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1.
Case Rep Pediatr ; 2018: 2750275, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29850344

RESUMO

Bartonella henselae is a Gram-negative bacterium and the causative agent of cat scratch disease (CSD). Atypical presentations of B. henselae that involve the musculoskeletal, hepatosplenic, cardiac, or neurologic systems are rare. In this case report, we describe a case of B. henselae osteomyelitis involving bilateral iliac bones complicated by hepatic lesions in a 12-year-old immunocompetent female patient. Although B. henselae is a rare cause of osteomyelitis, it should be considered when patients who present with fever, pain, and lymphadenopathy do not respond to routine osteomyelitis therapy.

2.
Clin Pediatr (Phila) ; 55(7): 673-6, 2016 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-26294760

RESUMO

We present the case of a young boy who was born to a human immunodeficiency virus (HIV)-positive mother and originally found to be uninfected. Evidence-based guidelines were followed regarding the mother's prenatal and infant's postnatal care, including the avoidance of breast milk. HIV DNA polymerase chain reaction qualitative tests were obtained at birth, 6 weeks and 4 months, and were all negative. He also received 6 weeks of prophylactic zidovudine. Despite these measures, his health began to decline at 17 months of age and antibody and serology tests performed at this time confirmed HIV infection. Guidelines no longer recommend routine antibody testing at 18 months of age to confirm the absence of infection in exposed infants with a record of negative virology in the first year of life. Based on this case and others we propose that this test be added back to the national guidelines for the early detection and prompt treatment of HIV infection in infants born to HIV-positive mothers.


Assuntos
Ensaio de Imunoadsorção Enzimática , Infecções por HIV/sangue , Infecções por HIV/diagnóstico , Transmissão Vertical de Doenças Infecciosas , Complicações Infecciosas na Gravidez/sangue , Fármacos Anti-HIV/administração & dosagem , Feminino , Citometria de Fluxo , Humanos , Lactente , Masculino , Reação em Cadeia da Polimerase , Gravidez , Zidovudina/administração & dosagem
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