Detalhe da pesquisa
1.
HDAC6 inhibition restores TDP-43 pathology and axonal transport defects in human motor neurons with TARDBP mutations.
EMBO J
; 40(7): e106177, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33694180
2.
Breast cancer cells rely on environmental pyruvate to shape the metastatic niche.
Nature
; 568(7750): 117-121, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30814728
3.
Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity.
Nature
; 566(7744): 403-406, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30728499
4.
Automated Generation of hiPSC-Derived Hepatic Progeny by Cost-Efficient Compounds.
Stem Cells
; 41(11): 1076-1088, 2023 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37616601
5.
A Novel UPLC-MS Metabolomic Analysis-Based Strategy to Monitor the Course and Extent of iPSC Differentiation to Hepatocytes.
J Proteome Res
; 21(3): 702-712, 2022 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34982937
6.
Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis.
EMBO J
; 35(9): 924-41, 2016 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26856890
7.
Human stem cell-derived monocytes and microglia-like cells reveal impaired amyloid plaque clearance upon heterozygous or homozygous loss of TREM2.
Alzheimers Dement
; 15(3): 453-464, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30442540
8.
Dual loss of succinate dehydrogenase (SDH) and complex I activity is necessary to recapitulate the metabolic phenotype of SDH mutant tumors.
Metab Eng
; 43(Pt B): 187-197, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27847310
9.
Stem cell-derived hepatocytes: A novel model for hepatitis E virus replication.
J Hepatol
; 64(3): 565-73, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26626494
10.
Osmolar Modulation Drives Reversible Cell Cycle Exit and Human Pluripotent Cell Differentiation via NF-κÐ and WNT Signaling.
Adv Sci (Weinh)
; 11(7): e2307554, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38037844
11.
Inhibition of the proline metabolism rate-limiting enzyme P5CS allows proliferation of glutamine-restricted cancer cells.
Nat Metab
; 5(12): 2131-2147, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37957387
12.
Metabolically Improved Stem Cell Derived Hepatocyte-Like Cells Support HBV Life Cycle and Are a Promising Tool for HBV Studies and Antiviral Drug Screenings.
Biomedicines
; 10(2)2022 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35203482
13.
The Black Box of Technological Outcome Measures: An Example in Duchenne Muscular Dystrophy.
J Neuromuscul Dis
; 9(4): 555-569, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35723109
14.
Metabolic Fuel for Epigenetic: Nuclear Production Meets Local Consumption.
Front Genet
; 12: 768996, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34804127
15.
Systematic transcriptome-based comparison of cellular adaptive stress response activation networks in hepatic stem cell-derived progeny and primary human hepatocytes.
Toxicol In Vitro
; 73: 105107, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-33545341
16.
A fully defined matrix to support a pluripotent stem cell derived multi-cell-liver steatohepatitis and fibrosis model.
Biomaterials
; 276: 121006, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34304139
17.
PU.1 drives specification of pluripotent stem cell-derived endothelial cells to LSEC-like cells.
Cell Death Dis
; 12(1): 84, 2021 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33446637
18.
A unique subset of glycolytic tumour-propagating cells drives squamous cell carcinoma.
Nat Metab
; 3(2): 182-195, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33619381
19.
Nuclear metabolism and the regulation of the epigenome.
Nat Metab
; 2(11): 1190-1203, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33046909
20.
Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines.
Nat Commun
; 11(1): 1393, 2020 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32170132