Detalhe da pesquisa
1.
Meropenem-ANT3310, a unique ß-lactam-ß-lactamase inhibitor combination with expanded antibacterial spectrum against Gram-negative pathogens including carbapenem-resistant Acinetobacter baumannii.
Antimicrob Agents Chemother
; 68(3): e0112023, 2024 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38289044
2.
Pharmacodynamics of the Novel Metallo-ß-Lactamase Inhibitor ANT2681 in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing Enterobacteriaceae.
Antimicrob Agents Chemother
; 64(11)2020 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32778549
3.
Higher levels of Pseudomonas aeruginosa LasB elastase expression are associated with early-stage infection in cystic fibrosis patients.
Sci Rep
; 13(1): 14208, 2023 08 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37648735
4.
Discovery of ANT3310, a Novel Broad-Spectrum Serine ß-Lactamase Inhibitor of the Diazabicyclooctane Class, Which Strongly Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacterales and Acinetobacter baumannii.
J Med Chem
; 63(24): 15802-15820, 2020 12 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33306385
5.
ANT2681: SAR Studies Leading to the Identification of a Metallo-ß-lactamase Inhibitor with Potential for Clinical Use in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing Enterobacteriaceae.
ACS Infect Dis
; 6(9): 2419-2430, 2020 09 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32786279
6.
SAR Studies Leading to the Identification of a Novel Series of Metallo-ß-lactamase Inhibitors for the Treatment of Carbapenem-Resistant Enterobacteriaceae Infections That Display Efficacy in an Animal Infection Model.
ACS Infect Dis
; 5(1): 131-140, 2019 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30427656