Distributed Ledger Technology for eHealth Identity Privacy: State of The Art and Future Perspective.

Electronic healthcare (eHealth) identity management (IdM) is a pivotal feature in the eHealth system. Distributed ledger technology (DLT) is an emerging technology that can achieve agreements of transactional data states in a decentralized way. Building identity management systems using Blockchain can enable patients to fully control their own identity and provide increased confidence in data immutability and availability. This paper presents the state of the art of decentralized identity management using Blockchain and highlights the possible opportunities for adopting the decentralized identity management approaches for future health identity systems. First, we summarize eHealth identity management scenarios. Furthermore, we investigate the existing decentralized identity management solutions and present decentralized identity models. In addition, we discuss the current decentralized identity projects and identify new challenges based on the existing solutions and the limitations when applying it to healthcare as a particular use case.

IoT-CCAC: a blockchain-based consortium capability access control approach for IoT.

Access control is a critical aspect for improving the privacy and security of IoT systems. A consortium is a public or private association or a group of two or more institutes, businesses, and companies that collaborate to achieve common goals or form a resource pool to enable the sharing economy aspect. However, most access control methods are based on centralized solutions, which may lead to problems like data leakage and single-point failure. Blockchain technology has its intrinsic feature of distribution, which can be used to tackle the centralized problem of traditional access control schemes. Nevertheless, blockchain itself comes with certain limitations like the lack of scalability and poor performance. To bridge the gap of these problems, here we present a decentralized capability-based access control architecture designed for IoT consortium networks named IoT-CCAC. A blockchain-based database is utilized in our solution for better performance since it exhibits favorable features of both blockchain and conventional databases. The performance of IoT-CCAC is evaluated to demonstrate the superiority of our proposed architecture. IoT-CCAC is a secure, salable, effective solution that meets the enterprise and business's needs and adaptable for different IoT interoperability scenarios.

Oral ingestion of lactic-acid bacteria by rats increases lymphocyte proliferation and interferon-gamma production.

The effect of feeding lactic-acid bacteria on indices of functions of lymphocytes obtained from Peyer's patches, peripheral blood and spleen from inbred Wistar-Furth rats were studied. Rats were fed on purified diets supplemented with 350 g milk or yoghurt/kg diet for 4 weeks. At the end of the feeding period, immune cells from the three sites were isolated and proliferation, interferon-gamma production and lymphocyte subset composition were studied. Rats consuming yoghurt had a greater in vitro proliferative response to yoghurt bacteria in the three lymphoid compartments, a greater interferon-gamma production in response to bacteria and concanavalin A in Peyer's patches and spleen, and a greater number of Peyer's patches B lymphocytes than milk-fed rats. Macrophage and T lymphocyte proportions and lymphocyte subset composition in the three sites were unaffected by yoghurt. These results indicate that feeding live bacteria contained in yoghurt may interact with the intestinal immune system, and influence the systemic immune system.