Detalhe da pesquisa
1.
Atogepant for the preventive treatment of chronic migraine (PROGRESS): a randomised, double-blind, placebo-controlled, phase 3 trial.
Lancet
; 402(10404): 775-785, 2023 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37516125
2.
Linaclotide Reduced Response Time for Irritable Bowel Syndrome With Constipation Symptoms: Analysis of 4 Randomized Controlled Trials.
Am J Gastroenterol
; 118(5): 872-879, 2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36227782
3.
Phase Ib, open-label, fixed-sequence, drug-drug interaction, safety, and tolerability study between atogepant and ubrogepant in participants with a history of migraine.
Headache
; 63(3): 322-332, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36602199
4.
Safety and Efficacy of Eluxadoline in Patients with Irritable Bowel Syndrome-Diarrhea With or Without Bile Acid Diarrhea: Open-Label Study.
Dig Dis Sci
; 67(8): 3911-3921, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35122592
5.
Efficacy of Linaclotide in Reducing Abdominal Symptoms of Bloating, Discomfort, and Pain: A Phase 3B Trial Using a Novel Abdominal Scoring System.
Am J Gastroenterol
; 116(9): 1929-1937, 2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34465695
6.
Randomized Trial of 2 Delayed-Release Formulations of Linaclotide in Patients With Irritable Bowel Syndrome With Constipation.
Am J Gastroenterol
; 116(2): 354-361, 2021 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33065589
7.
Pharmacokinetics and safety of ubrogepant when coadministered with calcitonin gene-related peptide-targeted monoclonal antibody migraine preventives in participants with migraine: A randomized phase 1b drug-drug interaction study.
Headache
; 61(4): 642-652, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33818780
8.
Intestinal Guanylate Cyclase-C mRNA Expression in Duodenum and Colon of Children.
J Pediatr Gastroenterol Nutr
; 73(6): 703-709, 2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34508047
9.
Evaluation of the Pharmacokinetic Interaction of Ubrogepant Coadministered With Sumatriptan and of the Safety of Ubrogepant With Triptans.
Headache
; 60(7): 1340-1350, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32573795
10.
Pharmacokinetics and Safety of Vilazodone in Hepatic Impairment.
Am J Ther
; 22(4): 269-77, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25474324
11.
Pharmacokinetics of Ubrogepant in Healthy Japanese and White Adults.
Clin Pharmacol Drug Dev
; 2024 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38261231
12.
Pharmacokinetics and Safety of Atogepant Co-administered with Quinidine Gluconate in Healthy Participants: A Phase 1, Open-Label, Drug-Drug Interaction Study.
Clin Pharmacol Drug Dev
; 2024 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38702918
13.
Ubrogepant: Mechanism of action, clinical and translational science.
Clin Transl Sci
; 17(1): e13675, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38266060
14.
Atogepant: Mechanism of action, clinical and translational science.
Clin Transl Sci
; 17(1): e13707, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38266063
15.
Vilazodone lacks proarrhythmogenic potential in healthy participants: a thorough ECG study.
Int J Clin Pharmacol Ther
; 51(6): 456-65, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23611569
16.
Single-dose Pharmacokinetics of Eluxadoline in Healthy Participants With Normal Renal Function and Participants With Renal Impairment.
Clin Pharmacol Drug Dev
; 12(2): 132-140, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36504331
17.
Pharmacokinetics and Safety of Coadministered Atogepant and Topiramate in Healthy Participants: A Phase 1, Open-Label, Drug-Drug Interaction Study.
Clin Pharmacol Drug Dev
; 12(10): 1013-1021, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37210713
18.
Effects of CYP3A4 inhibition/induction and OATP inhibition on the pharmacokinetics of atogepant in healthy adults.
Pain Manag
; 2023 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37650778
19.
Evaluation of the pharmacokinetic interactions and safety of atogepant coadministered with esomeprazole.
Pain Manag
; 13(6): 351-361, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-37424270
20.
Randomised clinical trial: effects of MD-7246 on irritable bowel syndrome with diarrhoea.
Aliment Pharmacol Ther
; 57(2): 192-204, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36324245