Detalhe da pesquisa
1.
Inflammatory Caspases: Toward a Unified Model for Caspase Activation by Inflammasomes.
Annu Rev Immunol
; 40: 249-269, 2022 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35080918
2.
Fluorochrome-labeled inhibitors of caspase-1 require membrane permeabilization to efficiently access caspase-1 in macrophages.
Eur J Immunol
; 54(5): e2350515, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38361219
3.
Extracorporeal Membrane Oxygenation-Dependent Fulminant Melioidosis From Caspase 4 Mutation Reversed by Interferon Gamma Therapy.
Clin Infect Dis
; 78(1): 94-97, 2024 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37647624
4.
Great balls of fire: activation and signalling of inflammatory caspases.
Biochem Soc Trans
; 49(3): 1311-1324, 2021 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34060593
5.
6.
MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition.
Nat Chem Biol
; 15(6): 556-559, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31086327
7.
Variation in hemolysin A expression between uropathogenic Escherichia coli isolates determines NLRP3-dependent vs. -independent macrophage cell death and host colonization.
FASEB J
; 33(6): 7437-7450, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30869997
8.
Cutting Edge: Blockade of Inhibitor of Apoptosis Proteins Sensitizes Neutrophils to TNF- but Not Lipopolysaccharide-Mediated Cell Death and IL-1ß Secretion.
J Immunol
; 200(10): 3341-3346, 2018 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29661823
9.
NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-4 and caspase-5.
Eur J Immunol
; 45(10): 2918-26, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26173988
10.
Caspase-7 uses an exosite to promote poly(ADP ribose) polymerase 1 proteolysis.
Proc Natl Acad Sci U S A
; 109(15): 5669-74, 2012 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22451931
11.
Inflammasomes in epithelial innate immunity: front line warriors.
FEBS Lett
; 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38485451
12.
NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasome.
Sci Signal
; 17(820): eabg8145, 2024 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38261657
13.
Caspase-4 dimerisation and D289 auto-processing elicit an interleukin-1ß-converting enzyme.
Life Sci Alliance
; 6(10)2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37558421
14.
Measuring Non-canonical Inflammasome Activation in Neutrophils.
Methods Mol Biol
; 2459: 29-37, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35212951
15.
Gasdermin D Cleavage Assay Following Inflammasome Activation.
Methods Mol Biol
; 2459: 39-49, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35212952
16.
Mathematical modelling of activation-induced heterogeneity in TNF, IL6, NOS2, and IL1ß expression reveals cell state transitions underpinning macrophage responses to LPS.
Wellcome Open Res
; 7: 29, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36072059
17.
Activation of the Non-canonical Inflammasome in Mouse and Human Cells.
Methods Mol Biol
; 2459: 51-63, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35212953
18.
Caspase-1 cleaves Bid to release mitochondrial SMAC and drive secondary necrosis in the absence of GSDMD.
Life Sci Alliance
; 3(6)2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32345661
19.
Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteria.
Nat Commun
; 11(1): 3276, 2020 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32581219
20.
Isolation of Neutrophil Nuclei for Use in NETosis Assays.
Bio Protoc
; 9(17): e3357, 2019 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33654856