Solubility of alkali metal halides in the ionic liquid [C4C1im][OTf].

The solubilities of the metal halides LiF, LiCl, LiBr, LiI, NaF, NaCl, NaBr, NaI, KF, KCl, KBr, KI, RbCl, CsCl, CsI, were measured at temperatures ranging from 298.15 to 378.15 K in the ionic liquid 1-butyl-3-methylimidazolium trifluoromethanesulfonate ([C4C1im][OTf]). Li(+), Na(+) and K(+) salts with anions matching the ionic liquid have also been investigated to determine how well these cations dissolve in [C4C1im][OTf]. This study compares the influence of metal cation and halide anion on the solubility of salts within this ionic liquid. The highest solubility found was for iodide salts, and the lowest solubility for the three fluoride salts. There is no outstanding difference in the solubility of salts with matching anions in comparison to halide salts. The experimental data were correlated employing several phase equilibria models, including ideal mixtures, van't Hoff, the λh (Buchowski) equation, the modified Apelblat equation, and the non-random two-liquid model (NRTL). It was found that the van't Hoff model gave the best correlation results. On the basis of the experimental data the thermodynamic dissolution parameters (ΔH, ΔS, and ΔG) were determined for the studied systems together with computed gas phase metathesis parameters. Dissolution depends on the energy difference between enthalpies of fusion and dissolution of the solute salt. This demonstrates that overcoming the lattice energy of the solid matrix is the key to the solubility of inorganic salts in ionic liquids.

[Can complaints to the Veterinary Disciplinary Board be prevented?]. / Zijn klachten bij het Veterinair Tuchtcollege te voorkomen?

Over the past few years the general public's perception of animals has changed in the Netherlands. Animals are increasingly thought of as 'noble animals" and not merely as beasts to serve humankind. This changed sentiment can best be exemplified by the fact that the Party for Animals won two seats in the recent parliamentary elections. To see whether this change is also mirrored in the development of Veterinary Disciplinary Law, the rulings of the Veterinary Disciplinary Board between 1992 and 2005 were retrieved and studied (first aim of the study). The Board, which is an independent court of justice, was set up in The Hague 1992 in accordance with the Veterinary Practice Act to improve the quality of veterinary practice. Any animal owner can submit a complaint about a veterinary practitioner, a veterinary nurse, an animal physiotherapist, or a lay obstetrician. A second aim of the study was to investigate why owners submit complaints, because these procedures are time-consuming and unpleasant for both parties. If the underlying causes of complaints can be identified, it may be possible to reduce the number of complaints. In total, 1023 rulings passed by the Veterinary Disciplinary Board between October 1992 and December 2005 were evaluated, using a standardized questionnaire. The results showed that in this period the rulings did not reflect the increased public interest in the position of animals: the case load did not change (on average 78 cases/year; varying between 58-103 cases/year), the proportion of complaints that were upheld did not change, and more severe penalties were not imposed. However; findings revealed that the underlying cause of the complaint was often (partly) 'emotional'. Different standards and values, treatment that does not meet the owner's expectations, a lack of empathy on the part of the veterinary practitioner, and communication problems all played an important role. Insight into these underlying problems may reduce the number of the complaints submitted to the Veterinary Disciplinary Board.

Compatibility of cyclopoid copepods with mosquito insecticides.

Larvivorous copepods (Macrocyclops, Mesocyclops and Acanthocyclops) were tested for their sensitivities to commonly used mosquito larvicides and adulticides. The cyclopoids were not harmed by Bacillus thuringiensis (H-14) (B.t.i.) or larviciding oil. Control of mosquito larvae in field trials was accelerated by applying B.t.i. at the same time cyclopoids were introduced to a breeding site. Among adulticides tested, the cyclopoids were least sensitive to permethrin. Field trials demonstrated that permethrin does not harm cyclopoids when applied at label specifications.

Strategies for the emergency control of arboviral epidemics in New Orleans.

A study was initiated to evaluate the effectiveness of aerial ULV spraying for the control of Aedes aegypti and Culex quinquefasciatus as an emergency antiepidemic measure against dengue fever and St. Louis encephalitis, respectively. Malathion was aerially applied at 219 ml/ha over 344 ha area of the Ninth Ward in New Orleans. Laboratory susceptibility tests and field-cage exposures indicated that the target populations were susceptible to malathion and that acceptable coverage of the study area occurred. Two consecutive aerial applications decreased the relative abundance and ovipositional activity of adult mosquitoes. However, suppression was transient and, in the event of an epidemic, multiple treatments may be required to decrease vector abundance below the threshold levels required for the spread of virus to the human populations.

DNA amplification of HIV genome in hemophiliacs and in newborns from seropositive mothers.

We evaluated the validity of DNA enzymatic amplification (PCR) in a population at risk for HIV-1 infection, consisting of hemophiliacs and children born to seropositive mothers. All but one of the seropositive hemophiliacs and controls were found positive with the three sets of primers. All the seronegative patients and controls were found negative in PCR. No correlation with the anti-nef serology was found, one seropositive being anti-nef negative and three seronegative anti-nef positive. The results obtained with PCR are in good agreement with classical serology, and this would suggest that the possible period of latency may not be as long as suspected. No seroconversion has been described in hemophiliacs since solvent-detergent inactivated blood products have been in use, and seronegative hemophiliacs no longer constitute a population at risk. Studies on seronegative sexual partners of seropositive patients would be of great interest. For newborns from seropositive mothers, PCR is the only possible technique in early age before seronegativation of the healthy children. Further studies will be required to determine the fiability and sensitivity of the test.