem Biol
; 20(4): 404-405, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38514883
7.
Catalytic M Center of Copper Monooxygenases Probed by Rational Design. Effects of Selenomethionine and Histidine Substitution on Structure and Reactivity.
Biochemistry
; 58(44): 4436-4446, 2019 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31626532
8.
Rational Design of a Histidine-Methionine Site Modeling the M-Center of Copper Monooxygenases in a Small Metallochaperone Scaffold.
Biochemistry
; 58(28): 3097-3108, 2019 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31243953
9.
Incorporation of Ni2+, Co2+, and Selenocysteine into the Auxiliary Fe-S Cluster of the Radical SAM Enzyme HydG.
Inorg Chem
; 58(19): 12601-12608, 2019 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31539235
10.
pH-Induced Binding of the Axial Ligand in an Engineered CuA Site Favors the πu State.
Inorg Chem
; 58(23): 15687-15691, 2019 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31710470
11.
Design of a single protein that spans the entire 2-V range of physiological redox potentials.
Proc Natl Acad Sci U S A
; 113(2): 262-7, 2016 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26631748
12.
Copper-zinc superoxide dismutase is activated through a sulfenic acid intermediate at a copper ion entry site.
J Biol Chem
; 292(29): 12025-12040, 2017 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28533431
13.
Tracking metal ions through a Cu/Ag efflux pump assigns the functional roles of the periplasmic proteins.
Proc Natl Acad Sci U S A
; 111(43): 15373-8, 2014 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25313055
14.
Substrate-Induced Carbon Monoxide Reactivity Suggests Multiple Enzyme Conformations at the Catalytic Copper M-Center of Peptidylglycine Monooxygenase.
Biochemistry
; 55(48): 6652-6661, 2016 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27933800
15.
Stopped-Flow Studies of the Reduction of the Copper Centers Suggest a Bifurcated Electron Transfer Pathway in Peptidylglycine Monooxygenase.
Biochemistry
; 55(13): 2008-21, 2016 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26982589
16.
Multicopper manganese oxidase accessory proteins bind Cu and heme.
Biochim Biophys Acta
; 1854(12): 1853-1859, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26327317
17.
Kß Valence to Core X-ray Emission Studies of Cu(I) Binding Proteins with Mixed Methionine - Histidine Coordination. Relevance to the Reactivity of the M- and H-sites of Peptidylglycine Monooxygenase.
Inorg Chem
; 55(7): 3431-9, 2016 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26965786
18.
Binuclear Cu(A) Formation in Biosynthetic Models of Cu(A) in Azurin Proceeds via a Novel Cu(Cys)2His Mononuclear Copper Intermediate.
Biochemistry
; 54(39): 6071-81, 2015 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26352296
19.
Alternative ground states enable pathway switching in biological electron transfer.
Proc Natl Acad Sci U S A
; 109(43): 17348-53, 2012 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23054836
20.
Binding of copper and silver to single-site variants of peptidylglycine monooxygenase reveals the structure and chemistry of the individual metal centers.
Biochemistry
; 53(6): 1069-80, 2014 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24471980