Detalhe da pesquisa
1.
The role of lysosomal phospholipase A2 in the catabolism of bis(monoacylglycerol)phosphate and association with phospholipidosis.
J Lipid Res
; : 100574, 2024 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38857781
2.
Protein Arginine Methyltransferase 5 (PRMT5) Mutations in Cancer Cells.
Int J Mol Sci
; 24(7)2023 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37047013
3.
A New Paroxetine-Based GRK2 Inhibitor Reduces Internalization of the µ-Opioid Receptor.
Mol Pharmacol
; 97(6): 392-401, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32234810
4.
Identifying Cancer-Relevant Mutations in the DLC START Domain Using Evolutionary and Structure-Function Analyses.
Int J Mol Sci
; 21(21)2020 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-33142932
5.
Structural Basis of Lysosomal Phospholipase A2 Inhibition by Zn2.
Biochemistry
; 58(13): 1709-1717, 2019 04 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30830753
6.
The Quinazolinone Allosteric Inhibitor of PBP 2a Synergizes with Piperacillin and Tazobactam against Methicillin-Resistant Staphylococcus aureus.
Antimicrob Agents Chemother
; 63(5)2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30858202
7.
Determinants of pH profile and acyl chain selectivity in lysosomal phospholipase A2.
J Lipid Res
; 59(7): 1205-1218, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29724779
8.
Utilizing a structure-based docking approach to develop potent G protein-coupled receptor kinase (GRK) 2 and 5 inhibitors.
Bioorg Med Chem Lett
; 28(9): 1507-1515, 2018 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29627263
9.
Structural Determinants Influencing the Potency and Selectivity of Indazole-Paroxetine Hybrid G Protein-Coupled Receptor Kinase 2 Inhibitors.
Mol Pharmacol
; 92(6): 707-717, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29070696
10.
Conformational Dynamics in Penicillin-Binding Protein 2a of Methicillin-Resistant Staphylococcus aureus, Allosteric Communication Network and Enablement of Catalysis.
J Am Chem Soc
; 139(5): 2102-2110, 2017 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28099001
11.
Synergistic, collaterally sensitive ß-lactam combinations suppress resistance in MRSA.
Nat Chem Biol
; 11(11): 855-61, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26368589
12.
Discovery of antibiotic (E)-3-(3-carboxyphenyl)-2-(4-cyanostyryl)quinazolin-4(3H)-one.
J Am Chem Soc
; 137(5): 1738-41, 2015 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25629446
13.
In silico analysis of several frequent SLX4 mutations appearing in human cancers.
MicroPubl Biol
; 20242024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38828439
14.
Detection of driver mutations and genomic signatures in endometrial cancers using artificial intelligence algorithms.
PLoS One
; 19(2): e0299114, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38408048
15.
F-box DNA Helicase 1 (FBH1) Contributes to the Destabilization of DNA Damage Repair Machinery in Human Cancers.
Cancers (Basel)
; 15(18)2023 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37760409
16.
KAT5 histone acetyltransferase mutations in cancer cells.
MicroPubl Biol
; 20222022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36530474
17.
In silico analysis of a SLC6A4 G100V mutation in lung cancers.
MicroPubl Biol
; 20222022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36247322
18.
Pan-cancer analysis of co-occurring mutations in RAD52 and the BRCA1-BRCA2-PALB2 axis in human cancers.
PLoS One
; 17(9): e0273736, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36107942
19.
Exploration of mild copper-mediated coupling of organotrifluoroborates in the synthesis of thiirane-based inhibitors of matrix metalloproteinases.
Bioorg Med Chem Lett
; 21(9): 2675-8, 2011 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21256011
20.
A Genome-Wide Profiling of Glioma Patients with an IDH1 Mutation Using the Catalogue of Somatic Mutations in Cancer Database.
Cancers (Basel)
; 13(17)2021 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34503108