Detalhe da pesquisa
1.
Prognostic factors for response and overall survival in 282 patients with higher-risk myelodysplastic syndromes treated with azacitidine.
Blood
; 117(2): 403-11, 2011 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-20940414
2.
Efficacy and safety of lenalidomide in intermediate-2 or high-risk myelodysplastic syndromes with 5q deletion: results of a phase 2 study.
Blood
; 113(17): 3947-52, 2009 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-18987358
3.
Cytotoxic effects of the trifunctional bispecific antibody FBTA05 in ex-vivo cells of chronic lymphocytic leukaemia depend on immune-mediated mechanism.
Anticancer Drugs
; 22(6): 519-30, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21637160
4.
Erratum to: Flt3 receptor inhibition reduces constitutive NFκB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia.
Apoptosis
; 20(12): 1666-7, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26400497
5.
Flt3 receptor inhibition reduces constitutive NFkappaB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia.
Apoptosis
; 13(9): 1148-61, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18670883
6.
The tyrosine kinase inhibitor AMN107 (Nilotinib) exhibits off-target effects in lymphoblastic cell lines.
Leuk Lymphoma
; 48(7): 1379-88, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17613767
7.
Valproic acid stimulates proliferation and self-renewal of hematopoietic stem cells.
Cancer Res
; 65(7): 2537-41, 2005 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15805245
8.
The integrity of the charged pocket in the BTB/POZ domain is essential for the phenotype induced by the leukemia-associated t(11;17) fusion protein PLZF/RARalpha.
Cancer Res
; 65(14): 6080-8, 2005 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16024608
9.
The molecular biology of TRAIL-mediated signaling and its potential therapeutic exploitation in hematopoietic malignancies.
Curr Med Chem
; 13(18): 2091-100, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16918339
10.
Novel agents aiming at specific molecular targets increase chemosensitivity and overcome chemoresistance in hematopoietic malignancies.
Curr Pharm Des
; 12(1): 111-28, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16454729
11.
Prostate-apoptosis-response-gene-4 increases sensitivity to TRAIL-induced apoptosis.
Leuk Res
; 30(5): 597-605, 2006 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-16513168
12.
Daxx overexpression in T-lymphoblastic Jurkat cells enhances caspase-dependent death receptor- and drug-induced apoptosis in distinct ways.
Cell Signal
; 17(5): 581-95, 2005 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15683733
13.
In lymphatic cells par-4 sensitizes to apoptosis by down-regulating bcl-2 and promoting disruption of mitochondrial membrane potential and caspase activation.
Cancer Res
; 62(6): 1768-75, 2002 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-11912153
14.
AML-associated translocation products block vitamin D(3)-induced differentiation by sequestering the vitamin D(3) receptor.
Cancer Res
; 62(23): 7050-8, 2002 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12460926
15.
Prostate apoptosis response gene-4 (par-4) abrogates the survival function of p185(BCR-ABL) in hematopoietic cells.
Exp Hematol
; 32(7): 649-56, 2004 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15246161
16.
In bcr-abl-positive myeloid cells resistant to conventional chemotherapeutic agents, expression of Par-4 increases sensitivity to imatinib (STI571) and histone deacetylase-inhibitors.
Biochem Pharmacol
; 68(1): 85-93, 2004 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15183120
17.
Synergistic effects of chemotherapeutic drugs in lymphoma cells are associated with down-regulation of inhibitor of apoptosis proteins (IAPs), prostate-apoptosis-response-gene 4 (Par-4), death-associated protein (Daxx) and with enforced caspase activation.
Biochem Pharmacol
; 66(5): 711-24, 2003 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12948851
18.
In malignant myeloid cells expression of Daxx downregulates expression of p53 and of the inhibitors of apoptosis proteins.
Hematol J
; 5(6): 513-8, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-15570294
19.
Cytotoxic activity of T- and NK-cell lymphoma cells is not dependent on a mature cytotoxic phenotype.
Leuk Lymphoma
; 43(12): 2363-8, 2002 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-12613525
20.
Expression and function of prostate-apoptosis-response-gene-4 in lymphatic cells.
Leuk Lymphoma
; 43(9): 1737-41, 2002 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-12685825