Assuntos
Doenças Cardiovasculares/diagnóstico , Ablação por Cateter/normas , Competência Clínica/normas , Cardioversão Elétrica/normas , Técnicas Eletrofisiológicas Cardíacas/normas , American Heart Association , Arritmias Cardíacas/diagnóstico , Arritmias Cardíacas/cirurgia , Educação Profissionalizante/normas , Técnicas Eletrofisiológicas Cardíacas/tendências , Humanos , Competência Profissional/normas , Ensino/normas , Estados UnidosAssuntos
American Heart Association , Cardiologia/normas , Competência Clínica/normas , Diagnóstico por Imagem/normas , Teste de Esforço/normas , Medicina Interna/normas , Garantia da Qualidade dos Cuidados de Saúde , Cardiologia/educação , Cardiologia/métodos , Criança , Ecocardiografia/normas , Humanos , Medicina Interna/educação , Medicina Interna/métodos , Pediatria/educação , Pediatria/métodos , Pediatria/normas , Angiografia Cintilográfica/normas , Estados UnidosRESUMO
In a study of the technique employed by the Canadian Red Cross Blood Transfusion Service in Montreal, the authors found that the packed red blood cells from 10 healthy donors had a mean hematocrit of 83 +/- 1.45 with a 24-hour red cell survival after three weeks' storage of 79.4 +/- 2%. The technique used a centrifugal force of 6975 G, the practical maximum of present-day equipment. In addition to finding excellent survival of packed cells subjected to extreme plasma deprivation and extreme forces of centrifugation they also report excellent survival of stored, highly concentrated red cells infused under pressure.
Assuntos
Preservação de Sangue , Envelhecimento Eritrocítico , Hematócrito , Centrifugação , Humanos , Masculino , Pressão , ReticulócitosRESUMO
Two brothers 62 and 70 years old, without evidence of vitamin B12 lack, excreted 12 to 115 mg of methylmalonic acid daily (normal, less than 9 mg per day). Neither had anemia or hepatic dysfunction, and serum vitamin B12 concentrations ranged from 369 to 800 pg per milliliter. The propositus, the younger brother, continued to excrete excessive methylmalonate, 103 to 115 mg per day, after 2000 mug of parenterally administered vitamin B12 at the fifth and 11th months of study. Leukocyte activities of the cobalamin-linked enzyme methylmalonyl coenzyme A mutase were respectively reduced in the propositus and his brother, to 0.04 and 0.11 nmoles of 3-(14)-C Ls methylmalonyl coenzyme A metabolized per hour per milligram of leukocyte protein (normal, 0.286 +/- 0.079 [S.D.]). These activities were not enhanced by 2 mug of 5'-deoxyadenosylcobalamin added to the assays. A heritable benign form of adult methylmalonic aciduria rather than vitamin B12 lack best explains these findings.